Mild cognitive impairment: pathology and mechanisms

Changes in Parahippocampal White Matter Integrity in Amnestic Mild Cognitive Impairment: A Diffusion Tensor Imaging Study

(2014) E. J. Rogalski et al.   BEHAVIOURAL NEUROLOGY

Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer’s disease

(2011) Pamela E. Potter et al.   ACTA NEUROPATHOLOGICA

Alzheimer’s pathogenesis: is there neuron-to-neuron propagation?

(2011) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Revised criteria for diagnosis of Alzheimer’s disease: National Institute on Aging-Alzheimer's Association diagnostic guidelines for Alzheimer's disease

(2011) Zaven S. Khachaturian   Alzheimers & Dementia

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Longitudinal Patterns of β-Amyloid Deposition in Nondemented Older Adults

(2011) Jitka Sojkova et al.   ARCHIVES OF NEUROLOGY

Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease

(2011) M. D. Ikonomovic et al.   NEUROLOGY

Heterogeneous neuropathological findings in Parkinson’s disease with mild cognitive impairment

(2010) Charles H. Adler et al.   ACTA NEUROPATHOLOGICA

Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression

(2010) Stephen D. Ginsberg et al.   BIOLOGICAL PSYCHIATRY

Baseline Predictors of Clinical Progression among Patients with Dysexecutive Mild Cognitive Impairment

(2010) Julene K. Johnson et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Decreased cerebral α4β2* nicotinic acetylcholine receptor availability in patients with mild cognitive impairment and Alzheimer’s disease assessed with positron emission tomography

(2010) Kai Kendziorra et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Progressive accumulation of amyloid-β oligomers in Alzheimer’s disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins

(2010) Emiley Pham et al.   FEBS Journal

Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease

(2010) Cassia R. Overk et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Revising the definition of Alzheimer's disease: a new lexicon

(2010) Bruno Dubois et al.   LANCET NEUROLOGY

Mechanisms of AD neurodegeneration may be independent of Aβ and its derivatives

(2010) Nikolaos K. Robakis   NEUROBIOLOGY OF AGING

Oxidative stress in Alzheimer disease: A possibility for prevention

(2010) David J. Bonda et al.   NEUROPHARMACOLOGY

Amyloid load in nondemented brains correlates with APOE e4

(2010) Richard J. Caselli et al.   NEUROSCIENCE LETTERS

Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease

(2010) Elliott J. Mufson et al.   NEUROSCIENCE LETTERS

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age

(2009) Eloise Kok et al.   ANNALS OF NEUROLOGY

The neuropathology of probable Alzheimer disease and mild cognitive impairment

(2009) Julie A. Schneider et al.   ANNALS OF NEUROLOGY

APOEpredicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

(2009) John C. Morris et al.   ANNALS OF NEUROLOGY

Cortical α7 Nicotinic Acetylcholine Receptor and β-Amyloid Levels in Early Alzheimer Disease

(2009) Milos D. Ikonomovic et al.   ARCHIVES OF NEUROLOGY

Association of SORL1 gene variants with Alzheimer's disease

(2009) Heike Kölsch et al.   BRAIN RESEARCH

Increased Matrix Metalloproteinase 9 Activity in Mild Cognitive Impairment

(2009) Martin A. Bruno et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease

(2009) S. Peng et al.   JOURNAL OF NEUROSCIENCE

Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

(2009) H. M. Abdul et al.   JOURNAL OF NEUROSCIENCE

123I-5-IA-85380 SPECT Imaging of Nicotinic Receptors in Alzheimer Disease and Mild Cognitive Impairment

(2009) E. M. Mitsis et al.   JOURNAL OF NUCLEAR MEDICINE

Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease

(2009) Joseph L. Price et al.   NEUROBIOLOGY OF AGING

Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease

(2009) A. Drzezga et al.   NEUROLOGY

The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?

(2009) L. T. Grinberg et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Longitudinal Modeling of Age-Related Memory Decline and theAPOEε4 Effect

(2009) Richard J. Caselli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fibrillar amyloid-  burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

(2009) E. M. Reiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly

(2008) Howard Jay Aizenstein et al.   ARCHIVES OF NEUROLOGY

Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications

(2008) Elliott J Mufson et al.   Expert Review of Neurotherapeutics

SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population

(2008) Karolien Bettens et al.   HUMAN MUTATION

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

(2008) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

(2008) Clive Holmes et al.   LANCET

Rate of entorhinal and hippocampal atrophy in incipient and mild AD: Relation to memory function

(2008) T.R. Stoub et al.   NEUROBIOLOGY OF AGING

5-123I-A-85380 binding to the α4β2-nicotinic receptor in mild cognitive impairment

(2008) Emma Terrière et al.   NEUROBIOLOGY OF AGING

Relationship between nicotinic receptors and cognitive function in early Alzheimer’s disease: A 2-[18F]fluoro-A-85380 PET study

(2008) J.R. Ellis et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

No association of dynamin binding protein (DNMBP) gene SNPs and Alzheimer's disease

(2007) Ryan L. Minster et al.   NEUROBIOLOGY OF AGING

MRI of hippocampus and entorhinal cortex in mild cognitive impairment: A follow-up study

(2006) Tero Tapiola et al.   NEUROBIOLOGY OF AGING