Article
Engineering, Environmental
Yuan Cheng, Xin Li, Ming-Ya Fang, Qing-Jing Ye, Zhi-Miao Li, Golam Jalal Ahammed
Summary: The application of EECCG alleviated the adverse effects of cadmium stress in tomato plants by reducing oxidative stress and promoting the expression of RBOH1 gene. These findings contribute to our understanding of the stress resistance properties of EGCG in plants.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Xiaowei Zhang, Yanyan Zhang, Chenxiao Xu, Kun Liu, Huangai Bi, Xizhen Ai
Summary: The study showed that exogenous H2O2 and IAA significantly improved chilling tolerance in cucumber seedlings, with IAA-induced tolerance being regulated by H2O2. Endogenous synthesis of H2O2 was enhanced by IAA, while H2O2 had minimal effects on endogenous IAA levels in cucumber seedlings.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Shraddha Gang, Sheetal Sharma, Meenu Saraf, Martin Buck, Jorg Schumacher
Summary: Inoculating barley and chickpea with Klebsiella strains capable of producing auxin significantly increased nitrogen use efficiency and nitrogen uptake efficiency, leading to reduced nitrogen fertilizer application. The study showed that the enhanced root surface area contributed to the improved nitrogen acquisition in the plants, with the auxin producers outperforming the non-auxin producer in terms of NUE and NUpE.
Article
Biochemistry & Molecular Biology
Lubica Liptakova, Loriana Demecsova, Katarina Valentovicova, Veronika Zelinova, Ladislav Tamas
Summary: Short-term Cd treatment induces changes in gene expression in barley root tips via IAA and ROS signaling during mild and severe Cd stress. The early activation of MYB1 transcription factor expression is partially regulated by auxin signaling in mildly stressed seedlings. Alterations in gene expression in response to Cd stress are related to IAA and ROS levels in the cells.
PLANT MOLECULAR BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Warin Rangubpit, Eukote Suwan, Danai Sangthong, Kannika Wongpanit, Roger W. Stich, Prapasiri Pongprayoon, Sathaporn Jittapalapong
Summary: In this study, molecular dynamics simulations were conducted to investigate the binding of GTX and GSH to RmGST. It was found that GSH binds tighter and sits rigidly inside the G-site, while GTX occupies both active sites.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Xingang Li, Yuanting Pang, Yiwang Zhong, Zhandong Cai, Qibin Ma, Ke Wen, Hai Nian
Summary: In this study, a tau-like glutathione transferase family gene named GmGSTU23 was identified in soybean, which showed a concentration-time-specific expression pattern in response to salt stress. Transgenic lines with GmGSTU23 displayed enhanced salt tolerance, root length, and fresh weight compared to the wild type. Changes in glutathione pools and associated enzyme activity were observed, indicating that GmGSTU23 enhances the activity of glutathione transferase to scavenge reactive oxygen species and glutathione, thereby conferring enhanced tolerance to salt stress in plants.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Liwen Cui, Yu Chen, Jun Liu, Qiang Zhang, Lei Xu, Zhimin Yang
Summary: Cadmium (Cd) is a highly toxic metal that poses serious threats to both plant growth and human health. Hence, it is crucial to explore simple, practical, and eco-friendly methods to mitigate its toxicity. Previous research has mainly focused on the physiological and biochemical aspects of zinc sulfate application for enhancing plant tolerance to Cd, with insufficient investigation into the underlying molecular mechanisms. In this study, high and low concentrations of zinc sulfate were sprayed on seashore paspalum plants under Cd stress, and transcriptome sequencing and physiological indicators were employed to elucidate the mechanisms of Cd tolerance.
Article
Agronomy
Yushi Jiang, Yuzhe Zhang, Ruijie Duan, Jiayi Fan, Peng Jiao, Hongji Sun, Shuyan Guan, Siyan Liu
Summary: ZmGST26 was found to be downregulated in maize under drought stress. Overexpression of ZmGST26 in Arabidopsis resulted in increased sensitivity to drought stress and ABA, as well as inhibited ABA-mediated stomatal closure. ZmGST26 overexpression decreased the resistance of Arabidopsis to drought stress and led to the accumulation of reactive oxygen species.
Article
Neurosciences
Bo Cheng, Xiaoliang Hong, Linfang Wang, Yuanyuan Cao, Dengli Qin, Han Zhou, Dianshuai Gao
Summary: Curzerene inhibits the progression of glioma by suppressing the expression of GSTA4 and matrix metalloproteinase 9, and inhibiting the activation of the mTOR pathway. It also induces apoptosis and reduces invasion and migration of glioma cells. In vivo studies have shown that Curzerene significantly inhibits tumor growth and prolongs survival time.
CNS NEUROSCIENCE & THERAPEUTICS
(2022)
Article
Environmental Sciences
Chotinan Junpradit, Patsaraporn Thooppeng, Kannika Duangmal, Benjaphorn Prapagdee
Summary: This study demonstrated that Streptomyces rapamycinicus and Streptomyces cyaneus could enhance plant growth and cadmium uptake in Chlorophytum comosum, showing potential for phytoremediation of cadmium-polluted soil.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Editorial Material
Biochemistry & Molecular Biology
Tiffany M. Russell, Des R. Richardson
Summary: GSTs are versatile proteins that play important roles in detoxification and cellular nitric oxide metabolism. They have the ability to convert organic nitrates into nitric oxide, thereby regulating vasodilation. GSTs are also considered suitable targets for pharmaceutical development, particularly in the field of anti-cancer drugs.
Article
Biochemistry & Molecular Biology
Jing Yan, Hengsen Zhang, Yuna Tomochika, Bin Chen, Yashuang Ping, Md. Shoriful Islam, Shuhei Aramaki, Tomohito Sato, Yu Nagashima, Tomohiko Nakamura, Tomoaki Kahyo, Daita Kaneda, Kenji Ogawa, Minoru Yoshida, Mitsutoshi Setou
Summary: This study reveals that silencing MGST3 downregulates the interaction between UBL3 and alpha-syn, which has implications for clearing excess alpha-syn and the pathology of neurodegenerative diseases.
Article
Microbiology
Alvaro de Obeso Fernandez del Valle, Christian Quintus Scheckhuber, David Armando Chavaro-Perez, Erandi Ortega-Barragan, Sutherland K. Maciver
Summary: Some members of Acanthamoeba are facultative pathogens that can infect the cornea, causing Acanthamoeba keratitis. During encystation, there is an upregulation of glutathione S-transferase (GST) genes, which play a role in maintaining redox balance. Inhibiting GST with ethacrynic acid decreases cell viability by 70%. Targeting GST and associated processes could be a potential treatment strategy to reduce relapses of Acanthamoeba infection.
Article
Plant Sciences
Jasim Basheer, Pavol Vadovic, Olga Samajova, Pavol Melicher, George Komis, Pavel Krenek, Michaela Kralova, Tibor Pechan, Miroslav Ovecka, Tomas Takac, Jozef Samaj
Summary: Through TALEN-based knockout of HvMPK3, barley roots gain resistance against Fusarium root rot, possibly by inhibiting hyphal penetration, mitigating ROS production, and enhancing suberin accumulation in the root cell wall.
Article
Plant Sciences
Georgina Pesti-Asboth, Piroska Molnar-Birone, Ildiko Forgacs, Judit Remenyik, Judit Dobranszki
Summary: Melatonin, an ancient hormone, plays a prominent role in the growth and development of plants. This study investigated the relationship between endogenous melatonin and the antioxidant system in potato plants under ultrasound stress. Results showed that ultrasound stress activated the defense system and decreased melatonin levels. Melatonin provided protection against membrane damage caused by ultrasound treatment. It acts as a key component in regulating various biochemical, cellular, and physiological responses.
FRONTIERS IN PLANT SCIENCE
(2022)