Prevalence and significance ofCYP2C19*2andCYP2C19*17alleles in a New Zealand acute coronary syndrome population

Interplay between Genetic and Clinical Variables Affecting Platelet Reactivity and Cardiac Adverse Events in Patients Undergoing Percutaneous Coronary Intervention

(2014) Jolanta M. Siller-Matula et al.   PLoS One

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update

(2013) S A Scott et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Personalized antiplatelet therapy according to CYP2C19 genotype after percutaneous coronary intervention: A randomized control trial

(2013) Xiang Xie et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Platelet reactivity in the early and late phases of acute coronary syndromes according to cytochrome P450 2C19 phenotypes

(2013) Zenko Nagashima et al.   Journal of Cardiology

Consensus and Update on the Definition of On-Treatment Platelet Reactivity to Adenosine Diphosphate Associated With Ischemia and Bleeding

(2013) Udaya S. Tantry et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Third Universal Definition of Myocardial Infarction

(2012) Kristian Thygesen et al.   CIRCULATION

Pharmacodynamic Effect of Switching Therapy in Patients With High On-Treatment Platelet Reactivity and Genotype Variation With High Clopidogrel Dose Versus Prasugrel

(2012) Gennaro Sardella et al.   Circulation-Cardiovascular Interventions

Suboptimal response to clopidogrel and the effect of prasugrel in acute coronary syndromes

(2012) L.R. Johnston et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

CYP2C19*2 and *17 Alleles Have a Significant Impact on Platelet Response and Bleeding Risk in Patients Treated With Prasugrel After Acute Coronary Syndrome

(2012) Thomas Cuisset et al.   JACC-Cardiovascular Interventions

Ticagrelor Versus Prasugrel in Acute Coronary Syndrome Patients With High On-Clopidogrel Platelet Reactivity Following Percutaneous Coronary Intervention

(2012) Dimitrios Alexopoulos et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Randomized Trial of Prasugrel Versus Clopidogrel in Patients With High Platelet Reactivity on Clopidogrel After Elective Percutaneous Coronary Intervention With Implantation of Drug-Eluting Stents

(2012) Dietmar Trenk et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Bedside Monitoring to Adjust Antiplatelet Therapy for Coronary Stenting

(2012) Jean-Philippe Collet et al.   NEW ENGLAND JOURNAL OF MEDICINE

The influence of CYP2C19*2 and *17 on on-treatment platelet reactivity and bleeding events in patients undergoing elective coronary stenting

(2012) Ankie M. Harmsze et al.   Pharmacogenetics and Genomics

Methodological considerations for the assessment of ADP induced platelet aggregation using the Multiplate® analyser

(2012) Lisa R. Johnston et al.   PLATELETS

CYP2C19 and ABCB1gene polymorphisms are differently distributed according to ethnicity in the Brazilian general population

(2011) Paulo CJL Santos et al.   BMC Medical Genetics

Effect of CYP2C19*2 and *3 Loss-of-Function Alleles on Platelet Reactivity and Adverse Clinical Events in East Asian Acute Myocardial Infarction Survivors Treated With Clopidogrel and Aspirin

(2011) Young-Hoon Jeong et al.   Circulation-Cardiovascular Interventions

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450-2C19 (CYP2C19) Genotype and Clopidogrel Therapy

(2011) S A Scott et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Variability in on-treatment platelet reactivity explained by CYP2C19*2 genotype is modest in clopidogrel pretreated patients undergoing coronary stenting

(2011) H. J. Bouman et al.   HEART

Standard- vs High-Dose Clopidogrel Based on Platelet Function Testing After Percutaneous Coronary Intervention

(2011) Matthew J. Price   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

High-resolution melting curve analysis to establish CYP2C19∗2 single nucleotide polymorphism: Comparison with hydrolysis SNP analysis

(2011) Manna Temesvári et al.   MOLECULAR AND CELLULAR PROBES

Diabetes and the platelet: Toward new therapeutic paradigms for diabetic atherothrombosis

(2010) Olivier Morel et al.   ATHEROSCLEROSIS

Cytochrome 2C19*17 Allelic Variant, Platelet Aggregation, Bleeding Events, and Stent Thrombosis in Clopidogrel-Treated Patients With Coronary Stent Placement

(2010) Dirk Sibbing et al.   CIRCULATION

Impact of P2Y12 Inhibition by Clopidogrel on Cardiovascular Mortality in Unselected Patients Treated by Percutaneous Coronary Angioplasty

(2010) Soraya El Ghannudi et al.   JACC-Cardiovascular Interventions

Reduced-Function CYP2C19 Genotype and Risk of Adverse Clinical Outcomes Among Patients Treated With Clopidogrel Predominantly for PCI

(2010) Jessica L. Mega et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON–TIMI 38 trial: a pharmacogenetic analysis

(2010) Jessica L Mega et al.   LANCET

Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial

(2010) Lars Wallentin et al.   LANCET

Frequency of CYP3A4, CYP3A5, CYP2C9, and CYP2C19 variant alleles in patients receiving clopidogrel that experience repeat acute coronary syndrome

(2009) Marcia L. Brackbill et al.   HEART AND VESSELS

Platelet Reactivity After Clopidogrel Treatment Assessed With Point-of-Care Analysis and Early Drug-Eluting Stent Thrombosis

(2009) Dirk Sibbing et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes

(2009) Lars Wallentin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation

(2008) Matthew J. Price et al.   EUROPEAN HEART JOURNAL

Genetic Determinants of Response to Clopidogrel and Cardiovascular Events

(2008) Tabassome Simon et al.   NEW ENGLAND JOURNAL OF MEDICINE

CYP2C19 and nongenetic factors predict poor responsiveness to clopidogrel loading dose after coronary stent implantation

(2008) Tobias Geisler et al.   PHARMACOGENOMICS