Non-monotonic cellular responses to heterogeneity in talin protein expression-level

MAP4K4 regulates integrin-FERM binding to control endothelial cell motility

(2015) Philip Vitorino et al.   NATURE

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Plasticity in the Macromolecular-Scale Causal Networks of Cell Migration

(2014) John G. Lock et al.   PLoS One

Noise Genetics: Inferring Protein Function by Correlating Phenotype with Protein Levels and Localization in Individual Human Cells

(2014) Shlomit Farkash-Amar et al.   PLoS Genetics

Vinculin Regulates the Recruitment and Release of Core Focal Adhesion Proteins in a Force-Dependent Manner

(2013) Alex Carisey et al.   CURRENT BIOLOGY

Diversity training for signal transduction: leveraging cell-to-cell variability to dissect cellular signaling, differentiation and death

(2013) Jesse W Cotari et al.   CURRENT OPINION IN BIOTECHNOLOGY

Two modes of integrin activation form a binary molecular switch in adhesion maturation

(2013) Ho-Sup Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Fer Protein-Tyrosine Kinase Promotes Lung Adenocarcinoma Cell Invasion and Tumor Metastasis

(2013) Joseph Ahn et al.   MOLECULAR CANCER RESEARCH

Integrin-dependent force transmission to the extracellular matrix by  -actinin triggers adhesion maturation

(2013) P. Roca-Cusachs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Network Crosstalk Dynamically Changes during Neutrophil Polarization

(2012) Chin-Jen Ku et al.   CELL

Assembly and disassembly of cell matrix adhesions

(2012) Bernhard Wehrle-Haller   CURRENT OPINION IN CELL BIOLOGY

Focal adhesion size uniquely predicts cell migration

(2012) Dong-Hwee Kim et al.   FASEB JOURNAL

United we stand – integrating the actin cytoskeleton and cell–matrix adhesions in cellular mechanotransduction

(2012) Ulrich S. Schwarz et al.   JOURNAL OF CELL SCIENCE

Dynamic Proteomics of Human Protein Level and Localization across the Cell Cycle

(2012) Shlomit Farkash-Amar et al.   PLoS One

The C terminus of talin links integrins to cell cycle progression

(2011) Pengbo Wang et al.   JOURNAL OF CELL BIOLOGY

Contributions of talin-1 to glioma cell-matrix tensional homeostasis

(2011) S. Sen et al.   Journal of the Royal Society Interface

Molecular Architecture and Function of Matrix Adhesions

(2011) B. Geiger et al.   Cold Spring Harbor Perspectives in Biology

Mechanotransduction In Vivo by Repeated Talin Stretch-Relaxation Events Depends upon Vinculin

(2011) Felix Margadant et al.   PLOS BIOLOGY

Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration

(2010) Margaret L. Gardel et al.   Annual Review of Cell and Developmental Biology

Cellular Heterogeneity: Do Differences Make a Difference?

(2010) Steven J. Altschuler et al.   CELL

Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation

(2010) Benjamin T Goult et al.   EMBO JOURNAL

Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1

(2010) Petra M. Kopp et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Systems microscopy: An emerging strategy for the life sciences

(2010) John G. Lock et al.   EXPERIMENTAL CELL RESEARCH

The NPIY motif in the integrin  1 tail dictates the requirement for talin-1 in outside-in signaling

(2010) B. Nieves et al.   JOURNAL OF CELL SCIENCE

Integrin-mediated Cell Attachment Induces a PAK4-dependent Feedback Loop Regulating Cell Adhesion through Modified Integrin αvβ5 Clustering and Turnover

(2010) Zhilun Li et al.   MOLECULAR BIOLOGY OF THE CELL

Biochemical and Structural Properties of the Integrin-Associated Cytoskeletal Protein Talin

(2009) David R. Critchley   Annual Review of Biophysics

Multiparametric analysis of focal adhesion formation by RNAi-mediated gene knockdown

(2009) Sabina E. Winograd-Katz et al.   JOURNAL OF CELL BIOLOGY

Integrins in cell migration - the actin connection

(2009) M. Vicente-Manzanares et al.   JOURNAL OF CELL SCIENCE

Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration

(2009) Cai Huang et al.   NATURE CELL BIOLOGY

Talin depletion reveals independence of initial cell spreading from integrin activation and traction

(2008) Xian Zhang et al.   NATURE CELL BIOLOGY

Cell–matrix adhesion complexes: Master control machinery of cell migration

(2007) John G. Lock et al.   SEMINARS IN CANCER BIOLOGY