Review
Biochemistry & Molecular Biology
Charlotte Delrue, Reinhart Speeckaert, Joris R. R. Delanghe, Marijn M. M. Speeckaert
Summary: Vitamin D is an immune modulator that affects infection susceptibility. The relationship between vitamin D deficiency and mortality in sepsis patients remains unclear. Adequate vitamin D concentration may reduce mortality in sepsis patients with severe deficiency.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Critical Care Medicine
Bora Chae, Yo Sep Shin, Sang Min Kim, Seok-In Hong, Youn-Jung Kim, Seung Mok Ryoo, Won Young Kim
Summary: We investigated the association between vitamin D deficiency and neurologic outcomes after cardiopulmonary resuscitation. The study found that vitamin D deficiency was significantly associated with poor neurological outcomes at 3 months in patients with cardiac arrest.
Article
Nutrition & Dietetics
Hyeri Seok, Jooyun Kim, Won Suk Choi, Dae Won Park
Summary: A prospective cohort study found that severe vitamin D deficiency significantly increased mortality in sepsis patients. Evaluating vitamin D levels in sepsis patients may become necessary in an aging society.
Review
Nutrition & Dietetics
Manuel Rupprecht, Stefan Wagenpfeil, Jakob Schoepe, Reinhold Vieth, Thomas Vogt, Joerg Reichrath
Summary: A meta-analysis was conducted to investigate the impact of oral vitamin D supplementation on serum 25-hydroxyvitamin D levels in healthy adults in Europe. The findings suggest that vitamin D supplementation can significantly increase serum 25(OH)D levels, with the effect influenced by dosage and baseline serum levels.
Article
Nutrition & Dietetics
Zaleha Md Isa, Nor Rumaizah Mohd Nordin, Muhammad Hilmi Mahmud, Syahirah Hashim
Summary: Vitamin D deficiency is prevalent worldwide, including in Malaysia, particularly among females, Indians, and those of Malay ethnicity. It can be managed through pharmacological or non-pharmacological approaches, and prevention methods include adequate intake, sun exposure, or supplementation. Special attention should be given to high-risk groups such as infants, obese patients, and the elderly.
Article
Orthopedics
Yantao Qi, Jixin Chai, Liuyang Zhang, Yong Chen
Summary: This study evaluated the association between preoperative vitamin D levels and postoperative hypocalcaemia after total thyroidectomy. The results showed that preoperative severe vitamin D deficiency was an independent predictive factor for postoperative hypocalcaemia after total thyroidectomy.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Nutrition & Dietetics
Jae-Hun Jung, Eun-Ah Kim, Sang-Yoon Lee, Jung-Eun Moon, Eun-Joo Lee, Sook-Hyun Park
Summary: This study aimed to investigate changes in vitamin D levels and factors associated with vitamin D deficiency (VDD) in Korean preterm infants during the first year of life. The study found a high incidence of VDD in these infants, with vitamin D levels at birth being the strongest predictor of VDD during follow-up. Vitamin D supplementation at 400 IU/day did not affect vitamin D levels during the first year of life. Further research is needed to determine the optimal vitamin D supplementation dose for Korean preterm infants.
Review
Nutrition & Dietetics
Andreea Bianca Stoica, Claudiu Marginean
Summary: This article reviews the impact of vitamin D deficiency on the health of infants, emphasizing its global significance and the need for further research and strategies. While conflicting results exist regarding the effects of vitamin D, it is clear that deficiency has significant implications, particularly for infants.
Article
Multidisciplinary Sciences
Sandra Alvear-Vega, Rodrigo Benavente-Contreras, Hector Vargas-Garrido
Summary: The social determinants associated with Serum 25-hydroxyvitamin D concentrations deficiency in older adults include gender, native origin, urban residence, sunlight exposure, and geographical latitude. Health promotion and prevention programs should be targeted towards older adults in urban areas, with a special focus on women, especially in the southernmost regions.
SCIENTIFIC REPORTS
(2023)
Article
Endocrinology & Metabolism
John D. Sluyter, Yoshihiko Raita, Kohei Hasegawa, Ian R. Reid, Robert Scragg, Carlos A. Camargo
Summary: Using machine learning models to predict vitamin D deficiency showed higher accuracy in predicting 25(OH)D <25 nmol/L compared to traditional models, suggesting a potential role for machine learning models in participant selection for vitamin D supplement trials.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Nutrition & Dietetics
Lei Wang, Jinlu Gan, Jingnan Wu, Yingchun Zhou, Deqiang Lei
Summary: Vitamin D (VitD) insufficiency is a common problem among spinal cord injury (SCI) patients, and low levels of VitD may impair functional restoration after SCI. Studies have shown a high prevalence of VitD insufficiency (81.6%) and deficiency (52.5%) after SCI, along with associations with skeletal diseases, venous thromboembolism, psychoneurological syndromes, and chest illness. Supplemental therapy with VitD has been suggested as a potential adjuvant treatment to accelerate rehabilitation in SCI patients. However, more well-designed trials and experimental research are needed to validate its therapeutic effect, elucidate its neuroprotective mechanism, and develop novel treatments.
FRONTIERS IN NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Jie Chen, Jiao Zhang, Jie Li, Ran Qin, Na Lu, David Goltzman, Dengshun Miao, Renlei Yang
Summary: Emerging observational data suggest that vitamin D deficiency is associated with knee osteoarthritis. However, the relationship between vitamin D level and osteoarthritis, as well as the role of vitamin D supplementation in prevention, are still controversial. This study found that 1,25(OH)2D3 deficiency accelerated the development of knee osteoarthritis in mice, while supplementation with 1,25(OH)2D3 rescued the phenotypes of osteoarthritis.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
(2023)
Review
Nutrition & Dietetics
Szymon Graczyk, Arkadiusz Grzeczka, Urszula Paslawska, Pawel Kordowitzki
Summary: Atrial fibrillation (AF) is a common and severe arrhythmia that can lead to ischemic stroke or heart failure. Vitamin D deficiency has been suggested as a critical factor in the development of AF, particularly after cardiac surgery. Supplementing with vitamin D has been found to reduce the risk of AF in both pre- and postoperative periods. The underlying mechanisms of how vitamin D affects the heart are not fully understood, but it is believed to act through multiple pathways. Despite the correlation between vitamin D deficiency and AF development, the topic is still widely debated and the results are subject to doubt.
Article
Nutrition & Dietetics
Rihwa Choi, Sung-Eun Cho, Sang Gon Lee, Eun Hee Lee
Summary: This retrospective study reviewed the prevalence of vitamin D deficiency in an adult Korean population between 2017 and 2021. The results show a decrease in the overall prevalence of vitamin D deficiency over time. Women were more likely to test their 25(OH)D level and had a higher prevalence of levels below 10 ng/mL compared to men, while their prevalence of levels below 30 ng/mL was lower than that of men. Younger patients had a higher prevalence of levels below 30 ng/mL compared to older patients.
Article
Nutrition & Dietetics
Mario Musella, Giovanna Berardi, Antonio Vitiello, Danit Dayan, Vincenzo Schiavone, Antonio Franzese, Adam Abu-Abeid
Summary: This study aimed to estimate the prevalence of vitamin D deficiency in patients undergoing metabolic bariatric surgery (MBS) and found that preoperative vitamin D deficiency or insufficiency is common in MBS candidates. Early postoperative values of vitamin D were comparable between Sleeve Gastrectomy (SG) and One Anastomosis Gastric Bypass (OAGB).