Review
Oncology
Gabriel D. Ivey, Fabian M. Johnston, Nilofer S. Azad, Eric S. Christenson, Kelly J. Lafaro, Christopher R. Shubert
Summary: Colorectal cancer is one of the most common types of cancer, and at least half of patients diagnosed with it will develop metastatic liver disease. Surgical resection of colorectal liver metastases is considered potentially curative, but it is underutilized despite the availability of various operative strategies. Differing views on resectability may contribute to this underutilization.
Article
Oncology
Lana Bijelic, Isabel Ramos, Diane Goere
Summary: Important studies suggest that surgical resection of colorectal PM can be considered as a therapeutic option in appropriately selected patients, using standardized prognostic variables for evaluation. Current evidence does not support the use of specific HIPEC procedures in certain situations.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Giuseppe Malleo, Roberto Salvia, Laura Maggino, Giovanni Marchegiani, Michael D'Angelica, Ronald DeMatteo, Peter Kingham, Alessandra Pulvirenti, Elisabetta Sereni, William R. Jarnagin, Claudio Bassi, Peter J. Allen, Giovanni Butturini
Summary: This study focused on the long-term outcomes of pancreatectomy for pancreatic metastases from renal cell carcinoma and found that in selected patients with mostly isolated metachronous metastases, resection was associated with a high possibility of long-term disease control. The study observed a 10-year cumulative incidence of new RCC recurrence and disease-specific death, with certain risk factors such as synchronous metastases and extended pancreatectomy influencing recurrence and death rates. In patients with repeated recurrence, the cumulative incidence of RCC-related death was also noted.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Diego G. Vaz da Silva, Luis C. Bredt, Alessandro L. Diniz, Victor H. R. Vieira, Paulo H. S. Fernandes, Reitan Ribeiro, Heber S. C. Ribeiro, Alexandre F. Oliveira
Summary: The management of colorectal cancer liver metastasis has become complex with the increasing availability of medical, radiological, and surgical treatment options. However, surgical resection remains the only evidence-based curative therapy. These surgical standards by the Brazilian Surgical Oncology Society aim to guide clinicians in making evidence-based decisions regarding the modern surgical management of resectable CRLM within a multidisciplinary team.
JOURNAL OF SURGICAL ONCOLOGY
(2022)
Review
Oncology
Rony Maelle, Ratone Jean-Philippe, Walz Jochen, Pignot Geraldine, Caillol Fabrice, Pesenti Christian, Guerin Mathilde, Dermeche Slimane, Brunelle Serge, Salem Naji, Vicier Cecile, Rybikowski Stanislas, Maubon Thomas, Fakhfakh Sami, Tejeda Manuel, Giovannini Marc, Gravis Gwenaelle
Summary: This study conducted a retrospective analysis of mRCC patients between 2007 and 2019 at the Paoli-Calmettes Institute in Marseille, France, revealing the rarity but significance of digestive metastases from renal cell cancer. Most patients presented with gastrointestinal bleeding or anemia, and a combination of local and systemic treatments may improve survival rates.
FRONTIERS IN ONCOLOGY
(2021)
Review
Oncology
Min Sun, Hangliang Ding, Zhiqiang Zhu, Shengsheng Wang, Xinsheng Gu, Lingyun Xia, Tian Li
Summary: This study evaluated the effects of surgical treatments-based chemotherapy in the treatment of gastric cancer with liver metastases (GCLM). Results showed that HGCT and RFAG were more effective than other treatment options, with RFAG identified as the best option for overall survival and HGCT for 1-year survival rate. The study concluded that HGCT and RFAG have significant survival benefits for GCLM patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Gerardo Blanco-Fernandez, Constantino Fondevila-Campo, Alfonso Sanjuanbenito, Joan Fabregat-Prous, Luis Secanella-Medayo, Fernando Rotellar-Sastre, Fernando Pardo-Sanchez, Mikel Prieto-Calvo, Hector Marin-Ortega, Santiago Sanchez-Cabus, Luis Diez-Valladares, Oscar Alonso-Casado, Carmen Gonzalez-Serrano, Juan Carlos Rodriguez-Sanjuan, Gabriel Garcia-Plaza, Isabel Jaen-Torrejimeno, Miguel Angel Suarez-Munoz, Antonio Becerra-Massare, Paula Senra-del Rio, Elizabeth Pando, Rafael Lopez-Andujar, Elena Munoz-Forner, Mario Rodriguez-Lopez, Fernando Pereira, Alejandro Serrablo-Requejo, Victor Sanchez Turrion, Manuel Jimenez Garrido, Fernando Burdio, Elena Martin-Perez, Rafael Estevan-Estevan, Diego Lopez-Guerra, Jose Castell-Gomez, Javier Salinas-Gomez, Jose Angel Lopez-Baena, Santiago Lopez-Ben, Lorena Solar-Garcia, Alejandro J. Perez-Alonso, Luis Alberto Martinez-Insfran, Juan Luis Blas, Marian Cornejo, Alberto Gutierrez-Calvo, Carlos Domingo-del Pozo, Federico Ochando-Cerdan, Luis Munoz-Bellvis, Jose Rebollar-Saenz, Belinda Sanchez, Jose Maria Jover, Miguel Angel Gomez-Bravo, Jose M. Ramia, Adela Rojas-Holguin
Summary: This multicenter retrospective study evaluated the short and long-term outcomes of surgical treatment for renal cell carcinoma (RCC) pancreatic metastases. The results showed that pancreatic resection improved overall survival and disease-free survival in these patients, even if extrapancreatic metastases had been previously removed. Total pancreatectomy is not always necessary in cases of intrapancreatic multifocal compromise to improve survival.
Review
Urology & Nephrology
Pawel Rajwa, Takafumi Yanagisawa, Manuel Gruber, Axel Heidenreich, Steven Joniau, Alberto Briganti, Shahrokh F. Shariat, Giancarlo Marra, Giorgio Gandaglia
Summary: Despite the limitations, surgical metastasectomy can be a safe and feasible treatment option for selected patients with oligometastatic or oligorecurrent PCa. Although the evidence on survival benefit is inconclusive, it may lead to a prostate-specific antigen response and potential delay in systemic therapy for patients with oligometastatic PCa. Further prospective studies incorporating novel imaging techniques are necessary to establish the role of metastasectomy in metastatic PCa patients.
EUROPEAN UROLOGY FOCUS
(2023)
Article
Multidisciplinary Sciences
Arthur Wagner, Elena Haag, Ann-Kathrin Joerger, Philipp Jost, Stephanie E. Combs, Maria Wostrack, Jens Gempt, Bernhard Meyer
Summary: The management of patients with spinal metastases requires a multidisciplinary team approach, with surgical interventions playing a significant role in improving survival and functional status. The need for long-term symptom control and biomechanical stability underscores the importance of surgical strategies in the treatment algorithm.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
Satoshi Kato, Satoru Demura, Hideki Murakami, Katsuhito Yoshioka, Kazuya Shinmura, Noriaki Yokogawa, Takaki Shimizu, Norio Kawahara, Hiroyuki Tsuchiya
Summary: This study investigated postoperative survival and prognostic factors in 65 patients with metastatic renal cell carcinoma who underwent spinal metastasectomy. It found that complete metastasectomy, including extraspinal lesions, was associated with improved cancer-specific survival, while postoperative disability, liver metastasis, multiple spinal metastases, and incomplete metastasectomy were significant risk factors for short-term survival. Proper patient selection and complete metastasectomy can lead to better prognosis in these patients.
Article
Oncology
Chia-Te Yen, Wen-Jui Wu, Yen-Ting Chen, Wei-Chin Chang, Sheng-Hsiung Yang, Sheng-Yeh Shen, Jian Su, Hsuan-Yu Chen
Summary: Surgical resection of brain metastases in patients with NSCLC was found to significantly improve overall survival, especially in cases with large-sized metastases limited to the brain. The study concluded that the survival benefit of brain surgery was consistent regardless of EGFR mutation status.
AMERICAN JOURNAL OF CANCER RESEARCH
(2021)
Article
Oncology
Yuki Shimizu, Terumoto Koike, Toshiki Hasebe, Masaya Nakamura, Tatsuya Goto, Shin-ichi Toyabe, Masanori Tsuchida
Summary: This study aimed to investigate the risk factors for poor postoperative survival and recurrence in patients with NSCLC and nodal metastasis who were surgically treated and did not receive any induction treatments. Multiple-node metastases are risk factors for both poor survival and recurrence. Additional perioperative therapies may be required, especially in patients with squamous cell carcinoma.
Review
Oncology
Franz Sellner, Sabine Thalhammer, Martin Klimpfinger
Summary: Isolated pancreatic metastases of renal cell carcinoma is a rare form of metastasis with unique characteristics, including exclusive metastasis in the pancreas, a long interval between treatment and occurrence, frequent occurrence of isolated pancreatic metastases, and favorable prognosis after surgical therapy. The underlying genetic/epigenetic causes are not yet fully understood.
Article
Oncology
Saksham Gupta, Hassan Dawood, Alexandra Giantini Larsen, Luis Fandino, Erik H. Knelson, Timothy R. Smith, Eudocia Q. Lee, Ayal Aizer, Ian F. Dunn, Wenya Linda Bi
Summary: Brain metastases are the most common brain tumors in adults, whose management remains nuanced. A nationwide, multicenter analysis was conducted with a retrospective cohort of adult patients who received craniotomy for resection of brain metastasis. Results showed that frailty and infratentorial approach were associated with increased risks of reoperation before discharge, while pre-frailty and frailty were associated with increased odds for post-discharge mortality. An optimization of metrics contributing to patient frailty and heightened surveillance in patients with infratentorial metastases may be considered in the peri-operative period.
FRONTIERS IN ONCOLOGY
(2021)
Article
Clinical Neurology
Weitao Yao, Zhihuang Li, Liangyu Guo, Limin Niu, Yan Min, Xiaohui Niu
Summary: This study analyzed the efficacy and complications of spinal metastasis surgery for breast cancer, as well as the factors influencing survival and the predictive ability of current scoring systems. The results showed that spinal metastasis surgery for breast cancer has good efficacy and survival rates, with hormone-insensitive type and concomitant brain metastasis being independent risk factors for poor prognosis. The evaluation of the predictive model demonstrated that the SORG Web version can more accurately predict 1-year postoperative survival. This is important for guiding clinical decisions and treating patients with spinal metastasis from breast cancer.
WORLD NEUROSURGERY
(2022)
