Combined hydroxyurea and ETA receptor blockade reduces renal injury in the humanized sickle cell mouse

Beneficial Effect of Low Fixed Dose of Hydroxyurea in Vaso-occlusive Crisis and Transfusion Requirements in Adult HbSS Patients: A Prospective Study in a Tertiary Care Center

(2017) Sudha Sethy et al.   INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION

Endothelin ET A Receptor Blockade, by Activating ET B Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention

(2017) Magali Vercauteren et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Long-Term Endothelin-A Receptor Antagonism Provides Robust Renal Protection in Humanized Sickle Cell Disease Mice

(2017) Malgorzata Kasztan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Changes in urine albumin to creatinine ratio with the initiation of hydroxyurea therapy among children and adolescents with sickle cell disease

(2017) Sarah Tehseen et al.   PEDIATRIC BLOOD & CANCER

Beneficial Effect of Low Fixed Dose of Hydroxyurea in Vaso-occlusive Crisis and Transfusion Requirements in Adult HbSS Patients: A Prospective Study in a Tertiary Care Center

(2017) Sudha Sethy et al.   Indian Journal of Hematology and Blood Transfusion

Endothelin receptor-specific control of endoplasmic reticulum stress and apoptosis in the kidney

(2017) Carmen De Miguel et al.   Scientific Reports

Inflammatory and oxidative stress phenotypes in transgenic sickle cell mice

(2016) Emmanuelle Charrin et al.   BLOOD CELLS MOLECULES AND DISEASES

Endothelin-1 contributes to the progression of renal injury in sickle cell disease via reactive oxygen species

(2015) J Brett Heimlich et al.   BRITISH JOURNAL OF PHARMACOLOGY

Break-seq reveals hydroxyurea-induced chromosome fragility as a result of unscheduled conflict between DNA replication and transcription

(2015) Elizabeth A. Hoffman et al.   GENOME RESEARCH

Six Months of Hydroxyurea Reduces Albuminuria in Patients with Sickle Cell Disease

(2015) P. Bartolucci et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sickle cell disease: renal manifestations and mechanisms

(2015) Karl A. Nath et al.   Nature Reviews Nephrology

Hydroxyurea in Sickle Cell Disease: Drug Review

(2013) Rohit Kumar Agrawal et al.   INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION

Hydroxyurea is associated with lower prevalence of albuminuria in adults with sickle cell disease

(2013) L.-P. Laurin et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Vasculature and Kidney Complications in Sickle Cell Disease

(2012) K. A. Nath et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Distinct Actions of Endothelin A-Selective Versus Combined Endothelin A/B Receptor Antagonists in Early Diabetic Kidney Disease

(2011) M. A. Saleh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1This article is one of a selection of papers published in the two-part special issue entitled 20 Years of Endothelin Research.

(2010) N.F. Kelland et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model

(2010) J. D. Lebensburger et al.   HAEMATOLOGICA

Sickle-cell disease

(2010) David C Rees et al.   LANCET

Hydroxycarbamide-induced changes in E/beta thalassemia red blood cells

(2008) Sylvia T. Singer et al.   AMERICAN JOURNAL OF HEMATOLOGY

Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease

(2008) Nathalie Sabaa et al.   JOURNAL OF CLINICAL INVESTIGATION

Magnetic resonance detection of kidney iron deposition in sickle cell disease: A marker of chronic hemolysis

(2008) Aaron Schein et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Trends in Pediatric Sickle Cell Disease-Related Mortality in the United States, 1983-2002

(2008) Emad Yanni et al.   JOURNAL OF PEDIATRICS

Hydroxyurea for Children with Sickle Cell Disease

(2008) Matthew M. Heeney et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Kidney Injury Molecule‐1 (KIM‐1): A specific and sensitive biomarker of kidney injury

(2008) Joseph V. Bonventre   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION