IL-6 trans-signaling increases expression of airways disease genes in airway smooth muscle

Interleukin-6 inhibition for treatment of rheumatoid arthritis: A review of tocilizumab therapy

(2016) Aarat Patel et al.   Drug Design Development and Therapy

TheNAMPTPromoter Is Regulated by Mechanical Stress, Signal Transducer and Activator of Transcription 5, and Acute Respiratory Distress Syndrome–Associated Genetic Variants

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CCL11 as a potential diagnostic marker for asthma?

(2014) Dandan Wu et al.   JOURNAL OF ASTHMA

Baseline KL-6 predicts increased risk for acute exacerbation of idiopathic pulmonary fibrosis

(2014) Shinichiro Ohshimo et al.   RESPIRATORY MEDICINE

Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study

(2013) Iain B McInnes et al.   ANNALS OF THE RHEUMATIC DISEASES

Clinical Significance and Prognostic Value of Pentraxin-3 as Serologic Biomarker for Lung Cancer

(2013) Dai Zhang et al.   Asian Pacific Journal of Cancer Prevention

Nicotinamide N-methyltransferase in Non-small Cell Lung Cancer: Promising Results for Targeted Anti-cancer Therapy

(2013) Davide Sartini et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

VEGFA variants are associated with pre-school lung function, but not neonatal lung function

(2013) E. Kreiner-Møller et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Targeted therapy for non-small-cell lung cancer: past, present and future

(2013) Patrick M Forde et al.   Expert Review of Anticancer Therapy

Proteolytic cleavage of the long pentraxin PTX3 in the airways of cystic fibrosis patients

(2013) Yveline Hamon et al.   Innate Immunity

Prototypic Long Pentraxin PTX3 Is Present in Breast Milk, Spreads in Tissues, and Protects Neonate Mice from Pseudomonas aeruginosa Lung Infection

(2013) S. Jaillon et al.   JOURNAL OF IMMUNOLOGY

Pentraxin 3 (PTX3) Is Associated with Severe Sepsis and Fatal Disease in Emergency Room Patients with Suspected Infection: A Prospective Cohort Study

(2013) Raija Uusitalo-Seppälä et al.   PLoS One

Association between SOD2 C47T polymorphism and lung cancer susceptibility: a meta-analysis

(2013) Na Li et al.   TUMOR BIOLOGY

Pentraxin 3: An Immuno-Regulator in the Lungs

(2013) Jyoti Balhara et al.   Frontiers in Immunology

Cadmium-mediated toxicity of lung epithelia is enhanced through NF-κB-mediated transcriptional activation of the human zinc transporter ZIP8

(2012) Jessica R. Napolitano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Sphingosine-1–Phosphate Receptor–3 Is a Novel Biomarker in Acute Lung Injury

(2012) Xiaoguang Sun et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Airway Smooth Muscle in Asthma

(2012) Judith L. Black et al.   CLINICS IN CHEST MEDICINE

Vascular Endothelial Growth Factor as a Key Inducer of Angiogenesis in the Asthmatic Airways

(2012) Norbert Meyer et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Expression of eotaxins in the material from nasal brushing in asthma, allergic rhinitis and COPD patients

(2012) Magdalena Paplińska et al.   CYTOKINE

The IL6R variation Asp358Ala is a potential modifier of lung function in subjects with asthma

(2012) Gregory A. Hawkins et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Knockdown of secretory phospholipase A2 IIa reduces lung cancer growth in vitro and in vivo

(2012) Jessica A. Yu et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Protective effects of long pentraxin PTX3 on lung injury in a severe acute respiratory syndrome model in mice

(2012) Bing Han et al.   LABORATORY INVESTIGATION

Asthma Treatment Outcome in Children Is Associated with Vascular Endothelial Growth Factor A (VEGFA) Polymorphisms

(2012) Mateja Balantic et al.   Molecular Diagnosis & Therapy

Pentraxin 3 (PTX3) Expression in Allergic Asthmatic Airways: Role in Airway Smooth Muscle Migration and Chemokine Production

(2012) Jingbo Zhang et al.   PLoS One

Pro-inflammatory and immunomodulatory functions of airway smooth muscle: Emerging concepts

(2012) Yuxiu C. Xia et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Role of plasma bactericidal/permeability-increasing protein, group IIA phospholipase A2, C-reactive protein, and white blood cell count in the early detection of severe sepsis in the emergency department

(2012) Raija Uusitalo-Seppälä et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Surfactant protein B inhibits secretory phospholipase A2 hydrolysis of surfactant phospholipids

(2011) R. Duncan Hite et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Secretory Phospholipase A2-Mediated Depletion of Phosphatidylglycerol in Early Acute Respiratory Distress Syndrome

(2011) David L. Long et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

The apelinergic system in the developing lung: Expression and signaling

(2011) Paulina Piairo et al.   PEPTIDES

Genes and Gene Ontologies Common to Airflow Obstruction and Emphysema in the Lungs of Patients with COPD

(2011) Santiyagu M. Savarimuthu Francis et al.   PLoS One

Early detection of severe sepsis in the emergency room: Diagnostic value of plasma C-reactive protein, procalcitonin, and interleukin-6

(2011) Raija Uusitalo-Seppälä et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Genetic variation in GREM1 is a risk factor for fibrosis in pulmonary sarcoidosis

(2011) M. Heron et al.   TISSUE ANTIGENS

Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-κB

(2010) Shengying Bao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Apelin Attenuates Hyperoxic Lung and Heart Injury in Neonatal Rats

(2010) Yvonne P. de Visser et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers

(2010) Kristy L. Richards et al.   CANCER

Is Interleukin-6 Receptor Blockade the Holy Grail for Inflammatory Diseases?

(2010) M A Febbraio et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Apelin Expression in Human Non-small Cell Lung Cancer: Role in Angiogenesis and Prognosis

(2010) Judit Berta et al.   Journal of Thoracic Oncology

Sputum IL-6 concentrations in severe asthma and its relationship with FEV1

(2010) J. B. Morjaria et al.   THORAX

Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease

(2009) B. Beghé et al.   ALLERGY

Interleukin-6 Trans-Signaling and Colonic Cancer Associated with Inflammatory Bowel Disease

(2009) Stefan Rose-John et al.   CURRENT PHARMACEUTICAL DESIGN

Associations of IL6 polymorphisms with lung function decline and COPD

(2009) J-Q He et al.   THORAX

The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia

(2008) Beth Besecker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

MUC1 Mucin

(2008) K. Chul Kim et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Glucocorticoid- and Protein Kinase A–Dependent Transcriptome Regulation in Airway Smooth Muscle

(2008) Anna M. Misior et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hypoxia-Induced Apelin Expression Regulates Endothelial Cell Proliferation and Regenerative Angiogenesis

(2008) Mélanie Eyries et al.   CIRCULATION RESEARCH

Hypoxia upregulates the expression of angiopoietin-like-4 in human articular chondrocytes: Role of angiopoietin-like-4 in the expression of matrix metalloproteinases and cartilage degradation

(2008) Minako Murata et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Association of IL-6 gene polymorphisms and COPD in a Spanish Population

(2008) Elizabeth Córdoba-Lanús et al.   RESPIRATORY MEDICINE

Hypoxia, angiogenesis, and lung cancer

(2008) Ranjit K. Goudar et al.   Current Oncology Reports