Journal
ACTA OPHTHALMOLOGICA
Volume 88, Issue 6, Pages 622-629Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1755-3768.2009.01621.x
Keywords
choroid; circulatory physiopathology; flux of red blood cells; iris; laser Doppler flowmetry; ocular blood flow; retina
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Funding
- Fondazione Cassa di Risparmio in Bologna
- NATIONAL EYE INSTITUTE [R43EY018772] Funding Source: NIH RePORTER
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This article describes the technique of continuous laser Doppler flowmetry (LDF) as applied to the measurement of the flux of red blood cells in the optic nerve head, iris and subfoveal choroid. Starting with the exposition of the physical principles underlying LDF, we first describe the various devices developed to perform LDF in these vascular beds. We then discuss the clinical protocols, blood flow parameters, calibration procedures, reproducibility and limitations of the LDF technique. Various problems still need to be solved in order to bring to light the full potential of LDF in the assessment of microcirculatory haemodynamics.
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