MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 cells in vitro by regulating LDLR and PCSK9 expression

Danthron activates AMP-activated protein kinase and regulates lipid and glucose metabolism in vitro

(2013) Rong Zhou et al.   ACTA PHARMACOLOGICA SINICA

Potential of Proprotein Convertase Subtilisin/Kexin Type 9 Based Therapeutics

(2013) Evan A. Stein et al.   Current Atherosclerosis Reports

Attenuation of Early Atherogenesis in Low-Density Lipoprotein Receptor–Deficient Mice by Proteasome Inhibition

(2012) Nicola Wilck et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Proteasome Inhibitor-stimulated Nrf1 Protein-dependent Compensatory Increase in Proteasome Subunit Gene Expression Reduces Polycomb Group Protein Level

(2012) Sivaprakasam Balasubramanian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 in combination with a statin in patients with hypercholesterolaemia (LAPLACE-TIMI 57): a randomised, placebo-controlled, dose-ranging, phase 2 study

(2012) Robert P Giugliano et al.   LANCET

Proteasomal Inhibition Promotes ATP-Binding Cassette Transporter A1 (ABCA1) and ABCG1 Expression and Cholesterol Efflux From Macrophages In Vitro and In Vivo

(2011) Masatsune Ogura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Janus kinase activation by cytokine oncostatin M decreases PCSK9 expression in liver cells

(2011) Aiqin Cao et al.   JOURNAL OF LIPID RESEARCH

Proteasome inhibition during myocardial infarction

(2009) X. Yu et al.   CARDIOVASCULAR RESEARCH

Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for proteasome inhibitor-mediated cardioprotection

(2009) H. Dreger et al.   CARDIOVASCULAR RESEARCH

Hepatocyte Nuclear Factor 1α Plays a Critical Role inPCSK9Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine

(2009) Hai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor

(2009) Noam Zelcer et al.   SCIENCE

Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes

(2008) Cédric Langhi et al.   FEBS LETTERS

Dual Mechanisms for the Fibrate-mediated Repression of Proprotein Convertase Subtilisin/Kexin Type 9

(2008) Sanae Kourimate et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitination as a Priming Process of PKC αand PKC ε Degradation in the αT3-1 Gonadotrope Cell Line

(2008) Benoit Poulin et al.   NEUROENDOCRINOLOGY

ɛPKC confers acute tolerance to cerebral ischemic reperfusion injury

(2008) Rachel Bright et al.   NEUROSCIENCE LETTERS

PCSK9 and LDL cholesterol: unravelling the target to design the bullet

(2008) Philippe Costet et al.   TRENDS IN BIOCHEMICAL SCIENCES

Suppression of Cardiomyocyte Hypertrophy by Inhibition of the Ubiquitin-Proteasome System

(2007) Silke Meiners et al.   HYPERTENSION