Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction

Selective inhibition of class I but not class IIb histone deacetylases exerts cardiac protection from ischemia reperfusion

(2014) Sverre E. Aune et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Histone Deacetylase (HDAC) 10 Suppresses Cervical Cancer Metastasis through Inhibition of Matrix Metalloproteinase (MMP) 2 and 9 Expression

(2013) Chenlin Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Class I Histone Deacetylase Inhibition Suppresses Hypoxia-Induced Cardiopulmonary Remodeling Through an Antiproliferative Mechanism

(2012) Maria A. Cavasin et al.   CIRCULATION RESEARCH

A Novel Class of Small Molecule Inhibitors of HDAC6

(2011) Elizabeth S. Inks et al.   ACS Chemical Biology

Therapeutic Potential for HDAC Inhibitors in the Heart

(2011) Timothy A. McKinsey   Annual Review of Pharmacology and Toxicology

Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension

(2011) Douglas D. Lemon et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy

(2011) D. J. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted deletion of NF-κB p50 diminishes the cardioprotection of histone deacetylase inhibition

(2010) L. X. Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

(2010) Abishek Iyer et al.   BRITISH JOURNAL OF PHARMACOLOGY

The clinical development of histone deacetylase inhibitors as targeted anticancer drugs

(2010) Paul A Marks   EXPERT OPINION ON INVESTIGATIONAL DRUGS

HDAC Inhibition Attenuates Inflammatory, Hypertrophic, and Hypertensive Responses in Spontaneously Hypertensive Rats

(2010) Jeffrey P. Cardinale et al.   HYPERTENSION

Inhibition of histone deacetylase activity down-regulates urokinase plasminogen activator and matrix metalloproteinase-9 expression in gastric cancer

(2010) Kyung Hee Lee et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Chemical phylogenetics of histone deacetylases

(2010) James E Bradner et al.   Nature Chemical Biology

Two New Pimelic Diphenylamide HDAC Inhibitors Induce Sustained Frataxin Upregulation in Cells from Friedreich's Ataxia Patients and in a Mouse Model

(2010) Myriam Rai et al.   PLoS One

Chemical Probes Identify a Role for Histone Deacetylase 3 in Friedreich's Ataxia Gene Silencing

(2009) Chunping Xu et al.   CHEMISTRY & BIOLOGY

Histone deacetylases facilitate sodium/calcium exchanger up-regulation in adult cardiomyocytes

(2009) Sangeetha Chandrasekaran et al.   FASEB JOURNAL

Directed and Systematic Differentiation of Cardiovascular Cells From Mouse Induced Pluripotent Stem Cells

(2008) Genta Narazaki et al.   CIRCULATION

Activation of Histone Deacetylase 2 by Inducible Heat Shock Protein 70 in Cardiac Hypertrophy

(2008) Hae Jin Kee et al.   CIRCULATION RESEARCH

Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice

(2008) Anne Granger et al.   FASEB JOURNAL

Transcriptional Activation of Human Matrix Metalloproteinase-9 Gene Expression by Multiple Co-activators

(2008) Xueyan Zhao et al.   JOURNAL OF MOLECULAR BIOLOGY

YY1 Protects Cardiac Myocytes from Pathologic Hypertrophy by Interacting with HDAC5

(2008) Carmen C. Sucharov et al.   MOLECULAR BIOLOGY OF THE CELL