Article
Agriculture, Multidisciplinary
Santiago Lopez-Miranda, Daniel Berdejo, Elisa Pagan, Diego Garcia-Gonzalo, Rafael Pagan
Summary: The study demonstrated that HP-alpha- and HP-gamma-CD are suitable alternatives for encapsulating carvacrol and thymol to preserve their antimicrobial activities.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Pharmacology & Pharmacy
Jan Kozak, Claire Chretien, Yann Pellequer, Alf Lamprecht
Summary: The suitability of dimethyl sulfoxide in formulating spray-freeze-dried particles was evaluated. Spray-freeze-dried lyospheres (R) prepared from dimethyl sulfoxide solutions showed rapid dissolution and increased bioavailability, making it applicable for poorly water-soluble drugs/excipients.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Food Science & Technology
Preethi Jayaprakash, Claire Gaiani, Jean-Maxime Edorh, Frederic Borges, Elodie Beaupeux, Audrey Maudhuit, Stephane Desobry
Summary: This study investigates the benefits and drawbacks of electrostatic spray drying (ESD), a novel technique that uses electrostatic charge and lower temperatures to encapsulate lactic acid bacteria. The study compares the viability of Lacticaseibacillus rhamnosus GG (LGG) using different encapsulation agents and finds that ESD preserves more LGG cells during processing and provides better stability during storage compared to traditional spray drying (SD) and freeze drying (FD).
Review
Pharmacology & Pharmacy
Ji Young Yu, Piyanan Chuesiang, Gye Hwa Shin, Hyun Jin Park
Summary: Liposomes have potential as drug delivery systems, but issues such as self-aggregation, coalescence, flocculation, and precipitation may occur during formulation or storage. Post-processing techniques like freeze drying, spray drying, and spray freeze drying have been used to increase the stability of liposomes. The use of protective agents to overcome limitations of each process is also crucial.
Article
Chemistry, Applied
J. Alarcon-Moyano, D. Acuna, S. Matiacevich, L. Caballero, F. Melo, F. Quero, P. Diaz-Calderon
Summary: This study evaluated the physical-chemical properties and structure of cellulose nanocrystals (CNC) dried by two different methods: Spray-Drying (SD) or Freeze-Drying (FD). The results showed that the drying method influenced the size, aspect ratio, and sorption of CNC. However, it did not affect zeta potential, crystallinity, or degradation temperature. The study suggests that the drying method plays a role in modifying the physico-chemical properties of CNC.
FOOD HYDROCOLLOIDS
(2023)
Review
Food Science & Technology
Dian Shofinita, Dianika Lestari, Lienda Aliwarga, Giovanni Arneldi Sumampouw, Sekar Arum Ambarwati, Karen Christine Gunawan, Amarthya Benigna Achmadi
Summary: Drying is a crucial step in coffee production to prevent microbial growth and extend coffee's storage time. Mechanical drying methods have been developed, but they may alter the physicochemical properties and compounds in coffee. Thus, maintaining these factors is vital as they impact the stability, reconstitution, and aroma of coffee, ultimately determining its quality. This review focuses on the effects of spray-drying, freeze-drying, and spray-freeze-drying on coffee's physicochemical properties and discusses their impact on organoleptic properties. Possible advancements such as encapsulation, porous frozen samples, and total solid enhancement of raw materials are highlighted.
FOOD AND BIOPROCESS TECHNOLOGY
(2023)
Article
Food Science & Technology
Delal Meryem Yaman, Derya Kocak Yanik, Aysel Elik Demir, Hicran Uzun Karka, Gamze Guclu, Serkan Selli, Hasim Kelebek, Fahrettin Gogus
Summary: This study aimed to evaluate the effects of different ratios of gum arabic to maltodextrin and various encapsulation techniques on the properties of powdered substance and the retention of terebinth fruit oil aroma. The emulsion stability was highest at a gum arabic to maltodextrin ratio of 75:25, showing minimal creaming and even dispersion. Spray drying with an ultrasonic nozzle and a two-fluidized nozzle achieved the highest encapsulation efficiency (>90%), particularly for retaining volatiles.
Article
Engineering, Chemical
Preethi Jayaprakash, Claire Gaiani, Jean-Maxime Edorh, Elodie Beaupeux, Audrey Maudhuit, Stephane Desobry
Summary: In this study, electrostatic spray drying (ESD) was used for the first time to encapsulate beta-galactosidase (beta-gal) and compared with conventional spray drying (SD) and freeze drying (FD) techniques. The results showed that ESD at intermediate temperatures produced microparticles with better characteristics and similar residual enzyme activity to FD in maltodextrin, trehalose, and shellac matrices. Therefore, ESD can be considered as an alternative technique to FD that is efficient, time-saving, and cost-effective.
JOURNAL OF FOOD ENGINEERING
(2023)
Article
Engineering, Chemical
Daniel Tristan Osanloo, Jonas Fransson, Bjorn Bergenstahl, Anna Millqvist-Fureby
Summary: This study investigates the effects of different drying technologies on the structure and solid-state properties of protein formulations. The results show that mannitol partially dissolves in amorphous trehalose, reducing the glass transition temperature. A minimum of 50% mannitol is required to achieve a scaffolding effect. Poor structural stability is observed at 25% mannitol, regardless of the drying technology.
Article
Food Science & Technology
Nisha Chhabra, Mehak Arora, Diksha Garg, Mahesh Kumar Samota
Summary: Drying is a critical process for extending the shelf life of food products, and spray drying and freeze drying are commonly used methods. A novel technique called spray freeze drying combines the advantages of traditional freeze drying and spray drying. This article explores various spray freeze-drying methods, compares them based on factors such as chilling medium and atomization settings, and discusses their applications in preserving bioactive compounds in the food industry.
Review
Biochemistry & Molecular Biology
Ivana Buljeta, Anita Pichler, Josip Simunovic, Mirela Kopjar
Summary: Polyphenols are important phytochemicals beneficial for human health, but their utilization is limited by low stability. Encapsulation technologies like spray-drying and freeze-drying help overcome these limitations and create more efficient delivery systems.
Article
Pharmacology & Pharmacy
Jason C. K. Lo, Harry W. Pan, Jenny K. W. Lam
Summary: The study evaluated the conditions and formulation of inhalable dry powders containing biological medicines produced by spray-freeze-drying (SFD), with atomization gas flow rate identified as a significant factor influencing the powder formulations and protein aggregation. High atomization gas flow rate induced aggregation, highlighting the need for further optimization.
Review
Chemistry, Applied
Bertrand Muhoza, Huang Yuyang, Angelo Uriho, Jean Damascene Harindintwali, Qian Liu, Yang Li
Summary: The charge neutralization between oppositely charged polyelectrolytes can create complex coacervate, a rich colloidal poly-electrolyte phase. Complex coacervates have the ability to encapsulate bioactive ingredients. However, drying stresses can impact the stability and release properties of these encapsulates. This review evaluates the current research on spray-and freeze-dried microcapsules prepared by complex coacervation method, exploring the effects of crosslinkers and protectants on the dried coacervated microcapsules.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Multidisciplinary
Giulia Di Prima, Antonino Scurria, Giuseppe Angellotti, Elena Belfiore, Mario Pagliaro, Francesco Meneguzzo, Viviana De Caro, Rosaria Ciriminna
Summary: The comparison between grapefruit IntegroPectin powders isolated via spray drying and freeze drying provides relevant information regarding phenolic content, quantification of flavonoids, radical scavenging activity, total protein content, and pH of aqueous solutions. The two drying methods yield similar pectins, except for protein content and antioxidant power. Optimizing the spray drying parameters allows for a nearly quantitative yield, approaching that obtained via freeze drying (>95%).
SUSTAINABLE CHEMISTRY AND PHARMACY
(2022)
Article
Pharmacology & Pharmacy
Marija Banozic, Malgorzata Krzywonos, Krunoslav Aladic, Hanna Pinkowska, Igor Mucha, Adrianna Zlocinska, Stela Jokic
Summary: This study evaluated the encapsulation of hesperidin using freeze drying and spray drying techniques with maltodextrin and gum arabic. The results showed that these encapsulation techniques significantly improved the solubility and stability of hesperidin, while also enhancing its flow properties.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Behnaz Daneshmand, Homa Faghihi, Maryam Amini Pouya, Shabnam Aghababaie, Majid Darabi, Alireza Vatanara
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
(2019)
Article
Pharmacology & Pharmacy
Mahdieh Farhangi, Arash Mahboubi, Farzad Kobarfard, Alireza Vatanara, Seyed Alireza Mortazavi
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
(2019)
Review
Pharmacology & Pharmacy
Ali Ahmadi Tehrani, Mohammad Mahdi Omranpoor, Alireza Vatanara, Mohammad Seyedabadi, Vahid Ramezani
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
(2019)
Article
Pharmacology & Pharmacy
Yasaman Mirfakhraei, Homa Faghihi, Amir Hossein Mohammad Zade, Majid Darabi, Alireza Vatanara
Article
Pharmacology & Pharmacy
Homa Faghihi, Abdolhossein Rouholamini Najafabadi, Zahra Daman, Elham Ghasemian, Hamed Montazeri, Alireza Vatanara
Article
Medicine, Research & Experimental
Fakhrossadat Emami, Asmita Banstola, Alireza Vatanara, Sooyeon Lee, Jong Oh Kim, Jee-Heon Jeong, Simmyung Yook
MOLECULAR PHARMACEUTICS
(2019)
Article
Pharmacology & Pharmacy
Rayehe Teymouri Rad, Simin Dadashzadeh, Alireza Vatanara, Sonia Alavi, Elham Ghasemian, Seyed Alireza Mortazavi
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2019)
Article
Biophysics
Tahereh Dara, Alireza Vatanara, Mohsen Nabi Meybodi, Molood Alsadat Vakilinezhad, Soroor Sadegh Malvajerd, Faezeh Vakhshiteh, Azam Shamsian, Mohammad Sharifzadeh, Hooman Kaghazian, Mohammad Hossein Mosaddegh
COLLOIDS AND SURFACES B-BIOINTERFACES
(2019)
Article
Pharmacology & Pharmacy
Maedeh Shams Nouraei, Homa Faghihi, Abdolhossein Roulholamini Najafabadi, Amir Hossein Mohammad Zadeh, Majid Darabi, Alireza Vatanara
Article
Pharmacology & Pharmacy
Fakhrossadat Emami, Alireza Vatanara, Faezeh Vakhshiteh, Yejin Kim, Tae Wan Kim, Dong Hee Na
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2019)
Article
Pharmacology & Pharmacy
Mojgan Allahyari, Reyhaneh Mohabati, Alireza Vatanara, Majid Golkar
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2020)
Article
Behavioral Sciences
Tahereh Dara, Alireza Vatanara, Mohammad Sharifzadeh, Samira Khani, Molood Alsadat Vakilinezhad, Faezeh Vakhshiteh, Mohsen Nabi Meybodi, Soroor Sadegh Malvajerd, Shokoufeh Hassani, Mohammad Hossein Mosaddegh
NEUROBIOLOGY OF LEARNING AND MEMORY
(2019)
Article
Pharmacology & Pharmacy
Ahmadreza Barazesh, Kambiz Gilani, Mohammadreza Rouini, Mohammad Ali Barghi
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
(2020)
Article
Pharmacology & Pharmacy
Sara Bahrainian, Mohammadreza Rouini, Kambiz Gilani
Summary: This study aimed to achieve a dry powder formulation of vancomycin for inhalation by evaluating the effect of pH and excipient type and percentage used. The combination of two excipients, hydroxypropyl beta-cyclodextrin and trehalose, showed improved aerosolization performance. The optimized formulation containing 17.39% hydroxypropyl beta-cyclodextrin and 29.61% trehalose demonstrated good physical stability over 3 months of storage.
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
(2021)
Article
Pharmacology & Pharmacy
Seyyed Pouya Hadipour Moghaddam, Sajjad Farhat, Alireza Vatanara
ADVANCED PHARMACEUTICAL BULLETIN
(2018)
Article
Engineering, Chemical
Yongxiang Wu, Nguyen Thi Hong Nhung, Deqian Zeng, Nengneng Luo, Akira Otsuki, Gjergj Dodbiba, Toyohisa Fujita
Summary: This study proposed a novel method for synthesizing flower-like vaterite calcium carbonate using nanobubble-containing ethanol and water mixed solution as the solvent and discussed the formation mechanism of vaterite with different shapes. The synthesized vaterite has significant practical interest in the integrated treatment of wastewater contaminated by heavy metals with effective Cd(II) removal, providing a promising field for studying heavy metal and pollutant adsorption in the liquid phase.
ADVANCED POWDER TECHNOLOGY
(2024)
Article
Engineering, Chemical
Jian Gong, Lipo Cheng, Ming Liu, Jie Jiang, Xiaoduo Ou
Summary: This study investigates the effects of particle shape on the collapse of granular columns using the discrete element method. The results show that particle shape has a significant impact on deposition morphology, energy evolution, and mechanical coordination number. Sphericity and angularity are identified as the most important macroscale factors, while roughness has a weaker microscale influence.
ADVANCED POWDER TECHNOLOGY
(2024)