Betulinic acid inhibits autophagic flux and induces apoptosis in human multiple myeloma cells in vitro

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1

(2011) Rong Zeng et al.   ACTA PHARMACOLOGICA SINICA

The time-dependent autophagy protects against apoptosis with possible involvement of Sirt1 protein in multiple myeloma under nutrient depletion

(2011) Rong Zeng et al.   ANNALS OF HEMATOLOGY

Betulinic acid delivered in liposomes reduces growth of human lung and colon cancers in mice without causing systemic toxicity

(2011) Franziska B. Mullauer et al.   ANTI-CANCER DRUGS

Betulinic acid, a natural compound with potent anticancer effects

(2010) Franziska B. Mullauer et al.   ANTI-CANCER DRUGS

DAMP-mediated autophagy contributes to drug resistance

(2010) Liying Liu et al.   Autophagy

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

The role of autophagy in anticancer therapy: promises and uncertainties

(2010) M. P. Tschan et al.   JOURNAL OF INTERNAL MEDICINE

Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells

(2009) Li-jing Yang et al.   ACTA PHARMACOLOGICA SINICA

Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL

(2009) S Luo et al.   CELL DEATH AND DIFFERENTIATION

Targeting mitochondrial apoptosis by betulinic acid in human cancers

(2009) Simone Fulda et al.   DRUG DISCOVERY TODAY

Emerging therapies for multiple myeloma

(2009) Klaus Podar et al.   EXPERT OPINION ON EMERGING DRUGS

Betulinic acid-mediated inhibitory effect on hepatitis B virus by suppression of manganese superoxide dismutase expression

(2009) Dachun Yao et al.   FEBS Journal

Effect of autophagy on multiple myeloma cell viability

(2009) B. Hoang et al.   MOLECULAR CANCER THERAPEUTICS

Peltophorum Africanum, a Traditional South African Medicinal Plant, Contains an Anti HIV-1 Constituent, Betulinic Acid

(2009) Andros Theo et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE