Article
Chemistry, Multidisciplinary
Saptarshi Chakraborty, Rajesh Khamrui, Suhrit Ghosh
Summary: Supramolecular assembly of biomolecules/major molecules aims to simulate complex biological structures and functions, with challenges in protein assembly due to their large molecular weight, structural complexity, and instability. This article presents redox-responsive supramolecular assembly of a protein, forming spherical nanoparticles or fibrous networks in water to enhance the protein's thermal stability.
Article
Chemistry, Multidisciplinary
Anna K. Patterson, Lamisse H. El-Qarra, David K. Smith
Summary: Enantiomers of the low-molecular-weight gelator DBS-CONHNH2, based on d- or l- 1,3 : 2,4-dibenzylidenesorbitol (DBS), were synthesized. Although enantiomeric gels still form when mixtures of enantiomers are used, they are weaker than homochiral gels. The addition of even a small proportion of the opposite enantiomer leads to the loss of nanoscale chirality. Enantiomeric gels encapsulate different enantiomers of the anti-inflammatory drug naproxen, exhibiting thermal and mechanical differences between diastereomeric systems. This study demonstrates the importance of chirality in DBS assembly and its interactions with chiral additives.
CHEMICAL COMMUNICATIONS
(2022)
Article
Engineering, Environmental
Juan Chu, Linqi Cheng, Lan Chen, Heng-guo Wang, Fengchao Cui, Guangshan Zhu
Summary: This study successfully constructed universal organic alkali metal-ion batteries by synthesizing redox-active polymers with multiple redox-active sites and multiple functions. The crystalline and amorphous polymers were systematically studied, and it was found that the amorphous polymer with more active sites and shortened ion diffusion paths exhibited superior performance. The integration of different functional groups in the polymer structure enabled it to have abundant active centers, the ability to absorb ions, and universal electrode-active features at high and low potential.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Yu Liu, Xuemin Chen, Shuhua Yin, Xiaoxi Chang, Chenyan Lv, Jiachen Zang, Xiaojing Leng, Tuo Zhang, Guanghua Zhao
Summary: This study presents a self-assembly approach to fabricating protein origami with a networklike structure by designing dual noncovalent interactions on the different positions of a single protein building block. The approach involves constructing 1D protein filaments through metal coordination and creating network superstructures through cross-linking of the filaments at branch point linkages using pi-pi stacking interactions. The resulting protein networks exhibit reversible, injectable, and self-healing properties and can promote bone regeneration.
Article
Chemistry, Multidisciplinary
Govind P. Maurya, Deepak Verma, Aloka Sinha, Luc Brunsveld, V Haridas
Summary: This study demonstrates the synthesis of simple and tunable hydrophobically driven chiral functional assemblies of diacetylene cored pseudopeptides. The chiral appended amino acid elements and the hydrophobic dialkyne core play important roles in the self-assembly and aggregation induced emission properties of these materials. Moreover, these supramolecular materials show promising applications in inducing chirality into non-chiral liquid crystal matrices.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Polymer Science
Yuntao Tang, Peng Cao, Wangbo Li, Mengting He, Zhifeng Dai, Yubing Xiong
Summary: The study demonstrated that the sizes of PIL microgels could be well-tuned through the feeding ratio of IL monomers to the cross-linker; Fc-anchored PIL microgels were found to be electrochemically active and could respond reversibly to the redox stimulus; An enhanced peak current could be achieved when PIL microgel-supported Fc groups were complexed with 8-CD dimer.
Article
Nanoscience & Nanotechnology
Longfei Yao, Kuo Fu, Guofeng Liu
Summary: This study investigates the effect of solvent on chirality transfer and energy transmission in supramolecular polymer system and identifies the hierarchical assembly behavior regulated by the solvent effect. A designed AIE-core building block shows morphologic transformations with chirality amplification for both CD and CPL measurements. Time-dependent CD test demonstrates the hierarchical assembly of aggregates. The results contribute to the development of supramolecular materials with enhanced CPL performance and dynamic chirality.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Patrick Petschacher, Reza Ghanbari, Carina Sampl, Helmar Wiltsche, Roland Kadar, Stefan Spirk, Tiina Nypelo
Summary: Sulfate groups on cellulose nanocrystals (CNCs) provide colloidal stability, and the introduction of sodium counter cations enables drying of the CNC suspensions without irreversible aggregation. Ion exchange is an efficient method to exchange sulfate half esters with alkali metal cations. K-CNC exhibits different rheological and birefringence properties compared to other alkali metal modifications.
Article
Chemistry, Physical
Nusik Gedikoglu, Pablo Salcedo-Abraira, Long H. B. Nguyen, Nathalie Guillou, Nicolas Dupre, Christophe Payen, Nicolas Louvain, Lorenzo Stievano, Philippe Poizot, Thomas Devic
Summary: Metal organic frameworks (MOFs) built up from metal-sulfur (M-S) bonds have shown impressive electronic properties and good stability. In this study, three new compounds were discovered through the investigation of the reactivity between a mixed thiolate-carboxylate ligand and Fe(III) salts. One of the compounds exhibited potential reversible electrochemical activity and good capacity retention.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Chemistry, Multidisciplinary
Iram F. Mansoor, Kaitlyn G. Dutton, Daniel A. Rothschild, Richard C. Remsing, Mark C. Lipke
Summary: The host-guest chemistry of metal-organic nanocages is driven by thermodynamically favorable interactions, allowing control of guest uptake and release by switching affinity on or off. By reducing the host, rapid uptake of organometallic cations can be achieved, forming metastable cation-in-cation complexes with unprecedented stability. Subsequent reoxidation of the hosts traps the guests, demonstrating a way to confine guests in unfavorable environments.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Boya Sun, Qiongqiong Lu, Kaixuan Chen, Wenhao Zheng, Zhongquan Liao, Nikolaj Lopatik, Dongqi Li, Martin Hantusch, Shengqiang Zhou, Hai Wang, Zdenek Sofer, Eike Brunner, Ehrenfried Zschech, Mischa Bonn, Richard Dronskowski, Daria Mikhailova, Qinglei Liu, Di Zhang, Minghao Yu, Xinliang Feng
Summary: This study reports on the construction of redox-active phosphorus-oxygen terminals as an attractive strategy to significantly enhance the specific capacities of Nb4C3 MXenes for ultrafast Na+ storage. The molecular-level design of MXene terminals provides opportunities for developing high-capacity and fast-charging electrodes, alleviating the energy-power tradeoff typical for energy-storage devices.
ADVANCED MATERIALS
(2022)
Article
Multidisciplinary Sciences
Sean F. Jordan, Ioannis Ioannou, Hanadi Rammu, Aaron Halpern, Lara K. Bogart, Minkoo Ahn, Rafaela Vasiliadou, John Christodoulou, Amandine Marechal, Nick Lane
Summary: Iron-sulfur (FeS) proteins are ancient and fundamental to life, being involved in electron transfer and CO2 fixation. The study demonstrates that FeS clusters can spontaneously form in the presence of the amino acid cysteine under conditions similar to Hadean alkaline hydrothermal vents, suggesting a plausible mechanism for their emergence at the origin of life.
NATURE COMMUNICATIONS
(2021)
Article
Materials Science, Multidisciplinary
Deepak Bansal, Pritam Mukhopadhyay
Summary: A facile one-pot synthetic route for the preparation of asymmetric core-modified naphthalenediimide D-pi-A scaffold(s) is reported, showing multi-state redox properties and strong molecular stacking interactions. Moreover, the synthesized scaffolds can generate panchromatic radical anions, indicating potential applications in open-shell supramolecular networks.
JOURNAL OF MATERIALS CHEMISTRY C
(2021)
Article
Chemistry, Applied
Cedric Przybylski, Veronique Bonnet
Summary: This study investigated the size and shape of supramolecular assemblies between cyclo-oligosaccharides and proton, ammonium or a series of alkali metals using ESI-TIMS. The results were in good agreement with molecular modeling, and TIMS allowed discrimination and estimation of different conformations in cyclodextrins.
CARBOHYDRATE POLYMERS
(2022)
Article
Nanoscience & Nanotechnology
Zhe Yang, Jianjian Zhong, Chaoliang Zheng, Zhicheng Wei, Jiameng Feng, Jianling Li
Summary: This study successfully addresses the issues of voltage hysteresis and capacity attenuation in manganese-based cathode materials by controlling the formation of ordered Li-Mn superstructures. It also reduces the generation of reactive oxygen species and provides effective ideas for designing various superstructures and utilizing anionic redox.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Lara Rouco, Rebeca Alvarino, Amparo Alfonso, Maria J. Romero, Rosa Pedrido, Marcelino Maneiro
Summary: This study investigates the antioxidant properties of four manganese(II) complexes with fluorescent dyes and their protective effects on SH-SY5Y neuroblastoma cells. The complexes showed significant antioxidant activity and improved cell survival by reducing reactive oxygen species release. The incorporation of the fluorescent label allowed the study of their cellular uptake in the neuroblastoma cells.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Sandra Fernandez-Farina, Luis M. Gonzalez-Barcia, Maria J. Romero, Javier Garcia-Tojal, Marcelino Maneiro, Jose M. Seco, Guillermo Zaragoza, Miguel Martinez-Calvo, Ana M. Gonzalez-Noya, Rosa Pedrido
Summary: This study presents the first example of a silver double-tetranuclear cluster helicate obtained from a bisthiosemicarbazone ligand using electrochemical synthesis. The cluster helicate undergoes a rare desulfurization process in chloroform, giving rise to a cationic silver dihelicate, which represents the first silver-mediated desulfurization reaction.
INORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Inorganic & Nuclear
Sandra Fernandez-Farina, Miguel Martinez-Calvo, Marcelino Maneiro, Jose M. Seco, Guillermo Zaragoza, Ana M. Gonzalez-Noya, Rosa Pedrido
Summary: We report two different approaches to isolate neutral and cationic mesocate-type metallosupramolecular architectures derived from coinage monovalent ions. By using a thiocarbohydrazone ligand, we successfully prepared a series of neutral and cationic dinuclear mesocates and analyzed their crystal structures, revealing the influence of synthetic methodology and counterions on the mesocates' structures.
INORGANIC CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Rocio Uzal-Varela, Veronique Patinec, Raphael Tripier, Laura Valencia, Marcelino Maneiro, Moises Canle, Carlos Platas-Iglesias, David Esteban-Gomez, Emilia Iglesias
Summary: Several bifunctional chelators have been synthesized in recent years for the development of new (64)Cu-based PET agents. High stability and kinetic inertness are important when designing metal-based PET probes. Different competitive assays are commonly used to evaluate the dissociation mechanisms of Cu(II) in the body. This study fills the gap by providing a detailed spectroscopic study of the kinetic behavior of different macrocyclic Cu(II) complexes.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Sandra Fernandez-Farina, Isabel Velo-Heleno, Rocio Carballido, Miguel Martinez-Calvo, Ramiro Barcia, Oscar Palacios, Merce Capdevila, Ana M. Gonzalez-Noya, Rosa Pedrido
Summary: This article reports on the design of three zinc helicates derived from bisthiosemicarbazone ligands with different terminal groups. The helicates were obtained using an electrochemical methodology and fully characterized using various techniques, including X-ray diffraction. Biological studies were conducted to assess the toxicity and interaction of these helicates with proteins and oligonucleotides, showing low toxicity and no covalent interaction. In vitro cytotoxicity tests were performed on various cancer cell lines, comparing the IC50 values with cisplatin, to evaluate the antitumor activity of the zinc helicates.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Sandra Fernandez-Farina, Isabel Velo-Heleno, Miguel Martinez-Calvo, Marcelino Maneiro, Rosa Pedrido, Ana M. Gonzalez-Noya
Summary: In this study, two new neutral copper(II) helicates, [Cu-2(L-1)(2)].4CH(3)CN and [Cu-2(L-2)(2)].CH3CN, were synthesized using an electrochemical method. The ligand design and the resulting metallosupramolecular structure were investigated. The magnetic properties of the copper(II) helicates were characterized using EPR spectroscopy and DC magnetic susceptibility measurements.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Ruben Gil-Garcia, Gotzon Madariaga, Alondra Jimenez-Perez, Ignacio Herran-Torres, Adrian Gago-Gonzalez, Maria Ugalde, Vaidas Januskaitis, Joaquin Barrera-Garcia, Maite Insausti, Maria S. Galletero, Joaquin Borras, Jose Vicente Cuevas, Rosa Pedrido, Patricia Gomez-Saiz, Luis Lezama, Javier Garcia-Tojal
Summary: The use of perchlorate ancillary ligands demonstrates the structural diversity of thiosemicarbazone copper(II) systems. Different types of compounds, including multi-nuclear species and mononuclear entities, were studied. Experimental evidence and theoretical calculations support a proposed mechanism for the partial desulfurization of TSC-Cu(II) entities.
Article
Chemistry, Inorganic & Nuclear
Sandra Fernandez-Farina, Miguel Martinez-Calvo, Maria J. Romero, Jose M. Seco, Guillermo Zaragoza, Rosa Pedrido, Ana M. Gonzalez-Noya
Summary: The mechanism of carbamate activation promoted by different metal ions has been investigated, revealing that the reaction between carbamate ligand H2L and chloride metal salts leads to hydrolysis and release of products.
DALTON TRANSACTIONS
(2022)