Journal
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
Volume 94, Issue 2, Pages 220-223Publisher
WILEY-BLACKWELL
DOI: 10.1111/aogs.12549
Keywords
Endometrial sarcoma; leiomyoma; leiomyomatosis peritonealis disseminata; leiomyosarcoma; malignant transformation
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Leiomyomatosis peritonealis disseminata is a very rare, benign entity of unknown pathogenesis, characterized by the presence of multiple subperitoneal or peritoneal smooth muscle nodules throughout the peritoneal surface. Mostly the course is asymptomatic and it is found incidentally during laparotomy, laparoscopy or cesarean section. Non-specific symptoms such as abdominal pain, vaginal bleeding, abdominal mass or gastrointestinal signs are described. Rare cases of malignant transformation have been reported. We present a case of disseminated peritoneal leiomyomatosis with an unusual course and transformation to endometrial sarcoma in a 26-year-old previously healthy woman, where the appearance of peritoneal nodules was preceded by multiple incidents of fast fibroid growth and delivery of myomatous growth into the cervical canal.
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