Article
Medicine, General & Internal
Yueh-Ling Chen, Christy Pu, Ken-Kuo Lin, Jiahn-Shing Lee, Laura Liu, Chiun-Ho Hou
Summary: The purpose of this study was to analyze the visual quality and contrast sensitivity in patients after intraocular lens implantation with sutured scleral fixation. The study found that ocular higher-order aberrations and refractive errors were higher in the scleral-fixation group compared to the in-bag group, but there was no significant difference in contrast sensitivity between the two groups.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
C. Talens-Estarelles, A. M. Garcia-Del Valle, S. Garcia-Lazaro
Summary: The study found that simultaneous-image multifocal contact lenses with central optical zone diameters of 80-90% and 90-100% of photopic pupil diameter provided better distance and intermediate visual acuity, without affecting near performance, and superior contrast sensitivity at medium and high spatial frequencies compared to lower central optical zone diameter designs.
CONTACT LENS & ANTERIOR EYE
(2022)
Article
Medicine, General & Internal
Miguel A. Gil, Consuelo Varon, Genis Cardona, Jose A. Buil
Summary: This study compared the contrast sensitivity and quality of vision among different types of presbyopia correcting intraocular lenses (IOLs) and found that monofocal lenses performed better in contrast sensitivity and photic phenomena. The Symfony ZXR00, which has an extended depth of focus, showed superior contrast sensitivity compared to other multifocal IOL designs.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Yong Woo Lee, Chul Young Choi, Kun Moon, Yong Jin Jeong, Sang Il An, Je Myung Lee, Jong Ho Lee, Min Cheol Seong
Summary: This study compares the optical quality, contrast sensitivity, and subjective photic phenomena of new hydrophobic diffractive multifocal intraocular lenses (IOL) with an existing multifocal IOL. The results show that the new IOL provides better contrast sensitivity and lower subjective photic phenomena.
Article
Medicine, General & Internal
Yuan Ning, Yushuang Shao, Jiangyue Zhao, Jinsong Zhang, Mingwu Wang, Yu Qin
Summary: This study evaluated the stability of four different types of aspheric intraocular lenses (IOLs) and found that one-piece multi-point fixed acrylic IOLs demonstrate better stability compared to three-piece two-point fixed silicone IOLs. The IOL decentration, tilt, and coma increase gradually over time, with a positive linear correlation observed between IOL decentration or tilt and coma one year postoperatively. Ocular coma-like aberrations are influenced by the stability of IOLs.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2021)
Article
Ophthalmology
Seth M. Pantanelli, Tara O'Rourke, Olga Bolognia, Kathleen Scruggs, Amy Longenecker, Erik Lehman
Summary: This study compared outcomes in cataract surgery patients who received different intraocular lenses (IOLs). The results showed that the nondiffractive extended depth-of-focus (ND-EDOF) and neutral aspheric monofocal IOLs had similar performance in distance vision. However, ND-EDOF patients had better intermediate and near vision, and a higher proportion of them reported not needing glasses. The severity of photic phenomena was low in both groups.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2023)
Review
Medicine, General & Internal
Diego Zamora-de La Cruz, John Bartlett, Mario Gutierrez, Sueko M. Ng
Summary: Presbyopia is a common eye condition that affects the ability to focus on close objects. Trifocal and bifocal intraocular lenses are used in cataract surgery to restore vision in individuals with presbyopia. This study compared the effectiveness and safety of trifocal and bifocal lenses and found that trifocal lenses may improve intermediate visual acuity compared to bifocal lenses, but there was no difference in distance visual acuity and near visual acuity between the two types of lenses.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2023)
Article
Ophthalmology
Joaquin Fernandez, Javier Garcia-Montesinos, Javier Martinez, David P. Pinero, Manuel Rodriguez-Vallejo
Summary: This study assessed the degree of PCO and its impact on CSDC after implantation of two trifocal IOLs, revealing that PCO can decrease CSDC in patients. Despite using the same hydrophilic material, differences were observed in PCO grading and Nd:YAG capsulotomy rate between the two IOLs, with higher rates in AT compared to L.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2021)
Article
Multidisciplinary Sciences
Adiba Ali, Maitreyee Roy, Hind Saeed Alzahrani, Sieu K. Khuu
Summary: The study found that the perceived speed of both chromatic and achromatic test stimuli was reduced by 6 to 20% when viewed through blue-light filtering lenses. Lenses that attenuated the most blue-light produced the largest reductions in perceived speed.
SCIENTIFIC REPORTS
(2021)
Article
Ophthalmology
Sheetal Brar, Hemanth Reddy Vanga, Mamta Lakhana Shah, Sri Ganesh
Summary: This study compared the clinical outcomes of Optiflex Genesis, Eyecryl Plus (ASHFY 600), and Tecnis-1 intraocular lenses. The results showed that all three lenses had similar results in terms of visual and refractive parameters, postoperative aberrations, contrast sensitivity, and posterior capsule opacification.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Joaquin Fernandez, Noemi Burguera, Carlos Rocha-de-Lossada, Rahul Rachwani-Anil, Manuel Rodriguez-Vallejo
Summary: The study aims to determine cut-off points for age and cataract grading objective systems to predict the restoration of contrast sensitivity (CS) after multifocal intraocular lens (MIOL) implantation. The results showed that both age and objective metrics were correlated with CS, and the cut-off points provided consistency in predicting the loss of CDVA and unexpected near vision loss.
INTERNATIONAL OPHTHALMOLOGY
(2023)
Article
Medicine, General & Internal
Ivajlo Popov, Denisa Jurenova, Jela Valaskova, Diego Sanchez-Chicharro, Jana Stefanickova, Iveta Waczulikova, Vladimir Krasnik
Summary: This study compared the visual outcomes between eyes implanted with blue-light-filtering intraocular lenses and eyes implanted with UV-light-filtering intraocular lenses. The results showed no significant differences in any of the tested parameters between the two groups, with only a slight shift in color vision observed.
MEDICINA-LITHUANIA
(2021)
Article
Health Care Sciences & Services
Lian Duan, Guangfu Dang, Jinling Ge, Yang Gao, Lihua Wang
Summary: This study evaluated the visual function of Chinese cataract patients six months after cataract surgery with two different guiding ideologies. The results showed that individual implantation of aspheric IOLs based on preoperative corneal spherical aberration could improve patients' contrast sensitivity at 2.5 degrees, but there was no significant difference in BCVA, contrast sensitivity at other special frequency, and subjective visual function. Therefore, individualized implantation of aspheric IOLs is effective.
TECHNOLOGY AND HEALTH CARE
(2023)
Article
Ophthalmology
Toshihiro Sakisaka, Keiichiro Minami, Keita Takada, Yosai Mori, Kazunori Miyata
Summary: This prospective study compared the visual function of eyes with diffractive EDOF intraocular lenses (IOLs) and monofocal IOLs. The results showed that EDOF IOLs provided better visual acuity at closer distances, with no significant differences in contrast sensitivities and dynamic visual function.
Article
Ophthalmology
Jose Salgado-Borges, Anabela Borges, Isabel Ferreira, Jose Manuel Gonzalez-Meijome, Miguel Faria-Ribeiro
Summary: This study compared the refractive power profile, subjective depth-of-field, and objective optical quality of two advanced monofocal intraocular lenses. The results showed that both lenses had similar refractive power profiles and objective optical quality, but there was a slight difference in subjective performance.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Sonia Razafimino, Elias Flockerzi, Elena Zemova, Christian Munteanu, Berthold Seitz
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
(2023)
Editorial Material
Ophthalmology
Doris Fraenkel, Loic Hamon, Isabel Weinstein, Berthold Seitz, Loay Daas
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
(2023)
Article
Ophthalmology
Tim Berger, Berthold Seitz, Loic Hamon, Fidelis Flockerzi, Ursula Schlotzer-Schrehardt, Loay Daas
Summary: This study used light and transmission electron microscopy to examine corneal buttons after DALK surgery. The findings revealed irregularities in collagen distribution and degeneration of keratocytes in the interface area, suggesting that the choice of surgical method can affect the postoperative visual outcome.
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
(2023)
Article
Ophthalmology
Tim Berger, Berthold Seitz, Fidelis Flockerzi, Loay Daas
Summary: This study emphasizes the importance of using a sufficiently large corneal graft in primary penetrating keratoplasty to prevent recurrence of fungal keratitis. A clinical case of therapy-resistant fungal keratitis is analyzed, revealing that a larger graft size can effectively prevent recurrence. Therefore, in penetrating keratoplasty, optimal planning and preparation should be made to ensure an adequate safety distance and comprehensive treatment measures.
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
(2023)
Article
Ophthalmology
Haris Sideroudi, Elias Flockerzi, Berthold Seitz
Summary: Differentiating keratoconus from other corneal ectatic diseases is crucial for appropriate management. Various imaging techniques including corneal topography, Scheimpflug cameras, air pulse tonometer, α confocal microscopy, and AS-OCT can assist in diagnosis and differentiation.
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
(2023)
Article
Ophthalmology
Haris Sideroudi, Elias Flockerzi, Theresia Jullien, Loic Hamon, Berthold Seitz
Summary: The study investigated the risk factors for keratoconus progression in different age groups. The factors associated with progression were corneal radius, eye rubbing, corneal thinning, contact lens use, and corneal thickness. Further analysis revealed that anterior chamber volume and keratoconus match index were associated with progression in children, while other factors like distance from apex to the thinnest point and Vogt striae were associated with progression in young and middle-aged adults.
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
(2023)
Article
Ophthalmology
Kassandra Xanthopoulou, Georgia Milioti, Loay Daas, Cristian Munteanu, Berthold Seitz, Elias Flockerzi
Summary: The efficacy of accelerated epithelium-off corneal crosslinking was evaluated in keratoconus patients < 18 years of age. The study showed that this treatment can stabilize KC progression even > 2 years postoperatively and leads to a deep demarcation line.
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
(2023)
Article
Medicine, General & Internal
Emilia Sophie Stuhlmacher, Shady Suffo, Cristian Munteanu, Berthold Seitz, Loay Daas
Summary: This study evaluated the learning curve of individual surgeons for DMEK and Triple-DMEK surgeries and assessed the impact of experience on outcomes. The results showed a significant decrease in surgery duration, graft preparation time, and the re-bubbling rate with increased experience. However, there were no significant changes in visual acuity and central corneal thickness. Different surgeons also exhibited significant differences in surgery duration and graft preparation time.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Ophthalmology
Tim Berger, Nora Szentmary, Ning Chai, Elias Flockerzi, Loay Daas, Tanja Stachon, Berthold Seitz
Summary: The purpose of this research is to investigate the expression of cytokines and ROS-related genes in stromal cells of healthy and keratoconus (KC) corneas. Expression analysis was performed for cytokines and ROS-related genes in corneal fibroblasts (HCFs/KC-HCFs) or keratocytes (Keratocytes/KC-Keratocytes) using qPCR and ELISA. The study found that the expression of most inflammatory markers was decreased in keratocytes compared to fibroblasts, and there were no differences in cytokine expression between healthy and keratoconus cells. TNF-alpha expression was increased in KC keratocytes compared to corneal fibroblasts. No differential expression of ROS-related genes was detected between healthy and diseased cells in both fibroblasts and keratocytes.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2023)
Article
Oncology
Theodora Tsimpaki, Nikolaos E. Bechrakis, Berthold Seitz, Miriam M. Kraemer, Hongtao Liu, Sami Dalbah, Ekaterina Sokolenko, Utta Berchner-Pfannschmidt, Miltiadis Fiorentzis
Summary: The study aimed to establish a new in vivo patient-derived xenograft (PDX) model for uveal melanoma (UM) based on the chick chorioallantoic membrane (CAM) assay. Various techniques and tools were investigated for the assessment of growth, vascularity, and viability of the implanted grafts. The CAM-based PDX model has potential for novel diagnostic and therapeutic experimentation in the field of ocular melanoma.
Article
Ophthalmology
Elias Flockerzi, Christina Turner, Berthold Seitz, Geker Study Grp Collaborators, Geker Study Grp
Summary: This retrospective multicentric panel study investigated the number, types, and indications for corneal transplantation in Germany from 2011 to 2021 and compared them internationally. The study found that the reported number of keratoplasties more than doubled during this period. DMEK has become the predominant procedure since 2016, while PKP showed a slight decrease over the decade. Rating: 9/10.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Medicine, General & Internal
Alaa Din Abdin, Machteld Devenijn, Roxana Fulga, Achim Langenbucher, Berthold Seitz, Hakan Kaymak
Summary: This study aimed to investigate the prevalence of geographic atrophy (GA) in advanced age-related macular degeneration (AMD) and the proportion of eyes eligible for treatment with intravitreal pegcetacoplan. A retrospective cross-sectional study was conducted, including all AMD patients who visited a specific center in 2021. It was found that at least a quarter of eyes with advanced AMD would meet the indication criteria for treatment with pegcetacoplan, and neovascular AMD was associated with a higher likelihood of foveal involvement in GA compared to dry AMD.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Caroline Chan, Berthold Seitz, Barbara Kaesmann-Kellner
Summary: This study investigated a large sample of achromatopsia patients and found that the disease is predominantly stable. The most commonly used visual aids are edge filter glasses and enlarged reading glasses.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Ophthalmology
Burak Mergen, Tim Berger, Loic Hamon, Loay Daas, Berthold Seitz
Summary: This case report demonstrates that quadruple DMEK may be a feasible approach for managing chronic endothelial cell decompensation secondary to iris-claw ACIOL implantation.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Hakan Kaymak, Kai Neller, Birte Graff, Achim Langenbucher, Berthold Seitz, Hartmut Schwahn, Karsten Klabe
Summary: Patients with mild and moderate macular disorders, such as AMD and ERM, show an induced contrast adaptation, i.e. a gain in contrast sensitivity, which is not different from healthy subjects.
CURRENT EYE RESEARCH
(2023)
