The Wnt/Frizzled pathway as a therapeutic target for cardiac hypertrophy: where do we stand?

Wnt/frizzled signalling modulates the migration and differentiation of immortalized cardiac fibroblasts

(2010) Hilde Laeremans et al.   CARDIOVASCULAR RESEARCH

WNT Signaling in Adult Cardiac Hypertrophy and Remodeling

(2010) Martin W. Bergmann   CIRCULATION RESEARCH

Wnt Signaling Is Critical for Maladaptive Cardiac Hypertrophy and Accelerates Myocardial Remodeling

(2010) Pratima Malekar et al.   HYPERTENSION

Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction

(2010) W. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Catenin/TCF/LEF1 can directly regulate phenylephrine-induced cell hypertrophy and Anf transcription in cardiomyocytes

(2009) Chen-Guang Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mouse strain determines the outcome of wound healing after myocardial infarction

(2009) Susanne W.M. van den Borne et al.   CARDIOVASCULAR RESEARCH

CaMKII Negatively Regulates Calcineurin–NFAT Signaling in Cardiac Myocytes

(2009) Scott M. MacDonnell et al.   CIRCULATION RESEARCH

Myocardial remodeling after infarction: the role of myofibroblasts

(2009) Susanne W. M. van den Borne et al.   Nature Reviews Cardiology

Molecular targets and regulators of cardiac hypertrophy

(2009) Agrawal Rohini et al.   PHARMACOLOGICAL RESEARCH

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis

(2008) P H Sugden et al.   BRITISH JOURNAL OF PHARMACOLOGY

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

(2008) P. Bovolenta et al.   JOURNAL OF CELL SCIENCE

 -Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation

(2008) L. C. Zelarayan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Wnt/frizzled/GSK-3β pathway: a novel therapeutic target for cardiac hypertrophy

(2008) W BLANKESTEIJN et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation

(2007) Michael Hendricks et al.   MOLECULAR AND CELLULAR NEUROSCIENCE