Article
Engineering, Chemical
Clara Hartmanshenn, Madeline Halota, Prin Chaksmithanont, Carlin Leung, Johannes G. Khinast, Charles D. Papageorgiou, Christopher Mitchell, Justin L. Quon, Benjamin J. Glasser
Summary: The study found that the heating time of particle beds in heated bladed mixers depends on the relationship between the fill level, mixer diameter, and the heating area relative to material amount, as well as bed compression and mixing rate.
Article
Engineering, Chemical
Veerakiet Boonkanokwong, Johannes G. Khinast, Benjamin J. Glasser
Summary: The study found that when the mixer diameter to particle diameter ratio was larger than a certain critical size, granular flow behaviors and mixing kinetics followed simple scaling relations and were independent of system size. By keeping the Bond number constant, the flow behavior and mixing patterns remained unchanged, showing that larger particles can simulate the flow of smaller cohesive particles in a bladed mixer by matching the Bond numbers.
ADVANCED POWDER TECHNOLOGY
(2021)
Article
Engineering, Chemical
Jieqing Gan, Zongyan Zhou, Aibing Yu
Summary: This paper presents a numerical study of the mixing of ellipsoidal particles in a bladed mixer using the discrete element method. The results show that oblate ellipsoids have poorer mixing quality and lower mixing rates compared to spheres and prolate ellipsoids. Spheres generally mix faster than ellipsoids, and ellipsoids demonstrate higher average velocity and friction forces than spheres. The study also investigates the effect of sliding friction on mixing rate, particle velocities, and blade torque, indicating a significant relationship between particle shape, sliding friction, and energy consumption.
Article
Engineering, Chemical
Marv J. Khala, Colin Hare, Chuan-Yu Wu, Navin Venugopal, Martin J. Murtagh, Tim Freeman
Summary: The rheological behavior of a dense granular bed under dynamic conditions is investigated using the Discrete Element Method. The distribution of stresses and strain rates in the bed, as well as their dependence on material properties and blade operational conditions, are analyzed. The study proposes a predictive model for computing the average shear stress in the granular bed based on blade torque, considering the effects of blade tip speed, particle aspect ratio, and interfacial energy.
Article
Engineering, Chemical
Angga Pratama Herman, Jieqing Gan, Aibing Yu
Summary: This study utilizes GPU-based DEM to investigate particle mixing in bladed mixers at different scales. Results indicate that maintaining geometric similarity while scaling up mixers results in similar mixing quality at the same Froude number, although larger mixers require longer mixing times. Correlations are proposed to predict various parameters as functions of scale-up ratio and Froude number, and a similarity study suggests that maintaining mixing rate produces consistent mixing performance across all mixer sizes.
Article
Engineering, Geological
Bruna de Carvalho Faria Lima Lopes, Alessandro Tarantino
Summary: This paper presents an analysis of the long-term stability of a large unsupported cave excavated in granular cohesionless material in Ficulle, Italy. It investigates the role of suction in enhancing shear strength and contributing to the long-term stability of geo-structures. The study demonstrates the potential long-lasting effects of suction on the stability of geological structures.
Article
Engineering, Chemical
Evgeny Rabinovich, Haim Kalman, Per F. Peterson
Summary: This study presents a new theoretical model for granular materials flow regimes during discharge from wedgeshape silos, which has been validated by comparing with experimental results. The proposed generalized flow regime map should help designers to increase accuracy and flexibility in the granules flow regime assessment.
Article
Engineering, Chemical
Prin Chaksmithanont, Felix Milman, Carlin Leung, Johannes G. Khinast, Charles D. Papageorgiou, Christopher Mitchell, Justin L. Quon, Benjamin J. Glasser
Summary: This study focuses on scaling up the granular flow in an agitated dryer by measuring the impeller torque. The torque was found to increase linearly with material bed height and was affected by the particle size. The bulk friction coefficient and material cohesiveness were determined based on the correlation between normal stresses and shear stresses. Torque predictions from the bulk friction coefficients showed good agreement with measurements.
Article
Engineering, Chemical
Gul Niamat Shah, Muhammad Shafiq Siraj
Summary: This study investigated the mixing characteristics of dry and wet granular flows inside a vertical cylindrical mixer using numerical simulations. The effects of blade rake angle and moisture content on mixing efficiency were analyzed, revealing that a two-bladed mixer is more suitable for mixing at certain moisture contents compared to a four-bladed mixer.Various factors such as blade design and moisture content need to be carefully considered for specific applications.
PARTICULATE SCIENCE AND TECHNOLOGY
(2021)
Article
Engineering, Environmental
Yijun Song, Meiri Wang, Jing Li, Hongtao Cui, Hongjun Su, Yuanyuan Liu
Summary: This study successfully synthesized LiNi1/3Co1/3Mn1/3O2 material with superior performance using a high shear mixer-assisted coprecipitation method, offering high discharge capacity and excellent cycling stability, with potential for application in large-scale production.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Engineering, Multidisciplinary
Meng Jiang, Cailing Liu, Xin Du, Rongbiao Huang, Lei Dai, Hao Yuan
Summary: The study introduced a flow rate measuring method based on the correlation between sensor voltage and particles flow rate, and designed experiments to demonstrate its feasibility and accuracy. The results showed a strong correlation between voltage and flow rate, with the measurement accuracy of the accumulation method (AM) higher than the sorting method (SM).
Article
Computer Science, Interdisciplinary Applications
Qing Chen, Yan Gao, Quan Yuan, Yu-Hsing Wang
Summary: The study reveals that during shearing, particle nonaffine displacement and rotation are closely related to the development of shear bands, and different types of contact motions have varying impacts on sample deformation.
COMPUTERS AND GEOTECHNICS
(2022)
Article
Engineering, Geological
Wei Hu, Yangshuai Zheng, Mauri Mcsaveney, Qiang Xu, Runqiu Huang, Li Zhou
Summary: Shear zone is widely observed in natural faults, landslides, and laboratory experiments. Understanding the evolution of shear zones in granular materials is crucial in studying the dynamics of landslides and faults. In this study, ring-shear experiments and high-resolution X-ray CT were used to investigate the evolution of strain localization and shear-zone internal structure in cohesive and non-cohesive granular materials. The results revealed that shear displacement led to rounding of large particles inside the shear zone and the formation of fine-particle layers on either side of the shear zone during shear localization.
ENGINEERING GEOLOGY
(2023)
Article
Engineering, Chemical
J. Krzyzanowski, J. Tejchman, W. Solowski, M. Wojcik
Summary: This paper focuses on the confined flow of cohesionless sand in a silo using the material point method (MPM). Different initial void ratios and wall roughness were considered in the simulations, with emphasis on the evolution of shear zones and their impact on wall stresses during flow. The numerical findings enhance the understanding of shear localization in granular materials and its effects on wall pressures in confined silo flow.
Article
Computer Science, Interdisciplinary Applications
Lihong Tong, Li Fu, Changjie Xu, Haibin Ding, Min Xiao
Summary: In this study, the effect of loading rate on the strength of granular material systems was investigated. A general frictional coefficient for the 2D granular material system was obtained based on the rate-state shear strength theory by considering loading rate and particle rotation. A 2D discrete element simulation experiment was conducted using spherical glass beads system with different combinations of confining pressures and loading rates. The results show that high loading rates significantly affect the mechanical behavior of the granular material system and a critical loading rate was identified. The proposed theoretical model provides a helpful approach for studying the strength of granular materials and determining their strength for practical engineering projects.
COMPUTERS AND GEOTECHNICS
(2023)
Article
Engineering, Chemical
Clara Hartmanshenn, Johannes G. Khinast, Charles D. Papageorgiou, Chris Mitchell, Justin Quon, Benjamin J. Glasser
Article
Engineering, Chemical
Luca Orefice, Johannes G. Khinast
Article
Engineering, Chemical
T. Forgber, P. Toson, S. Madlmeir, H. Kureck, Johannes G. Khinast, Dalibor Jajcevic
Article
Pharmacology & Pharmacy
Jakob Rehrl, Martin Kirchengast, Selma Celikovic, Stephan Sacher, Julia Kruisz, Johannes Khinast, Martin Horn
JOURNAL OF PHARMACEUTICAL INNOVATION
(2020)
Article
Chemistry, Medicinal
Eva Faulhammer, Julia Kruisz, Otto Scheibelhofer, Jakob Rehrl, Andreas Witschnigg, Johannes G. Khinast
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
(2020)
Article
Chemistry, Applied
Manuel Zettl, Manuel Kreimer, Isabella Aigner, Thomas Mannschott, Peter van der Wel, Johannes Khinast, Markus Krumme
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2020)
Article
Engineering, Chemical
Luca Orefice, Johannes G. Khinast
Article
Engineering, Chemical
Otto Scheibelhofer, Julia Kruisz, Jakob Rehrl, Eva Faulhammer, Andreas Witschnigg, Johannes G. Khinast
Article
Pharmacology & Pharmacy
Jakob Rehrl, Stephan Sacher, Martin Horn, Johannes Khinast
Article
Engineering, Chemical
Sara Fathollahi, Eva Faulhammer, Benjamin J. Glasser, Johannes G. Khinast
ADVANCED POWDER TECHNOLOGY
(2020)
Article
Engineering, Chemical
Veerakiet Boonkanokwong, Johannes G. Khinast, Benjamin J. Glasser
Summary: The study found that when the mixer diameter to particle diameter ratio was larger than a certain critical size, granular flow behaviors and mixing kinetics followed simple scaling relations and were independent of system size. By keeping the Bond number constant, the flow behavior and mixing patterns remained unchanged, showing that larger particles can simulate the flow of smaller cohesive particles in a bladed mixer by matching the Bond numbers.
ADVANCED POWDER TECHNOLOGY
(2021)
Article
Chemistry, Physical
Wai Thet Aung, Veerakiet Boonkanokwong
Summary: This research aimed to develop a self-microemulsifying delivery system (SMEDS) to increase the dissolution rate of astaxanthin (AST). The optimized AST SMEDS composed of 33.67% rice bran oil, 34.70% Kolliphor(R) RH40, and 31.63% Span(R) 20, and showed enhanced dissolution compared to raw AST powder. The study also showed that surfactant and cosurfactant inversely affected droplet size changes.
JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Wai Thet Aung, Hnin Ei Ei Khine, Chatchai Chaotham, Veerakiet Boonkanokwong
Summary: The study aimed to develop AST-loaded SMEDDS tablets and evaluate their properties. By adding hydrophilic polymers, supersaturation and dissolution of AST were achieved. The optimized tablets showed good performance and significantly improved dissolution and stability of the drug. Cellular uptake and antioxidant effects demonstrated enhanced drug permeation and bioavailability.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Pharmacology & Pharmacy
Wai Thet Aung, Peerawas Kopongpanich, Veerakiet Boonkanokwong
Summary: This study developed solid astaxanthin-encapsulated self-microemulsifying delivery system (S-AST SMEDS) spray-dried particles and investigated the effect of materials on product characteristics. The spray-dried powders showed improved AST dissolution rate.
Review
Biophysics
Maxius Gunawan, Veerakiet Boonkanokwong
Summary: Lipid nanoparticles have been used to enhance the delivery of antioxidants in the gastrointestinal tract, overcoming challenges such as low solubility and stability. These nanoparticles can improve the bioavailability and effectiveness of antioxidant compounds, making them valuable in nutraceutical formulations.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Engineering, Chemical
Yongxiang Wu, Nguyen Thi Hong Nhung, Deqian Zeng, Nengneng Luo, Akira Otsuki, Gjergj Dodbiba, Toyohisa Fujita
Summary: This study proposed a novel method for synthesizing flower-like vaterite calcium carbonate using nanobubble-containing ethanol and water mixed solution as the solvent and discussed the formation mechanism of vaterite with different shapes. The synthesized vaterite has significant practical interest in the integrated treatment of wastewater contaminated by heavy metals with effective Cd(II) removal, providing a promising field for studying heavy metal and pollutant adsorption in the liquid phase.
ADVANCED POWDER TECHNOLOGY
(2024)
Article
Engineering, Chemical
Jian Gong, Lipo Cheng, Ming Liu, Jie Jiang, Xiaoduo Ou
Summary: This study investigates the effects of particle shape on the collapse of granular columns using the discrete element method. The results show that particle shape has a significant impact on deposition morphology, energy evolution, and mechanical coordination number. Sphericity and angularity are identified as the most important macroscale factors, while roughness has a weaker microscale influence.
ADVANCED POWDER TECHNOLOGY
(2024)