Enzyme Prodrug Therapy Engineered into Biomaterials

Biocatalytic polymer thin films: optimization of the multilayered architecture towards in situ synthesis of anti-proliferative drugs

(2014) Sidsel Ø. Andreasen et al.   Nanoscale

Narrow Therapeutic Window of Ribavirin as an Inhibitor of Nitric Oxide Synthesis is Broadened by Macromolecular Prodrugs

(2013) Benjamin M. Wohl et al.   BIOMACROMOLECULES

Macromolecular prodrugs of ribavirin combat side effects and toxicity with no loss of activity of the drug

(2013) Mille B. L. Kryger et al.   CHEMICAL COMMUNICATIONS

Bacterial-directed enzyme prodrug therapy

(2013) Panos Lehouritis et al.   JOURNAL OF CONTROLLED RELEASE

Lipogels: surface-adherent composite hydrogels assembled from poly(vinyl alcohol) and liposomes

(2013) Bettina E. B. Jensen et al.   Nanoscale

Maturing antibody–drug conjugate pipeline hits 30

(2013) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Biocatalytic Polymer Coatings: On-Demand Drug Synthesis and Localized Therapeutic Effect under Dynamic Cell Culture Conditions

(2013) Betina Fejerskov et al.   Small

Engineering Surface Adhered Poly(vinyl alcohol) Physical Hydrogels as Enzymatic Microreactors

(2012) Betina Fejerskov et al.   ACS Applied Materials & Interfaces

Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System

(2012) Andrea Mickova et al.   BIOMACROMOLECULES

A review of polyvinyl alcohol and its uses in cartilage and orthopedic applications

(2012) Maribel I. Baker et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Bioresorbable Surface-Adhered Enzymatic Microreactors Based on Physical Hydrogels of Poly(vinyl alcohol)

(2012) Betina Fejerskov et al.   LANGMUIR

Combinatorial drug therapy for cancer in the post-genomic era

(2012) Bissan Al-Lazikani et al.   NATURE BIOTECHNOLOGY

Substrate Mediated Enzyme Prodrug Therapy

(2012) Betina Fejerskov et al.   PLoS One

Prolonged nerve blockade delays the onset of neuropathic pain

(2012) S. A. Shankarappa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microstructured, Functional PVA Hydrogels through Bioconjugation with Oligopeptides under Physiological Conditions

(2012) Siow-Feng Chong et al.   Small

Surface-Adhered Composite Poly(Vinyl Alcohol) Physical Hydrogels: Polymersome-Aided Delivery of Therapeutic Small Molecules

(2012) Leticia Hosta-Rigau et al.   Advanced Healthcare Materials

Effects of Curcumin on Lung Histopathology and Fungal Burden in a Mouse Model of Chronic Asthma and Oropharyngeal Candidiasis

(2011) Meral Karaman et al.   ARCHIVES OF MEDICAL RESEARCH

Core cross-linked block ionomer micelles as pH-responsive carriers for cis-diamminedichloroplatinum(II)

(2011) Hardeep S. Oberoi et al.   JOURNAL OF CONTROLLED RELEASE

Poly(Vinyl Alcohol) Physical Hydrogels: New Vista on a Long Serving Biomaterial

(2011) Marie-Helene Alves et al.   MACROMOLECULAR BIOSCIENCE

Curcumin promotes degradation of inducible nitric oxide synthase and suppresses its enzyme activity in RAW 264.7 cells

(2010) Peiling Ben et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Targeted Enzyme Prodrug Therapies

(2010) N. Schellmann et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Large Area Protein Patterning Reveals Nanoscale Control of Focal Adhesion Development

(2010) Jenny Malmström et al.   NANO LETTERS

Controlling Cell Behavior Through the Design of Polymer Surfaces

(2010) Natália M. Alves et al.   Small

Polymers for Drug Delivery Systems

(2010) William B. Liechty et al.   Annual Review of Chemical and Biomolecular Engineering

Drug-eluting bead therapy in primary and metastatic disease of the liver

(2010) Stewart Carter et al.   HPB

Hydrogels in Regenerative Medicine

(2009) Brandon V. Slaughter et al.   ADVANCED MATERIALS

Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement

(2009) Jack Cuzick et al.   LANCET ONCOLOGY

Hydrogel nanoparticles in drug delivery

(2008) Mehrdad Hamidi et al.   ADVANCED DRUG DELIVERY REVIEWS

A Novel Cross-linked Poly(vinyl alcohol) (PVA) for Vascular Grafts

(2008) Marc Chaouat et al.   ADVANCED FUNCTIONAL MATERIALS

Gene Directed Enzyme Prodrug Therapy for Ovarian Cancer: Could GDEPT Become a Promising Treatment Against Ovarian Cancer?

(2008) Akihiro Nawa et al.   Anti-Cancer Agents in Medicinal Chemistry

Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

(2008) Ajaikumar B. Kunnumakkara et al.   CANCER LETTERS

Hydrogels in drug delivery: Progress and challenges

(2008) Todd R. Hoare et al.   POLYMER

Nanotechnology and Cancer

(2007) James R. Heath et al.   Annual Review of Medicine

Immobilization of lipase enzyme in polyvinyl alcohol (PVA) nanofibrous membranes

(2007) Y. Wang et al.   JOURNAL OF MEMBRANE SCIENCE