Current understanding of increased insulin sensitivity after exercise - emerging candidates

Mice with AS160/TBC1D4-Thr649Ala Knockin Mutation Are Glucose Intolerant with Reduced Insulin Sensitivity and Altered GLUT4 Trafficking

(2011) Shuai Chen et al.   Cell Metabolism

In vivo exercise followed by in vitro contraction additively elevates subsequent insulin-stimulated glucose transport by rat skeletal muscle

(2010) Katsuhiko Funai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle

(2010) Kanokwan Vichaiwong et al.   BIOCHEMICAL JOURNAL

Mechanisms of Insulin Resistance After Insulin-Induced Hypoglycemia in Humans: The Role of Lipolysis

(2010) P. Lucidi et al.   DIABETES

TBC1D1 Regulates Insulin- and Contraction-Induced Glucose Transport in Mouse Skeletal Muscle

(2010) D. An et al.   DIABETES

Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training

(2010) B. F. Vind et al.   DIABETOLOGIA

Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma

(2010) Shuji Ueda et al.   FASEB JOURNAL

Exercise-induced TBC1D1 Ser237 phosphorylation and 14-3-3 protein binding capacity in human skeletal muscle

(2010) Christian Frøsig et al.   JOURNAL OF PHYSIOLOGY-LONDON

AMP-activated protein kinase in contraction regulation of skeletal muscle metabolism: necessary and/or sufficient?

(2009) T. E. Jensen et al.   Acta Physiologica

Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle

(2009) Jonas T. Treebak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Increased AS160 phosphorylation, but not TBC1D1 phosphorylation, with increased postexercise insulin sensitivity in rat skeletal muscle

(2009) Katsuhiko Funai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle

(2009) Christian Pehmøller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC

(2009) M. P. Sajan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Muscle Contraction, but Not Insulin, Increases Microvascular Blood Volume in the Presence of Free Fatty Acid-Induced Insulin Resistance

(2009) A. C. Inyard et al.   DIABETES

Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle

(2009) J. T. Treebak et al.   DIABETOLOGIA

Infusing Lipid Raises Plasma Free Fatty Acids and Induces Insulin Resistance in Muscle Microvasculature

(2009) Zhenqi Liu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia

(2009) S. Dash et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired microvascular perfusion: a consequence of vascular dysfunction and a potential cause of insulin resistance in muscle

(2008) Michael G. Clark   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

(2008) Kei Sakamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

(2008) Shuai Chen et al.   BIOCHEMICAL JOURNAL

Activation of the small GTPase Rac1 by a specific guanine-nucleotide-exchange factor suffices to induce glucose uptake into skeletal-muscle cells

(2008) Shuji Ueda et al.   BIOLOGY OF THE CELL

GLUT4 Vesicle Recruitment and Fusion Are Differentially Regulated by Rac, AS160, and Rab8A in Muscle Cells

(2008) Varinder K. Randhawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle

(2008) Eric B. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY