Article
Biochemistry & Molecular Biology
Laura Rizzi, Marco Turati, Elena Bresciani, Filippo Maria Anghilieri, Ramona Meanti, Laura Molteni, Massimiliano Piatti, Nicolo Zanchi, Silvia Coco, Francesco Buonanotte, Luca Rigamonti, Giovanni Zatti, Vittorio Locatelli, Robert J. J. Omeljaniuk, Marco Bigoni, Antonio Torsello
Summary: This study investigated the changes in microRNA expression profiles in knee synovial fluid of patients with osteoarthritis (OA) and anterior cruciate ligament (ACL) rupture. The results showed that specific microRNAs were expressed differently in OA and ACL tear samples. These findings may contribute to further research on the mechanisms and treatments of osteoarthritis and ACL rupture.
Article
Medicine, General & Internal
Zhong Chen, Yuheng Li, Yichi Zhang, Zhengzheng Zhang, Jingsong Wang, Xinghao Deng, Chengxiao Liu, Na Chen, Chuan Jiang, Weiping Li, Bin Song
Summary: This study found that visual function defect, especially low visual fusion range, is a risk factor for knee anterior cruciate ligament (ACL) sports injury. Quick turn, sudden stop, and jump during sports activities are also major risk factors.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Orthopedics
Ryotaro Kumahara, Yuka Kimura, Shizuka Sasaki, Eiji Sasaki, Shugo Maeda, Harehiko Tsukada, Yuji Yamamoto, Eiichi Tsuda, Yasuyuki Ishibashi
Summary: This study aimed to determine the prevalence of Segond fractures and compare knee stability in patients undergoing ACL reconstruction. The results showed that Segond fractures did not affect knee stability evaluations, suggesting that treatment may not be necessary.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Cell & Tissue Engineering
L. Shu, N. Abe, S. Li, N. Sugita
Summary: This study aimed to investigate the effects of posterior tibial slope (PTS) angles on joint kinematics and contact mechanics of intact and anterior cruciate ligament-deficient (ACLD) knees. The results showed that increasing PTS angles significantly affected the tensile force on the ACL in the intact knee and led to differences in kinematics and increased loading on the medial meniscus.
BONE & JOINT RESEARCH
(2022)
Article
Chemistry, Analytical
Mazhar Javed Awan, Mohd Shafry Mohd Rahim, Naomie Salim, Amjad Rehman, Begonya Garcia-Zapirain
Summary: This study applies deep learning to automatically segment ACL tears from MRI images. By using the U-Net architecture and semantic segmentation technique, high accuracy segmentation results have been achieved. The method shows promising potential in the field of medical image analysis.
Article
Orthopedics
Marilia Novaes, Adriana Carvalho, Juliana F. Sauer, Guilherme C. Brech, Camilo P. Helito, Silvia M. A. Joao
Summary: Patients with a clinical indication for ACL + ALL combined reconstruction surgery showed increased COP displacement compared to patients with indication for an ACL isolated reconstruction surgery.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Orthopedics
Heng Gong, Qingshan Li, Yu Len, Ke He, Wenbo Zhao, Yu Li, Guanjun Sun, Xu Peng, Yi Yin
Summary: This study aimed to clarify the clinical value of the posterior cruciate ligament index (PCLI) in anterior cruciate ligament (ACL) rupture, explore its relationship with the course of disease, and identify its influencing factors. The results showed that the PCLI decreased with time, especially in the chronic phase, and was not related to the depth of the lateral femoral notch sign or injuries of other structures in the knee joint. It can be used as a reliable indirect sign of ACL rupture.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Orthopedics
Simon Lukas, Sophie Putman, Cyril Delay, Alexandre Blairon, Emmanuel Chazard, Romain Letartre
Summary: There is a lack of simple tools for emergency and primary-care physicians to decide whether to refer patients with knee ligament sprains to specialists. This study developed and validated a clinical score that can help identify patients at high risk of ACL tears, providing guidance for clinical decision-making.
ORTHOPAEDICS & TRAUMATOLOGY-SURGERY & RESEARCH
(2022)
Review
Orthopedics
Eoghan T. Hurley, Jordan W. Fried, Matthew T. Kingery, Eric J. Strauss, Michael J. Alaia
Summary: The current evidence supports the notion that concomitant ALL reconstruction alongside soft tissue graft ACL reconstruction can improve clinical outcomes by enhancing knee stability and reducing re-rupture rates.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2021)
Article
Engineering, Biomedical
Huijuan Shi, Li Ding, Shuang Ren, Yanfang Jiang, Haocheng Zhang, Xiaoqing Hu, Hongshi Huang, Yingfang Ao
Summary: Biomechanical risk factors associated with ACL injury are still inconclusive. Bone bruises identified post-ACL injury on MRI may represent the impact footprint, indicating changes in knee kinematics during injury.
ANNALS OF BIOMEDICAL ENGINEERING
(2021)
Article
Sport Sciences
Roula Kotsifaki, Vasileios Korakakis, Enda King, Olivia Barbosa, Dustin Maree, Michail Pantouveris, Andreas Bjerregaard, Julius Luomajoki, Jan Wilhelmsen, Rodney Whiteley
Summary: This guideline provides clinical practice recommendations for rehabilitation after ACL reconstruction, based on AGREE II and GRADE approach. It evaluates the effectiveness of rehabilitation interventions through randomized clinical trials and systematic reviews, and guides clinicians and patients on the optimal rehabilitation protocol. Exercise interventions are the main focus of rehabilitation, but there is limited evidence on the relationship between exercise volume/intensity and outcomes.
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Article
Orthopedics
Kyoung-Tak Kang, Yong-Gon Koh, Kyoung-Mi Park, Chong-Hyuk Choi, Min Jung, Hyunik Cho, Sung-Hwan Kim
Summary: This study investigated the association between the anterolateral ligament (ALL) and anterior cruciate ligament (ACL) under dynamic loading conditions using computer simulation. The results showed that ACL deficiency significantly increased the force exerted on the ALL, and vice versa. Additionally, deficiencies in ACL and ALL increased the contact forces on the tibiofemoral (TF) and patellofemoral (PF) joints.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2022)
Article
Orthopedics
Alexei Yumashev, Tatyana Baltina, Dmitrii Babaskin
Summary: The study assessed the survival rates of grafts in ACL revision surgery, with the BTB group showing better results at 1 and 5 years postoperatively compared to the ST/G group. Graft survival after revision was lower than after the primary operation, with no statistically significant differences between ST/G and BTB autografts.
Letter
Engineering, Biomedical
Alberto Grassi, Piero Agostinone, Stefano Di Paolo, Stefano Zaffagnini
Summary: The study provided an interesting and strong paper, but caution should be used when drawing conclusions about the mechanism of Anterior Cruciate Ligament injury from the data interpretation.
ANNALS OF BIOMEDICAL ENGINEERING
(2021)
Article
Orthopedics
Janina Kaarre, Balint Zsidai, Philipp W. Winkler, Eric Narup, Alexandra Horvath, Eleonor Svantesson, Eric Hamrin Senorski, Volker Musahl, Kristian Samuelsson
Summary: This study compares patient characteristics and injury profiles in patients with anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) injuries. The study found that ACL and PCL groups have distinct injury patterns related to BMI, age, sex, and activities.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)