Journal
ACTA PHARMACEUTICA
Volume 61, Issue 2, Pages 187-201Publisher
HRVATSKO FARMACEUTSKO DRUSTOV (HFD)-CROATION PHARMACEUTICAL SOC
DOI: 10.2478/v10007-011-0018-2
Keywords
imidazole; reverse transcriptase; non-nucleoside reverse transcriptase; anti-HIV; antibacterial
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Funding
- UGC, New Delhi, India
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A series of 1-(2-methyl-4-nitro-imidazol-1-yl)-3-arylaminopropan-2-ones (2a-e), 2-methyl-5-nitro-1-{2-[ arylmethoxy] ethyl}-1H-imidazoles (5a-d), and N-(3-hydroxy-phenyl)-2-(substituted imidazol-1-yl) alkanamides (8a-e) were synthesized with the aim to develop novel imidazole analogs with broad-spectrum chemotherapeutic properties. Title compounds were evaluated for their anti-HIV and antibacterial activities.
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