Article
Engineering, Biomedical
Daniel Perez-Marcos, Roberta Ronchi, Arthur Giroux, Fanny Brenet, Andrea Serino, Tej Tadi, Olaf Blanke
Summary: This paper presents two tasks in immersive virtual reality to assess unilateral spatial neglect (USN) and proposes new objective scores based on participant's performance. It validates the feasibility of these assessments and suggests that they can help distinguish neurological patients with and without USN.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2023)
Article
Neurosciences
Joon-Ho Shin, Mingyu Kim, Ji-Yeong Lee, Mi-Young Kim, Yu-Jin Jeon, Kwanguk Kim
Summary: In this study, a virtual reality-visual exploration therapy combining elements from the FOPR test and visual exploration therapy (VET) was developed for HSN rehabilitation following stroke. The VR-VET significantly improved clinical assessments and FOPR test results compared to waiting without VR-VET, with more pronounced improvements in the left hemispace.
FRONTIERS IN NEUROSCIENCE
(2023)
Review
Behavioral Sciences
Adriana Salatino, Claudio Zavattaro, Roberto Gammeri, Emanuele Cirillo, Maria Luisa Piatti, Maria Pyasik, Hilary Serra, Lorenzo Pia, Giuliano Geminiani, Raffaella Ricci
Summary: In recent decades, new virtual reality (VR)-based protocols have been proposed for the rehabilitation of Unilateral Spatial Neglect (USN). However, the optimal type of VR protocol and level of immersion remain unclear. In this systematic review, 26 studies were identified and improvements were found in 84.6% of the reviewed studies. Further randomized control trials are needed to validate the clinical efficacy of VR protocols for USN rehabilitation.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Review
Computer Science, Interdisciplinary Applications
S. Cavedoni, P. Cipresso, V. Mancuso, F. Bruni, E. Pedroli
Summary: Virtual reality devices have the potential to be used in the assessment and rehabilitation of USN, but current studies lack methodological rigor and proper evaluation of VR usability, requiring improvement in ecological validity.
Article
Computer Science, Interdisciplinary Applications
Christy Hogan, Petrea Cornwell, Jennifer Fleming, David W. K. Man, David H. K. Shum
Summary: Prospective Memory (PM) is the ability to remember to do something in the future. This study compares different PM measurement tools and confirms the existence of PM impairment after stroke. The Virtual Reality Prospective Memory Shopping Task (VRPMST) shows good sensitivity and ecological validity in measuring PM.
Article
Chemistry, Multidisciplinary
Joris Heyse, Stephanie Carlier, Ewoud Verhelst, Catharine Vander Linden, Femke De Backere, Filip De Turck
Summary: Unilateral Spatial Neglect (USN) is a syndrome that affects multiple modalities and results in the failure to respond to stimuli on the contralesional side of space. Musical Neglect Therapy (MNT), which asks patients to make music, successfully incorporates multiple modalities. This study aims to translate MNT into a VR therapy tool and evaluates its effectiveness through a pilot study.
APPLIED SCIENCES-BASEL
(2022)
Article
Psychology, Multidisciplinary
Bastian I. Hougaard, Hendrik Knoche, Jim Jensen, Lars Evald
Summary: The study showed that using VR in combination with eye tracking measures can be used for individual differential neglect subtype diagnostics, which may be more sensitive than traditional assessment methods.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Neurosciences
Alex Martino Cinnera, Alessio Bisirri, Ilaria Chioccia, Enza Leone, Irene Ciancarelli, Marco Iosa, Giovanni Morone, Valeria Verna
Summary: This review explores the use of Immersive Virtual Reality (IVR) in the treatment of visual perception in Unilateral Spatial Neglect (USN) after a stroke. The findings suggest the potential benefits of IVR in improving visual perception outcomes and motivating patients during rehabilitation.
Review
Psychology, Multidisciplinary
Alexander Pilgaard Kaiser, Kristian Westergaard Villadsen, Afshin Samani, Hendrik Knoche, Lars Evald
Summary: The combination of immersive virtual reality (VR) systems and eye-tracking (ET) holds great potential for the assessment and treatment of unilateral spatial neglect (USN). Current research indicates that VR and ET can provide more naturalistic and sensitive measures, detecting milder forms of USN that conventional tests may miss. Future studies should focus on developing methods for individual subtypes and differential diagnostics to inform personalized treatment programs.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Chemistry, Analytical
Andrea Demeco, Laura Zola, Antonio Frizziero, Chiara Martini, Arrigo Palumbo, Ruben Foresti, Giovanni Buccino, Cosimo Costantino
Summary: In recent years, new technologies, such as fully immersive virtual reality (FIVR), have been applied in stroke rehabilitation alongside conventional techniques. This study aimed to investigate the effectiveness of FIVR in stroke rehabilitation. A total of 12 randomized controlled trials (RCTs) involving 350 post-acute and chronic stroke survivors were included, and the results showed that FIVR provides additional benefits compared to standard rehabilitation, improving upper limb dexterity, gait performance, and dynamic balance, and influencing patient independence. Therefore, FIVR represents a versatile rehabilitation tool that can improve treatment compliance and the functioning and quality of life of stroke survivors.
Article
Neurosciences
Helen Morse, Laura Biggart, Valerie Pomeroy, Stephanie Rossit
Summary: This study investigates end-user perspectives on the use of self-administered VR for spatial neglect rehabilitation. The study finds that clarity of instructions, equipment and technological experience act as barriers to the use of VR for rehabilitation, while performance feedback, engagement, and psychological benefits contribute as facilitators.
NEUROPSYCHOLOGICAL REHABILITATION
(2022)
Article
Medicine, General & Internal
Ho-Suk Choi, Won-Seob Shin, Dae-Hyouk Bang
Summary: The study indicates that the VR-based digital practice program can effectively improve the rehabilitation of unilateral spatial neglect in subacute stroke patients and enhance the recovery of visual perception and head movement.
Review
Clinical Neurology
Lindy J. Williams, Jocelyn Kernot, Susan L. Hillier, Tobias Loetscher
Summary: This scoping review aimed to capture definitions and assessment tools for neglect subtypes post stroke, revealing inconsistency in terminology usage and the challenge of differentiating subtypes with available tools. Clinicians and researchers need to critically evaluate neglect tools for screening and diagnosis.
FRONTIERS IN NEUROLOGY
(2021)
Article
Health Care Sciences & Services
Lilla Alexandra Porffy, Mitul A. Mehta, Joel Patchitt, Celia Boussebaa, Jack Brett, Teresa D'Oliveira, Elias Mouchlianitis, Sukhi S. Shergill
Summary: In this study, a novel virtual reality shopping task called VStore was developed and its construct validity was established by comparing it with the established computerized cognitive battery, Cogstate. The results showed that VStore is sensitive to age-related cognitive decline and engages standard cognitive domains.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Oncology
Florian Bernard, Anne Clavreul, Morgane Casanova, Jeremy Besnard, Jean-Michel Lemee, Gwenaelle Soulard, Renaud Seguier, Philippe Menei
Summary: In awake craniotomy, language and motor functions are often mapped, but more complex functions such as vision and social cognition are less frequently mapped due to the constraints of the surgical environment. This study demonstrates how the use of virtual reality headset with eye tracking can open up new possibilities for mapping these complex functions.
Article
Rehabilitation
Hiu Fung Chan, Manwa Lawrence Ng, HyangHee Kim, Deog Young Kim
Summary: The objective of this study was to evaluate the swallowing-related quality of life of Chinese patients with Parkinson's disease (PD) using the C-SWAL-QOL questionnaire and to identify factors associated with swallowing-related quality of life, including age, disease duration, and depression. The study found that sleep, fatigue, eating duration, and communication were the most severely affected aspects. Depression was significantly related to overall swallowing quality of life, as well as specific subscales such as communication, fear, mental health, social functioning, and fatigue. However, no relationships were found between swallowing quality of life and age or disease duration in PD.
DISABILITY AND REHABILITATION
(2022)
Article
Clinical Neurology
Hyun Haeng Lee, Deog Young Kim, Min Kyun Sohn, Yong-Il Shin, Gyung-Jae Oh, Yang-Soo Lee, Min Cheol Joo, So Young Lee, Junhee Han, Jeonghoon Ahn, Won Hyuk Chang, Ilyoel Kim, Soo Mi Choi, Jongmin Lee, Yun-Hee Kim
Summary: This study validated the proportional recovery model by analyzing the medical records of stroke patients in Korea, identifying clinical factors contributing to the ceiling effect of the Fugl-Meyer Assessment score, and demonstrating variations in recovery proportion based on initial motor deficits of the upper limb. The findings suggest that the proportional recovery model may not be valid for all stroke patients.
Article
Health Care Sciences & Services
Won Hyuk Chang, Jungsoo Lee, Yong-Il Shin, Myoung-Hwan Ko, Deog Young Kim, Min Kyun Sohn, Jinuk Kim, Yun-Hee Kim
Summary: This study aimed to evaluate whether Cerebrolysin combined with rehabilitation therapy supports additional motor recovery in stroke patients. The results showed that the Cerebrolysin group demonstrated less degenerative changes in the major motor-related white matter tracts over time than the placebo group, which has a positive impact on motor recovery in ischemic stroke patients.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Muyul Park, Yejin Cho, Dae Hyun Kim, Hyun Seok Choi, Dong-Hyun Kim, Deog Young Kim
Summary: MWI was used to monitor myelin content changes during rehabilitation in stroke patients, showing significant changes in MWF in the CST. Robot-assisted rehabilitation resulted in a significantly larger MWF change compared to conventional rehabilitation.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Soozy Jung, JiSu Yun, Deog Young Kim, Dong-Hyun Kim
Summary: In this study, an improved MWF mapping method using complex-valued neural network analysis was proposed. The method showed better quantitative results by considering fiber orientation effects and correcting biases and artifacts. Additionally, uncertainty estimates were provided as a confidence interpretation of the output.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Health Care Sciences & Services
Minyoung Shin, Min Kyun Sohn, Jongmin Lee, Deog Young Kim, Yong-Il Shin, Gyung-Jae Oh, Yang-Soo Lee, Min Cheol Joo, So Young Lee, Min-Keun Song, Junhee Han, Jeonghoon Ahn, Young-Hoon Lee, Won Hyuk Chang, Seyoung Shin, Soo Mi Choi, Seon Kui Lee, Yun-Hee Kim
Summary: This study investigated the impact of post-stroke depression (PSD) on cognitive aging in elderly stroke patients. The results showed that early PSD increased the risk of cognitive decline in older stroke patients, mainly in males. Older male patients with negative thinking were at increased risk of cognitive decline, and older women may also be at risk for cognitive decline.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jae-Hun Lee, Jaeuk Yi, Jun-Hyeong Kim, Kanghyun Ryu, Dongyeob Han, Sewook Kim, Seul Lee, Deog Young Kim, Dong-Hyun Kim
Summary: The study demonstrates a joint spatiotemporal reconstruction approach combining JPI and JDL for accelerated 3D mGRE-based MWI, achieving improved reconstruction quality and quantitative values.
Article
Clinical Neurology
Hyun Haeng Lee, Min Kyun Sohn, Deog Young Kim, Yong-Il Shin, Gyung-Jae Oh, Yang-Soo Lee, Min Cheol Joo, So Young Lee, Min-Keun Song, Junhee Han, Jeonghoon Ahn, Young-Hoon Lee, Won Hyuk Chang, Soo Mi Choi, Seon Kui Lee, Jongmin Lee, Yun-Hee Kim
Summary: The study results demonstrate that the proportional recovery model for the lower extremity is invalid.
Article
Environmental Sciences
Eun Young Lee, Min Kyun Sohn, Jong Min Lee, Deog Young Kim, Yong Il Shin, Gyung Jae Oh, Yang Soo Lee, So Young Lee, Min Keun Song, Jun Hee Han, Jeong Hoon Ahn, Young Hoon Lee, Won Hyuk Chang, Soo Mi Choi, Seon Kui Lee, Min Cheol Joo, Yun Hee Kim
Summary: This study investigated the long-term functional changes in patients with moderate-to-severe ischemic stroke and compared the differences between the modified Barthel Index (MBI) and Functional Independence Measure (FIM) according to severity. The results showed that the moderate group had greater recovery in the 3 months after onset compared to the severe group. FIM was found to be more appropriate than MBI for evaluating the functional status of patients with severe stroke.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Seyoung Shin, Yaesuel Lee, Won Hyuk Chang, Min Kyun Sohn, Jongmin Lee, Deog Young Kim, Yong-Il Shin, Gyung-Jae Oh, Yang-Soo Lee, Min Cheol Joo, So Young Lee, Min-Keun Song, Junhee Han, Jeonghoon Ahn, Yun-Hee Kim
Summary: This study observed the long-term changes in functional status and residual disability in survivors of first-time stroke. The results showed that the recovery patterns varied in different functional domains and were influenced by patient age, stroke severity, and stroke type.
Article
Health Care Sciences & Services
Yea Jin Jo, Dae Hyun Kim, Min Kyun Sohn, Jongmin Lee, Yong-Il Shin, Gyung-Jae Oh, Yang-Soo Lee, Min Cheol Joo, So Young Lee, Min-Keun Song, Junhee Han, Jeonghoon Ahn, Won Hyuk Chang, Yun-Hee Kim, Deog Young Kim
Summary: Stroke in young adults has increased and is more likely to be hemorrhagic compared to older adults. Lifestyle-related risk factors such as obesity, smoking, and heavy alcohol consumption are more common in the younger group, while other cardiovascular risk factors are more frequent in the older group.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Rehabilitation
Wonjae Hwang, Seong Min Kang, Sang Yoon Lee, Han Gil Seo, Yoon Ghil Park, Bum Sun Kwon, Kwang Jae Lee, Deog Young Kim, Hyoung Seop Kim, Shi-Uk Lee
Summary: Daewoong botulinum toxin type A (NABOTA) showed significant efficacy and safety in the management of upper limb spasticity in stroke patients.
ANNALS OF REHABILITATION MEDICINE-ARM
(2022)
Article
Neurosciences
Mu Su Kim, Ji Hong Min, Yong-Il Shin, Min Kyun Sohn, Jongmin Lee, Deog Young Kim, Gyung-Jae Oh, Yang Soo Lee, Min Cheol Joo, So Young Lee, Min-Keun Song, Junhee Han, Jeonghoon Ahn, Yun-Hee Kim, Sung-Hwa Ko, Won Hyuk Chang
Summary: Among patients aged <65 years, individuals who consumed alcohol, and those who showed better motor function and fewer comorbidities had a higher quality of life. Among patients aged >65 years, quality of life was higher in males, younger age, married individuals, those with diabetes, and those with a better walking ability. Among male, individuals who consumed alcohol had a higher quality of life. Rehabilitation treatment should prioritize improving modifiable factors to enhance the quality of life in patients with mild stroke.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2023)
Article
Health Care Sciences & Services
Jihyun Park, So Young Joo, Byung-Ok Choi, Dae-Hyun Kim, Jong Bum Park, Jong Weon Lee, Deog Young Kim
Summary: This study evaluated the characteristics of gait patterns in CMT1A patients and classified them according to disease severity. The results showed significant differences in gait parameters between CMT1A patients and healthy controls, as well as variations in gait patterns within different severity groups.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, General & Internal
Junekyung Lee, Min Ho Chun, Young Jin Ko, Shi-Uk Lee, Deog Young Kim, Nam-Jong Paik
Summary: The study aimed to compare the safety and efficacy of MT10107 and OnabotulinumtoxinA in the treatment of post-stroke upper limb spasticity. The results showed no significant difference in safety and efficacy between MT10107 and OnabotulinumtoxinA.