Cholestatic liver (dys)function during sepsis and other critical illnesses

Conjugated bilirubin triggers anemia by inducing erythrocyte death

(2014) Elisabeth Lang et al.   HEPATOLOGY

Pleiotropic Roles of Bile Acids in Metabolism

(2013) Thomas Q. de Aguiar Vallim et al.   Cell Metabolism

Nuclear Receptors as Drug Targets in Cholestatic Liver Diseases

(2013) Emina Halilbasic et al.   Clinics in Liver Disease

Hypoxic liver injury and cholestasis in critically ill patients

(2013) Thomas Horvatits et al.   Current Opinion in Critical Care

Withholding parenteral nutrition during critical illness increases plasma bilirubin but lowers the incidence of biliary sludge

(2013) Yoo-Mee Vanwijngaerden et al.   HEPATOLOGY

An updated review on drug-induced cholestasis: Mechanisms and investigation of physicochemical properties and pharmacokinetic parameters

(2013) Kyunghee Yang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Remifentanil protects liver against ischemia/reperfusion injury through activation of anti-apoptotic pathways

(2013) Ge Zhao et al.   JOURNAL OF SURGICAL RESEARCH

Bile acid receptors as targets for drug development

(2013) Frank G. Schaap et al.   Nature Reviews Gastroenterology & Hepatology

Reduced Cortisol Metabolism during Critical Illness

(2013) Eva Boonen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of Parenteral Nutrition Versus Fasting on Hepatic Bile Acid Production and Transport in a Rabbit Model of Prolonged Critical Illness

(2013) Yoo-Mee Vanwijngaerden et al.   SHOCK

Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial

(2013) Greet Hermans et al.   Lancet Respiratory Medicine

Hyperbilirubinemia, Augmentation of Endothelial Function, and Decrease in Oxidative Stress in Gilbert Syndrome

(2012) Tatsuya Maruhashi et al.   CIRCULATION

Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease

(2012) Geoffrey Porez et al.   JOURNAL OF LIPID RESEARCH

Heme Oxygenase-1 Protects Retinal Endothelial Cells against High Glucose- and Oxidative/Nitrosative Stress-Induced Toxicity

(2012) Áurea F. Castilho et al.   PLoS One

The bile salt export pump (BSEP) in health and disease

(2012) Ralf Kubitz et al.   Clinics and Research in Hepatology and Gastroenterology

Liver Dysfunction and Phosphatidylinositol-3-Kinase Signalling in Early Sepsis: Experimental Studies in Rodent Models of Peritonitis

(2012) Peter Recknagel et al.   PLOS MEDICINE

Remifentanil Preconditioning Reduces Hepatic Ischemia–Reperfusion Injury in Rats via Inducible Nitric Oxide Synthase Expression

(2011) Li-Qun Yang et al.   ANESTHESIOLOGY

Critical illness evokes elevated circulating bile acids related to altered hepatic transporter and nuclear receptor expression

(2011) Yoo-Mee Vanwijngaerden et al.   HEPATOLOGY

Impact of hypoxic hepatitis on mortality in the intensive care unit

(2011) Valentin Fuhrmann et al.   INTENSIVE CARE MEDICINE

Hypoxic hepatitis

(2011) Jean Henrion   LIVER INTERNATIONAL

Early versus Late Parenteral Nutrition in Critically Ill Adults

(2011) Michael P. Casaer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Drug-induced acute liver failure and gastrointestinal complications

(2010) Ishaq Lat et al.   CRITICAL CARE MEDICINE

Bile acids modulate glucocorticoid metabolism and the hypothalamic–pituitary–adrenal axis in obstructive jaundice

(2010) Alison D. McNeilly et al.   JOURNAL OF HEPATOLOGY

Postprandial plasma bile acid responses in normal weight and obese subjects

(2010) C. Glicksman et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events

(2009) Craig Lammert et al.   HEPATOLOGY

‘Liver function tests’ on the intensive care unit: a prospective, observational study

(2009) S. J. Thomson et al.   INTENSIVE CARE MEDICINE

Abnormal Liver Function in Relation to Hemodynamic Profile in Heart Failure Patients

(2009) V.M. van Deursen et al.   JOURNAL OF CARDIAC FAILURE

The Effect of Strict Blood Glucose Control on Biliary Sludge and Cholestasis in Critically Ill Patients

(2009) Dieter Mesotten et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

Circadian Dysregulation Disrupts Bile Acid Homeostasis

(2009) Ke Ma et al.   PLoS One

Poor outcome in progressive sclerosing cholangitis after septic shock

(2008) H. Kulaksiz et al.   ENDOSCOPY

Orphan receptor small heterodimer partner suppresses tumorigenesis by modulating cyclin D1 expression and cellular proliferation

(2008) Yuxia Zhang et al.   HEPATOLOGY

Targeting bile-acid signalling for metabolic diseases

(2008) Charles Thomas et al.   NATURE REVIEWS DRUG DISCOVERY

Liver histology in ICU patients dying from sepsis: A clinico-pathological study

(2008) John Koskinas et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Endocrine and paracrine role of bile acids

(2008) Verena Keitel et al.   WORLD JOURNAL OF GASTROENTEROLOGY