Probucol suppresses human glioma cell proliferation in vitro via ROS production and LKB1-AMPK activation

Danthron activates AMP-activated protein kinase and regulates lipid and glucose metabolism in vitro

(2013) Rong Zhou et al.   ACTA PHARMACOLOGICA SINICA

Probucol Increases Striatal Glutathione Peroxidase Activity and Protects against 3-Nitropropionic Acid-Induced Pro-Oxidative Damage in Rats

(2013) Dirleise Colle et al.   PLoS One

Wogonin induces apoptosis by activating the AMPK and p53 signaling pathways in human glioblastoma cells

(2012) Dae-Hee Lee et al.   CELLULAR SIGNALLING

Primary brain tumours in adults

(2012) Damien Ricard et al.   LANCET

Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo

(2012) Shuangxi Wang et al.   NATURE MEDICINE

Metformin attenuates pressure overload-induced cardiac hypertrophy via AMPK activation

(2011) Yong-nan Fu et al.   ACTA PHARMACOLOGICA SINICA

AMPKα2 Deletion Exacerbates Neointima Formation by Upregulating Skp2 in Vascular Smooth Muscle Cells

(2011) Ping Song et al.   CIRCULATION RESEARCH

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

AMPKα2 Deletion Causes Aberrant Expression and Activation of NAD(P)H Oxidase and Consequent Endothelial Dysfunction In Vivo

(2010) Shuangxi Wang et al.   CIRCULATION RESEARCH

MicroRNA-451 Regulates LKB1/AMPK Signaling and Allows Adaptation to Metabolic Stress in Glioma Cells

(2010) Jakub Godlewski et al.   MOLECULAR CELL

Where are we with probucol: A new life for an old drug?

(2009) Shizuya Yamashita et al.   ATHEROSCLEROSIS

S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo

(2009) Yih-Jer Wu et al.   JOURNAL OF VASCULAR SURGERY

LKB1 and AMPK Family Signaling: The Intimate Link Between Cell Polarity and Energy Metabolism

(2009) Marnix Jansen et al.   PHYSIOLOGICAL REVIEWS

Phosphorylation of LKB1 at Serine 428 by Protein Kinase C-ζ Is Required for Metformin-Enhanced Activation of the AMP-Activated Protein Kinase in Endothelial Cells

(2008) Zhonglin Xie et al.   CIRCULATION

Acute Inhibition of Guanosine Triphosphate Cyclohydrolase 1 Uncouples Endothelial Nitric Oxide Synthase and Elevates Blood Pressure

(2008) Shuangxi Wang et al.   HYPERTENSION

Reactive Nitrogen Species Is Required for the Activation of the AMP-activated Protein Kinase by Statinin Vivo

(2008) Hyoung Chul Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-atherosclerotic and anti-diabetic properties of probucol and related compounds

(2008) David Tanous et al.   REDOX REPORT