Article
Clinical Neurology
Sisi Li, Jiani Chen, Yongqiao He, Yongyi Deng, Jie Chen, Wenyu Fang, Zhamu Zeren, Yadong Liu, Ammar Taha Abdullah Abdulaziz, Bo Yan, Dong Zhou
Summary: Patients with intracranial alveolar echinococcosis (IAE) exhibit distinct clinical and radiological characteristics, with common neurological symptoms such as headache and liver involvement. Surgical treatment remains a major challenge, and poor compliance with albendazole is a concern in the treatment of IAE.
FRONTIERS IN NEUROLOGY
(2021)
Article
Parasitology
Xuhui Zhang, Lamu Suolang, Yelei Ren, Yifei Wang, Yong Jiang, Xiaofei Zhong, Zehui Gou, Wu Zhou, Juan Chen, Yongzhong Li, Diming Cai
Summary: In this study, contrast-enhanced ultrasound (CEUS) was found to be more accurate than conventional ultrasound (US) in differentiating between cystic echinococcosis (CE) and alveolar echinococcosis (AE) in the liver. The accuracy rate for CEUS was 91.3%, while for US it was 65.2%. Therefore, CEUS can be considered a reliable tool for the differentiation of hepatic echinococcosis.
PARASITES & VECTORS
(2023)
Article
Parasitology
Qian Wang, Bo Zhong, Wenjie Yu, Guangjia Zhang, Christine M. Budke, Sha Liao, Wei He, Fan Chen, Kejun Xu, Fei Xie, Danbazeli, Qi Wang, Liu Yang, Yan Huang, Ruirui Li, Renxing Yao, Patrick Giraudoux, Philip S. Craig
Summary: Assessment of a control programme in Gansu province showed that deworming owned dogs can significantly reduce E. multilocularis infection in owned dogs and human AE prevalence, but did not have a significant impact on infection in wildlife intermediate hosts.
INTERNATIONAL JOURNAL FOR PARASITOLOGY
(2021)
Article
Nutrition & Dietetics
Qinxin Zheng, Yao Gong, Qian Wang, Chuan Jin, Qulian Guo, Mingcai Zeng, Yong Luo, Chumu Luorong, Cheng Li
Summary: The aim of this study was to examine the levels of vitamin A and selenium in children with echino-coccosis in Ganzi and Aba. Twenty-six children with cystic echinococcosis and 104 healthy controls were recruited. The results showed a significant decline in vitamin A levels and a high rate of selenium deficiency in the cases compared to the controls. The study suggests that children in high-risk areas should be given supplemental vitamin A and encouraged to consume a vitamin A-rich diet.
Article
Infectious Diseases
Wei He, Li-Ying Wang, Wen-Jie Yu, Guang-Jia Zhang, Bo Zhong, Sha Liao, Qi Wang, Rui-Rui Li, Liu Yang, Ren-Xin Yao, Yang Liu, Zeli Danba, Sheng-Chao Qin, Shi-An Wang, Yan-Xia Wang, Yan Huang, Qian Wang
Summary: The study investigated the prevalence and spatial distribution characteristics of human echinococcosis at the township level in Sichuan Province, China, revealing a spatial clustering of the disease. The high-high concentration areas were primarily located in some townships in the northwest of Sichuan Province, while the low-low concentration areas were predominantly located in some townships in the southeast of the province. The findings suggest that precise prevention and control strategies should be formulated for the clusters, specifically targeting the high-high clusters at the township level.
INFECTIOUS DISEASES OF POVERTY
(2021)
Article
Parasitology
Leonardo Uchiumi, Guillermo Mujica, Daniel Araya, Juan Carlos Salvitti, Mariano Sobrino, Sergio Moguillansky, Alejandro Solari, Patricia Blanco, Fabiana Barrera, Janete Lamunier, Marcos Arezo, Marcos Seleiman, Zaida E. Yadon, Francesca Tamarozzi, Adriano Casulli, Edmundo Larrieu
Summary: This study investigated the prevalence and risk factors of human cystic echinococcosis in Norquinco and Ramos Mexia, Argentina. Results suggest a link between infection acquired since childhood and constant exposure throughout life, especially in rural areas.
PARASITES & VECTORS
(2021)
Article
Microbiology
Deping Cao, Mingquan Pang, Defang Wu, Gen Chen, Xiaohong Peng, Kai Xu, Haining Fan
Summary: This study analyzed the gut microbiome composition of patients with alveolar echinococcosis (AE) and cystic echinococcosis (CE), and identified differences in the fecal bacteria between the patients and healthy individuals. The findings contribute to our understanding of the gut microbiome composition of AE and CE patients.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Parasitology
Tian Ma, Qian Wang, Mengmeng Hao, Chuizhao Xue, Xu Wang, Shuai Han, Qian Wang, Jiangshan Zhao, Xiao Ma, Xianglin Wu, Xiaofeng Jiang, Lei Cao, Yaming Yang, Yu Feng, Quzhen Gongsang, Juergen Scheffran, Liqun Fang, Richard James Maude, Canjun Zheng, Fangyu Ding, Weiping Wu, Dong Jiang
Summary: This study used the national echinococcosis survey data from 2012 to 2016 to investigate the spatial prevalence, demographic characteristics, and risk factors of cystic and alveolar echinococcosis in China. The results showed that female gender, older age, occupation as a herdsman or religious worker, and illiteracy were identified as risk factors for both types of echinococcosis. The prevalence of the diseases varied geographically, with high endemicity observed in the Tibetan Plateau region. Various environmental, biological, and social factors were found to be associated with the diseases. The findings will contribute to the development of targeted prevention measures and disease control strategies.
PARASITES & VECTORS
(2023)
Article
Infectious Diseases
Cao Deping, Jiang Bofan, Zhang Yaogang, Pang Mingquan
Summary: In this study, hsa-miR-125b-5p was found to be stably upregulated in the plasma and liver tissue samples from patients with AE, suggesting it may be a promising biomarker for early, non-invasive diagnosis of AE.
BMC INFECTIOUS DISEASES
(2021)
Article
Environmental Sciences
Jie Yin, Xiaoxu Wu, Jiatong Han, Paul Robert Torgerson
Summary: Through the analysis of environmental factors, this study found that minimum winter precipitation, percentage of grassland cover, and minimum elevation are linearly related to the incidence of human alveolar echinococcosis (AE). The relationship between maximum summer precipitation and AE is non-linear, with high incidence associated with moderate precipitation. Additionally, the interaction between maximum summer precipitation and number of patches of grassland also affects the incidence of human AE.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Multidisciplinary Sciences
Shuai Yan, Dong Wang, Junrui Zhang, Xiaojin Mo, Yu Feng, Liling Duan, Deyu Liu, Fan Li, Yongchun Dao, Ting Zhang, Wei Hu, Zheng Feng, Bin Zheng
Summary: The study in east Gansu province of China found that the prevalence of echinococcosis is associated with gender, age, and education level. The cross-sectional survey and prevalence surveillance both showed fluctuating rates of infection over different years.
SCIENTIFIC REPORTS
(2021)
Article
Parasitology
Zhenzhong Bai, Xiao Ma, Ranran Yan, Wen Lei, Yifan Zhang, Yanming Ren, Shou Liu
Summary: This study investigated the metabolic variations in patients with active and inactive hepatic alveolar echinococcosis (AE) and cystic echinococcosis (CE), and identified serum biomarkers that can differentiate between the two diseases. Active AE lesions strongly alter amino acid metabolism in the host, while CE lesions have an altered metabolism of oxidative stress response. These changes in metabolic pathways can serve as biomarkers for early diagnosis of AE and CE.
Article
Medical Informatics
Yongfeng Yang, Yangdan Cairang, Tian'an Jiang, Jianhua Zhou, Li Zhang, Baowen Qi, Shumei Ma, Lina Tang, Dong Xu, Lingdai Bu, Rui Bu, Xiang Jing, Hui Wang, Zubang Zhou, Cheng Zhao, Baoming Luo, Liwen Liu, Jianqin Guo, Yuzhen Nima, Guoyong Hua, Zengcheng Wa, Yuying Zhang, Guoyi Zhou, Wen Jiang, Changcheng Wang, Yang De, Xiaoling Yu, Zhigang Cheng, Zhiyu Han, Fangyi Liu, Jianping Dou, Hui Feng, Chong Wu, Ruifang Wang, Jie Hu, Qi Yang, Yanchun Luo, Jiapeng Wu, Haining Fan, Ping Liang, Jie Yu
Summary: This study aimed to develop a deep convolutional neural network (DCNN) model based on ultrasonography to identify and classify liver lesions, including echinococcosis. The results showed that the DCNN model demonstrated high accuracy and robustness in diagnosing echinococcosis and its types.
LANCET DIGITAL HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Yankai Chang, Yaqun Yan, Han Han, Yayun Wu, Jiakui Li, Changshen Ning, Sumei Zhang, Longxian Zhang
Summary: The study found Blastocystis infection in Tibetan sheep and Tibetan goats in Tibet, with ST10 subtype being dominant. Four subtypes were identified as zoonotic. Further research is needed to understand the role of humans, livestock, and wild animals in the spread of Blastocystis.
Article
Immunology
Fadime Eroglu, Mehmet Dokur, Yuksel Ulu
Summary: This study identified a miRNA profile that regulates T and B cell activity in patients with Alveolar and Cystic Echinococcosis, providing new insights into the early development mechanisms of these diseases.
PARASITE IMMUNOLOGY
(2021)
Article
Agronomy
Javier Fernandez-de-Simon, Michael Coeurdassier, Geoffroy Couval, Isabelle Fourel, Patrick Giraudoux
PEST MANAGEMENT SCIENCE
(2019)
Article
Biodiversity Conservation
Virgile Baudrot, Javier Fernandez-de-Simon, Michael Coeurdassier, Geoffroy Couval, Patrick Giraudoux, Xavier Lambin
JOURNAL OF APPLIED ECOLOGY
(2020)
Article
Entomology
Jens Jacob, Christian Imholt, Constantino Caminero-Saldana, Geoffroy Couval, Patrick Giraudoux, Silvia Herrero-Cofreces, Gyozo Horvath, Juan Jose Luque-Larena, Emil Tkadlec, Eddy Wymenga
JOURNAL OF PEST SCIENCE
(2020)
Article
Multidisciplinary Sciences
Pierre Galanaud, Anne Galanaud, Patrick Giraudoux, Henri Labesse
Article
Ecology
Corentin Nicod, Geoffroy Couval, Patrick Giraudoux, Francois Gillet
ACTA OECOLOGICA-INTERNATIONAL JOURNAL OF ECOLOGY
(2020)
Article
Multidisciplinary Sciences
Petra Villette, Eve Afonso, Geoffroy Couval, Aurelien Levret, Maxime Galan, Anne-Claude Goydadin, Jean-Francois Cosson, Patrick Giraudoux
SCIENTIFIC REPORTS
(2020)
Article
Infectious Diseases
Doudou Batumbo Boloweti, Patrick Giraudoux, Catherine Deniel, Emmanuel Garnier, Frederic Mauny, Celestin Mahinda Kasereka, Roger Kizungu, Jean Jacques Muyembe, Didier Bompangue, Gudrun Bornette
PLOS NEGLECTED TROPICAL DISEASES
(2020)
Article
Ecology
Patrick Giraudoux, Aurelien Levret, Eve Afonso, Michael Coeurdassier, Geoffroy Couval
ECOLOGY AND EVOLUTION
(2020)
Article
Ecology
Wajdi Zaatour, Nicolas Marilleau, Patrick Giraudoux, Nadege Martiny, Abdesslem Ben Haj Amara, Slimane Ben Miled
Summary: This study investigates the spread of zoonotic cutaneous leishmaniasis (ZCL) in Central Tunisia using an agent-based model (ABM) focusing on the movement of Meriones shawi (M.shawi). The research shows that the prevalence of the disease is closely related to rodent movement types and vegetation cover.
ECOLOGICAL MODELLING
(2021)
Article
Parasitology
Qian Wang, Bo Zhong, Wenjie Yu, Guangjia Zhang, Christine M. Budke, Sha Liao, Wei He, Fan Chen, Kejun Xu, Fei Xie, Danbazeli, Qi Wang, Liu Yang, Yan Huang, Ruirui Li, Renxing Yao, Patrick Giraudoux, Philip S. Craig
Summary: Assessment of a control programme in Gansu province showed that deworming owned dogs can significantly reduce E. multilocularis infection in owned dogs and human AE prevalence, but did not have a significant impact on infection in wildlife intermediate hosts.
INTERNATIONAL JOURNAL FOR PARASITOLOGY
(2021)
Article
Infectious Diseases
Sophie Molia, Juliette Saillard, Koussai Dellagi, Florence Cliquet, Jean-Mathieu Bart, Brice Rotureau, Patrick Giraudoux, Jean Jannin, Patrice Debre, Philippe Solano
Summary: The survey results show that One Health approaches are highly attractive to scientists in French-speaking tropical countries, but implementation is challenging due to various factors. Improvements in prevalence and economic data research, along with demonstrating the added value of One Health approaches, are key to increasing uptake. NTD networks play a crucial role in breaking down barriers and promoting collaboration among different sectors and disciplines.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Article
Biodiversity Conservation
Eve Afonso, Rong Fu, Amael Dupaix, Anne-Claude Goydadin, ZhongHua Yu, Dayong Li, Patrick Giraudoux, Li Li
Summary: The development of ecotourism may lead to subpopulations of wildlife becoming genetically structured and experiencing reduced genetic diversity, highlighting the need to strike a balance between conservation and tourism.
GLOBAL ECOLOGY AND CONSERVATION
(2021)
Article
Ecology
Monica E. Riojas-Lopez, Eric Mellink, Patrick Giraudoux
Summary: This study investigates the factors influencing bird and rodent assemblages in semi-arid rangelands in the southern Mexican Plateau. The results show that the condition of the rangelands and the seasons have different effects on the abundance and distribution of bird and rodent species. Shrub and nopal habitats are important components influencing the abundance of birds and rodents. Bird species turnover is higher than rodent species turnover, suggesting that birds have greater mobility to explore different patches of rangelands.
RANGELAND ECOLOGY & MANAGEMENT
(2022)
Article
Environmental Sciences
Christopher Marston, Clare Rowland, Aneurin O'Neil, Seth Irish, Francis Wat'senga, Pilar Martin-Gallego, Paul Aplin, Patrick Giraudoux, Clare Strode
Summary: Methods were developed to identify the biogeographical variables driving the abundance and distribution of three malaria vectors in the Democratic Republic of the Congo using Earth Observation (EO) data, mosquito monitoring captures, and Google Earth Engine. The results showed the importance of rainfall and land surface temperature in relation to mosquito abundance, as well as the coverage of forest and grassland. The developed method can provide a crucial tool for designing control programs and improving disease control activities to reduce malaria transmission.
Article
Multidisciplinary Sciences
Christopher Marston, Francis Raoul, Clare Rowland, Jean-Pierre Quere, Xiaohui Feng, Renyong Lin, Patrick Giraudoux
Summary: Small mammal species play a crucial role in various ecological processes and can have significant impacts on agricultural sectors and disease transmission. This study utilizes Earth observation data and on-site surveys to develop species distribution models for nine small mammal species in China and Kyrgyzstan. The models identify the key landscape variables driving species abundance and distributions, highlighting the optimal conditions for each species. The results improve our understanding of small mammal distributions and abundances, bridging the gap between human-defined and species-defined perspectives of optimal habitat.
Article
Parasitology
Gabriela Martinez Moura Tavares, Hannar Angelica de Melo Alverga, Estela Moraes Felix, Giovana de Oliveira Dichman, Gabriel Monteiro Pinheiro, Yara Juliano, Priscila Paruci, Dennis Minoru Fujita, Lucas Melo Neves, Marina Tiemi Shio, Luiz Henrique da Silva Nali
Summary: This study investigated the frequency of N. gonorrhoeae infection in women in a poor area of São Paulo and found that most of the strains detected showed resistance to one or more antimicrobials.
Article
Parasitology
Qian Yao, Ying-Ying Fan, Shuang Huang, Gui-Rong Hu, Jun-Ke Song, Xin Yang, Guang-Hui Zhao
Summary: This study found that the expression of miR-4521 was upregulated during C. parvum infection, and this upregulation was related to the TLR/NF-kappa B signal pathway. Additionally, miR-4521 promoted the propagation of C. parvum in HCT-8 cells by regulating BCL2-mediated cell apoptosis through targeting foxm1.
Article
Parasitology
Cho Naing, Maxine A. Whittaker, Wong Siew Tung, Htar Aung, Joon Wah Mak
Summary: This study aimed to estimate the prevalence of zoonotic brugian filariasis in animals and compare it with the prevalence in humans in the same area. The findings suggest that cats, dogs, and leaf-eating monkeys may serve as potential reservoirs for human brugian filariasis.
Review
Parasitology
Raissa Nogueira de Brito, Susan Tanner, Julie Velasquez Runk, Juliana Hoyos
Summary: This study conducted a scoping review to identify major research themes and knowledge gaps in the social science literature on leishmaniases or Chagas disease. The findings showed that research in this field mainly focuses on the sociocultural, economic, historical, and political dimensions of the diseases. Future research should pay more attention to how social institutions and economic factors shape disease education, control measures, healthcare access, and quality of life of affected individuals.
Article
Parasitology
Minghao Zheng, Mengyao Zhang, Hao Li, Shipo Wu, Yuee Zhao, Jinlong Zhang, Yunyue Zhou, Mohamed Boie Jalloh, Kun Zhang, Lina Chen, Zhiqiang Mi, Yong Cui, Lihua Hou
Summary: Rapid and convenient detection of Plasmodium falciparum, the deadliest malaria parasite in Africa, is crucial for malaria eradication efforts in medical resource-limited settings. A CRISPR-based diagnostic method that can detect P. falciparum without nucleic acid extraction was developed and showed high sensitivity and consistency with qPCR test. It can also detect artemisinin-resistant strains and other laboratory-cultured strains. This method has great potential for clinical testing and large-scale community screening in Africa and other regions.
Article
Parasitology
Fabian Correa-Morales, Cassandra Gonzalez-Acosta, David Ibarra-Ojeda, Miguel Moreno-Garcia
Summary: Since 2002, West Nile Virus (WNV) has been reported in 18 states in Mexico. This paper discusses the proposed hypotheses for the absence of WNV outbreaks in Latin America and provides a context-specific explanation for Mexico.
Article
Parasitology
Umberto Molini, Lauren M. Coetzee, Vernon Christians, Maria Y. Hemberger, Bernard Chiwome, Maria Amukwaya, Siegfried Khaiseb, Giovanni Cattoli, William G. Dundon, Giovanni Franzo
Summary: Porcine circovirus 3 (PCV-3) has been reported globally since its first identification in 2015. Limited data on PCV-3 in Africa led to a study in Namibia, which found a high prevalence of PCV-3 in backyard piggeries, but not in commercial farms with higher biosecurity measures. The source of viral introduction and factors such as semen importation, feeding backyard pigs with human food waste, pig exchanges, and wildlife movements may be involved in the dispersal of PCV-3 within Namibia. Further studies are needed to understand the epidemiology and impact of PCV-3 on pig productivity and wildlife health.
Article
Parasitology
Chutchai Piewbang, Panida Poonsin, Pattiya Lohavicharn, Panitnan Punyathi, Sawang Kesdangsakonwut, Tanit Kasantikul, Somporn Techangamsuwan
Summary: This study provides insights into the pathology of natural SARS-CoV-2 infection in dogs, revealing severe damage to the lungs and involvement of multiple organs. The findings suggest the potential utility of dogs as a model for studying SARS-CoV-2 infection in humans, highlighting the need for further investigation.
Article
Parasitology
Julian Avila-Jimenez, Juan David Gutierrez, Mariano Altamiranda-Saavedra
Summary: Leishmaniasis is a parasitic disease transmitted to humans by sandfly vectors and vertebrate hosts. This study used ecological niche modeling to investigate the potential distribution of host and vector species associated with cutaneous leishmaniasis transmission, revealing different distribution patterns under varying climatic conditions.
Article
Parasitology
Luis A. Gomez-Puerta, Juan Olazabal, Santiago Paredes, Juan Lopez, Miguel Anampa, Angelica Mondragon, Ana Vargas-Calla, Hugo Castillo
Summary: This study reports the first detection of Candidatus M. haemolamae infection in vicunas from the Pampa Galeras National Reserve in Peru, using molecular diagnosis. Tick-infested vicunas had a higher likelihood of being infected with Candidatus M. haemolamae compared to tick-free vicunas. Gender and age were not associated with infection.
Article
Parasitology
Berlin Londono-Renteria, Zakaria Seidu, Helena Lamptey, Michael F. Ofori, Lars Hviid, Mary Lopez-Perez
Summary: Heterozygous carriers of HbAS and HbAC have a reduced risk of severe malaria, but not immunity against Plasmodium falciparum infection. Antibody levels against gSG6-P1 peptide in Anopheles mosquito saliva can serve as a serological biomarker for exposure to Plasmodium infection. This study highlights the importance of studying the role of hemoglobinopathies in malaria transmission for improving control interventions.
Article
Parasitology
Imane Belbacha, Meryem El Azzouzi, Rajae Bensghir, Kamal Filali Marhoum, Khadija Hajjout, El Mir Elharti, Khalid Sadki, Hicham Oumzil
Summary: This study investigates the association of three SNPs in the APOBEC3G gene with disease outcomes in Moroccan HIV-1 infected patients. The rs2294367 CG genotype is strongly associated with protection against HIV-1 infection, particularly in older individuals.
Article
Parasitology
Tan Luong, Do Kien Tran, Anh Hung Pham, Thi Thu-Ha Hoang, Van Khang Pham, Quang Thai Pham, Thi Mai Hung Tran, Minh Hoa Luong, Thanh Long Pham, Jason K. Blackburn
Summary: This study examined the epidemiology of anthrax in Lai Chau province, Vietnam, using historical data. Spatial clusters of human and livestock anthrax were identified, and the characteristics of the disease were described. The study found that there were distinct differences between the high-risk areas for human and livestock anthrax, and most human cases occurred during specific seasons. Additionally, the decrease in livestock anthrax vaccine coverage was associated with an increase in disease incidence.
Article
Parasitology
Jin-tao Chen, Jian-bo Zhan, Ming-chao Zhu, Kai-ji Li, Man-qing Liu, Bin Hu, Kun Cai, Hai-rong Xiong, Shu-liang Chen, Wei-long Tan, Liang-jun Chen, Wei Hou
Summary: This study investigated the prevalence and variation of orthohantavirus in rodents and humans in Hubei province, China. It identified the diversity of orthohantaviruses circulating in the region, with the HV004-like subtype being the main genotype in rodents and patients. This highlights the importance of continued attention and research on orthohantaviruses, especially newly identified strains.