18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels

Late Sodium Current Contributes to the Reverse Rate-Dependent Effect of I Kr Inhibition on Ventricular Repolarization

(2011) Lin Wu et al.   CIRCULATION

Ion Channel Therapy of Ischemic Heart Disease: From Calcium Channel Blockers to Late Sodium Current Inhibition

(2011) C. Richard Conti   CLINICAL CARDIOLOGY

Ranolazine for the Treatment of Heart Failure With Preserved Ejection Fraction: Background, Aims, and Design of the RALI-DHF Study

(2011) Claudius Jacobshagen et al.   CLINICAL CARDIOLOGY

Electrophysiologic basis for the antiarrhythmic actions of ranolazine

(2011) Charles Antzelevitch et al.   HEART RHYTHM

Suppression of Re-Entrant and Multifocal Ventricular Fibrillation by the Late Sodium Current Blocker Ranolazine

(2011) Norishige Morita et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Blocking effect of methylflavonolamine on human NaV1.5 channels expressed in Xenopus laevis oocytes and on sodium currents in rabbit ventricular myocytes

(2010) Xin-rong Fan et al.   ACTA PHARMACOLOGICA SINICA

Selective inhibition of persistent sodium current by F 15845 prevents ischaemia-induced arrhythmias

(2010) C Pignier et al.   BRITISH JOURNAL OF PHARMACOLOGY

Drug-induced hERG Block and Long QT Syndrome

(2010) Harry J. Witchel   Cardiovascular Therapeutics

Contribution of late sodium current (INa-L) to rate adaptation of ventricular repolarization and reverse use-dependence of QT-prolonging agents

(2010) Donglin Guo et al.   HEART RHYTHM

Molecular determinants of Kv1.5 channel block by diphenyl phosphine oxide-1

(2010) Yi-mei Du et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Sodium Channel Molecular Conformations and Antiarrhythmic Drug Affinity

(2010) Michael F. Sheets et al.   TRENDS IN CARDIOVASCULAR MEDICINE

F 15845 inhibits persistent sodium current in the heart and prevents angina in animal models

(2009) B Vacher et al.   BRITISH JOURNAL OF PHARMACOLOGY

Use-dependent block of cardiac late Na+ current by ranolazine

(2009) Sridharan Rajamani et al.   HEART RHYTHM

Rapid Kinetic Interactions of Ranolazine With HERG K+ Current

(2009) Sridharan Rajamani et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Glycyrretinic acid blocks cardiac sodium channels expressed in Xenopus oocytes

(2009) Yimei Du et al.   JOURNAL OF ETHNOPHARMACOLOGY

Diastolic transient inward current in long QT syndrome type 3 is caused by Ca2+ overload and inhibited by ranolazine

(2009) N. Lindegger et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Electropharmacological properties of telmisartan in blocking hKv1.5 and HERG potassium channels expressed onXenopus laevisoocytes1

(2008) Dan-na TU et al.   ACTA PHARMACOLOGICA SINICA

Ranolazine Shortens Repolarization in Patients with Sustained Inward Sodium Current Due to Type-3 Long-QT Syndrome

(2008) ARTHUR J. MOSS et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Late sodium current inhibition as a new cardioprotective approach

(2008) Sharon L. Hale et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Blockade of gap junction coupling by glycyrrhetinic acids in guinea pig cochlear artery: A whole-cell voltage- and current-clamp study

(2007) B-C Guan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of late sodium current to reduce electrical and mechanical dysfunction of ischaemic myocardium

(2007) J C Shryock et al.   BRITISH JOURNAL OF PHARMACOLOGY