Article
Multidisciplinary Sciences
Gary M. Wessel, Yuuko Wada, Mamiko Yajima, Masato Kiyomoto
Summary: The study found that Bindin plays a critical role in fertilization in sea urchins, but its function had never been tested. Through gene editing technology, it was successfully demonstrated that Bindin is essential for the binding of sperm and egg cell surfaces.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Environmental Sciences
Orlando J. Luis, Joao M. Gago
Summary: Echinoids have been insufficiently studied in the field of chemoreception due to their sluggish responses to chemical stimuli. By using specific chemical compounds soaked cleaning cloths to chemically stimulate sea urchins, quantitative analyses were made possible, revealing the dependence of their responses on nutritional state and their selective discrimination towards different food-related compounds.
FRONTIERS IN MARINE SCIENCE
(2021)
Review
Cell Biology
Zuoyi Zhou, Jiangshan Zhan, Qingyun Cai, Fanqing Xu, Ruichao Chai, Kalista Lam, Zuo Luan, Guoying Zhou, Sue Tsang, Markus Kipp, Wenling Han, Rong Zhang, Albert Cheung Hoi Yu
Summary: Astrocytes in the brain have important functions in controlling water homeostasis and maintaining the microenvironment. The expression and subcellular localization of aquaporins in astrocytes are closely associated with their physiological and pathophysiological roles. Understanding astrocytes and aquaporins is crucial for comprehending the water distribution system in the brain and the development of related diseases.
Article
Biochemistry & Molecular Biology
Emma Marangon, Sven Uthicke, Frances Patel, Ezequiel M. Marzinelli, David G. Bourne, Nicole S. Webster, Patrick W. Laffy
Summary: This study investigates the microbe-host interactions in a tropical urchin species under climate change scenarios through a 4-year multigenerational experiment. The results show that each life stage and generation is associated with a specific microbiome, and although some changes occur under predicted climate conditions for 2050 and 2100, the life stage specificity is preserved. Furthermore, a climate-mediated parental effect on the offspring microbiome is observed. These findings highlight the potential for cross-generational impacts of climate change on the microbiome of tropical invertebrates.
Review
Physiology
Yanlin Guo, Taotao Luo, Guixiang Xie, Xiaoyan Zhang
Summary: The kidney plays a crucial role in maintaining water and electrolyte balance, with aquaporins being important for water reabsorption. Bile acid receptors have a critical role in urine concentration and show potential therapeutic value for kidney diseases.
FRONTIERS IN PHYSIOLOGY
(2023)
Review
Genetics & Heredity
Abul Kalam Azad, Topu Raihan, Jahed Ahmed, Al Hakim, Tanvir Hossain Emon, Parveen Afroz Chowdhury
Summary: AQPs are integral membrane proteins involved in transmembrane diffusion of water and small solutes bidirectionally. They are functionally diverse and associated with a wide range of non-infectious diseases, while their role in infectious diseases remains to be fully evaluated. Studies suggest that AQPs can be regulated by microbial and parasitic infections, indicating their involvement in microbial pathogenesis, inflammation-related responses, and cell water homeostasis.
FRONTIERS IN GENETICS
(2021)
Article
Multidisciplinary Sciences
Florian Schmitz, Jessica Glas, Richard Neutze, Kristina Hedfalk
Summary: This study introduces a screening approach that utilizes BiFC and flow cytometry to characterize membrane protein interaction partners, allowing for distinguishable constructive complexes from random interactions with statistical confidence. This method potentially enables an efficient high-throughput screen for protein:protein interactions in vivo.
SCIENTIFIC REPORTS
(2021)
Article
Forestry
Zhen Li, Xiaoling Wang, Yunshan Liu, Yangyan Zhou, Zhiliang Qian, Zequn Yu, Na Wu, Zhan Bian
Summary: The effects of nitrogen supply on water uptake, drought resistance, and hormone regulation in Populus simonii seedlings were investigated in this study. The results showed that sufficient nitrogen supply can enhance drought resistance in P. simonii by reducing transpiration rate and reactive oxygen species production while increasing water uptake and antioxidant enzyme activity.
Review
Veterinary Sciences
Lluis Ferre-Dolcet, Maria Montserrat Rivera del Alamo
Summary: The female reproductive tract undergoes structural changes during different reproductive stages, and the expression and location of aquaporins (AQPs) are regulated by ovarian steroid hormones. AQPs play important roles in water and solute transportation, follicular development, lubrication and preparation of the endometrium for embryo implantation and fetal development. In the placenta, AQPs ensure fluid support and fetal homeostasis during pregnancy.
VETERINARY SCIENCES
(2023)
Article
Fisheries
Cheng-Ting Xie, Xin Tu, Ying-Wen Li, Mei-Ling Tan, Qi-Liang Chen, Yan-Jun Shen, Zhi-Hao Liu
Summary: The study aimed to investigate the effect of 17 alpha-ethynylestradiol (EE2) on fish osmoregulation. The results showed that EE2 exposure led to symptoms such as body edema, trichangiectasis in the skin, and protrusion of the proptosis in zebrafish. Furthermore, it significantly affected the condition factor, water weight, water content, RBC count, and HCT. Histopathological damages in the gill and kidney were also observed. The study suggests that EE2 exposure may disrupt water homeostasis in zebrafish. Down-regulation of crh, crhr, and acth mRNA levels in the brain was found, consistent with decreased plasma cortisol levels. In addition, elevated expression of aqp3a and aqp1a1 mRNA levels in the gill and decreased expression of atp1a1a.1 and activity of Na+, K+-ATPase in the gill were observed. Suppressed expression of atp1a1a.4 and activity of Na+, K+-ATPase in the kidney were also present. These changes might be due to decreased plasma cortisol levels and low expression of avp in the brain.
AQUACULTURE RESEARCH
(2022)
Article
Environmental Sciences
L. Palmeira-Pinto, A. K. Emerenciano, E. Bergami, W. R. Joviano, A. R. Rosa, C. L. Neves, I. Corsi, L. F. Marques-Santos, J. R. M. C. Silva
Summary: This study investigated the impact of nano-TiO2 on fertilization, embryonic and larval development of the tropical sea urchin Lytechinus variegatus. Limited toxicity was recorded for nano-TiO2 in sea urchin embryos and larvae, except for effects at the gastrula stage at 0.005μg/mL. Large agglomerates of nano-TiO2 (5μg/mL) were observed adhering onto sea urchin larvae, possibly preventing nanoparticle uptake at the highest concentrations. These findings suggest that environmental levels of nano-TiO2 may have toxicity on tropical sea urchin embryos, with potential consequences on populations and their ecological role in tropical coastal areas.
MARINE ENVIRONMENTAL RESEARCH
(2023)
Review
Cell Biology
Konstantin V. V. Yakovlev
Summary: Unfertilized eggs of animals contain maternal mRNAs and proteins, which are required for the initial stages of embryogenesis. Translation of maternal mRNAs is activated after fertilization, but a low rate of protein synthesis is detected in unfertilized sea urchin eggs.
CELL BIOLOGY INTERNATIONAL
(2023)
Review
Engineering, Environmental
Elham Abaie, Limeimei Xu, Yue-xiao Shen
Summary: Bioinspired and biomimetic membranes have shown remarkable development over the past two decades, taking advantage of exceptional transport properties of biological channels. While commercialized membranes based on AQPs have been successful, large-scale, defect-free biomimetic membranes are still unavailable. The combination of bioinspired concepts, molecular engineering, and collaboration with the polymer industry may lead to scalable polymeric membranes with intrinsic selective channels.
FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Ronja Bihlmaier, Felix Deffner, Ulrich Mattheus, Peter H. Neckel, Bernhard Hirt, Andreas F. Mack
Summary: The choroid plexus is responsible for producing cerebrospinal fluid in the brain ventricles and serves as a blood-CSF barrier. Immunofluorescence and electron microscopy showed that ependymal cells and subependymal astrocytes in the choroid plexus expressed aquaporin-4, which may facilitate water transport. The glial plate surrounding the choroid plexus also demonstrated high AQP4 density, suggesting a possible drainage and clearing pathway for metabolites.
Review
Cell Biology
Moein Ala, Razieh Mohammad Jafari, Asghar Hajiabbasi, Ahmad Reza Dehpour
Summary: Recent research has shown that aquaporins can be used to treat a wider range of diseases beyond diabetes, such as cirrhosis and cancer.
JOURNAL OF CELLULAR PHYSIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Andrea Amaroli, Silvia Ravera, Angelina Zekiy, Stefano Benedicenti, Claudio Pasquale
Summary: Photobiomodulation (PBM) uses non-ionizing light sources in the visible and infrared spectrum to transfer photon energy to cells, energizing molecules and affecting their activity. This review discusses the effect of PBM on oral microbiota and emphasizes the need for further research on light-bacteria interactions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Stefano Aicardi, Matteo Bozzo, Andrea Amaroli, Lorenzo Gallus, Beatrice Risso, Erica Carlig, Davide Di Blasi, Marino Vacchi, Laura Ghigliotti, Sara Ferrando
Summary: This study provides a morphological description of the peripheral olfactory system of the Antarctic silverfish and uses quantitative methods. The head of the Antarctic silverfish is specialized to maintain contact between the olfactory organ and a large volume of water. The fish invests energy in the detection and processing of olfactory signals and relies considerably on olfaction.
Editorial Material
Medicine, General & Internal
Nicola De Angelis, Stefano Benedicenti, Angelina Zekiy, Andrea Amaroli
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Optics
Matteo Bozzo, Claudio Pasquale, Francesco Cuccaro, Sara Ferrando, Angelina Zekiy, Simona Candiani, Andrea Amaroli
Summary: This study evaluated the reliability of photobiomodulation therapy using a novel delivery probe on regenerating amphioxus. The results demonstrated that PBM improved wound healing and tissue regeneration, with daily irradiation showing better outcomes.
Article
Biochemistry & Molecular Biology
Andrea Amaroli, Eleonora Tassara, Sara Ferrando, Stefano Aicardi, Claudio Pasquale, Marco Giovine, Marco Bertolino, Angelina Zekiy, Marina Pozzolini
Summary: The study investigates the effects of photo-biomodulation (PBM) on the regeneration of Chondrosia reniformis. The results show that PBM can accelerate the regeneration process, as evidenced by the upregulation of TGF3, TGF6, and TGF5 genes. The findings suggest that PBM's interaction with cell targets has been conserved throughout the evolution of life forms.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Claudio Pasquale, Nicola De Angelis, Elena Dellacasa, Roberto Raiteri, Fabrizio Barberis, Alberto Lagazzo, Stefano Benedicenti, Andrea Amaroli
Summary: This study investigates the effects of laser irradiation on titanium against peri-implant infection and suggests choosing a laser that causes less damage to titanium implants. In the past decade, there has been a significant increase in dental implants, leading to a rise in peri-implantitis cases. Laser therapy has become one of the preferred treatments for peri-implantitis. However, the type of laser used can impact the success of the therapy. The aim of this comparative experimental work was to compare the effects of the most commonly used lasers on grade 4 titanium surfaces, considering any structural damage they may cause. The results show that the 1064-nm Q-switch Nd:YAG nanosecond pulsed laser is more suitable for preserving implant morphology without inducing metal damage.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemistry & Molecular Biology
Adnan S. Syed, Kanika Sharma, Maxime Policarpo, Sara Ferrando, Didier Casane, Sigrun Korsching
Summary: Cartilaginous fishes have a low and stable number of olfactory chemosensory receptors belonging to the OR, TAAR, and V1R/ORA families, while the number of V2R/OlfC receptors is higher and more dynamic. The V2R/OlfC receptors are expressed in the olfactory epithelium in a sparse pattern, indicating the same cell-type specificity as bony fishes. The relatively low number of olfactory receptors in cartilaginous fishes compared to bony fishes may be due to a trade-off between olfactory sensitivity and discrimination capability.
MOLECULAR BIOLOGY AND EVOLUTION
(2023)
Article
Medicine, General & Internal
Alberto Materni, Claudio Pasquale, Antonio Signore, Stefano Benedicenti, Andrea Amaroli
Summary: This study proposed a novel surgical approach, termed single incision access (SIA), for extracting impacted inferior third molars. Compared to the previously described flapless surgical approach (FSA), the SIA method demonstrated faster healing time after the extraction of impacted molars. The FSA approach also showed benefits in reducing swelling and pain and improving gum health.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cell Biology
Matteo Bozzo, Deianira Bellitto, Andrea Amaroli, Sara Ferrando, Michael Schubert, Simona Candiani
Summary: POU genes are a conserved family of transcription factors that play key roles in cell type specification and neurogenesis. This study aimed to investigate the role of retinoic acid (RA) signaling in the regulation of POU genes. Using amphioxus as a model, the expression patterns of POU genes were examined during development. It was found that RA signaling regulates the expression of Brn1/2/4 and Pou4 genes in specific tissues, indicating a dual role of RA signaling in providing patterning information and specifying neural cell types.
Article
Polymer Science
Alberto Materni, Claudio Pasquale, Eugenio Longo, Massimo Frosecchi, Stefano Benedicenti, Matteo Bozzo, Andrea Amaroli
Summary: Tooth extraction leads to complex local changes in both hard and soft tissues. Dry socket (DS) is a common complication, with an incidence ranging from 1-4% after generic tooth extraction to 45% for mandibular third molars. This study investigated the preventive effect of sunflower oil-based ozone gel Ozosan((R)) on DS. Results showed a significant reduction in DS incidence from 21.5% to 2% after inferior third molar extraction with Ozosan((R)).
Article
Biochemistry & Molecular Biology
Chiara Cervetto, Andrea Amaroli, Sarah Amato, Elena Gatta, Alberto Diaspro, Guido Maura, Antonio Signore, Stefano Benedicenti, Manuela Marcoli
Summary: Increasing evidence suggests that photobiomodulation, using photons in the red to near-infrared spectrum, may be effective for treating central nervous system disorders. However, the mechanisms underlying the effects of photobiomodulation on glutamate release are still unclear.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Claudio Pasquale, Nicola De Angelis, Fabrizio Barberis, Alberto Lagazzo, Elena Dellacasa, Davide Biggio, Matteo Schiaffino, Roberto Raiteri, Luca Ceseracciu, Stefano Benedicenti, Andrea Amaroli
Summary: This study compared the whitening effectiveness and potential structural changes of four different teeth whitening products. The results showed that all tested bleaching agents had whitening effects, with BlancOne ULTRA(+) demonstrating the most effective whitening and least structural changes, making it the most cost-effective choice.
APPLIED SCIENCES-BASEL
(2023)
Editorial Material
Medicine, General & Internal
Nicola De Angelis, Francesco Bagnasco, Andrea Amaroli
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cell Biology
Abril Alondra Barrientos-Bonilla, Paola Belem Pensado-Guevara, Abraham Puga-Olguin, Rasajna Nadella, Aurora del Carmen Sanchez-Garcia, Laura Mireya Zavala-Flores, Arnulfo Villanueva-Olivo, Iliana Tamara Cibrian-Llanderal, Maria de Jesus Rovirosa-Hernandez, Daniel Hernandez-Baltazar
Summary: This study evaluated the impact of BrdU on liver function and found that multiple injections of BrdU did not induce hepatocellular damage.
Article
Cell Biology
Pan Zhang, Qun Feng, Wenxiao Chen, Xizhuang Bai
Summary: It was found that catalpol antagonizes LPS-mediated inflammation and suppressive osteoblast differentiation by inhibiting inflammation and promoting osteoblast differentiation. This finding contributes to a better understanding of the pathogenesis of osteoporosis.
