High circulating irisin levels are associated with insulin resistance and vascular atherosclerosis in a cohort of nondiabetic adult subjects

The inflammatory status score including IL-6, TNF-α, osteopontin, fractalkine, MCP-1 and adiponectin underlies whole-body insulin resistance and hyperglycemia in type 2 diabetes mellitus

(2013) G. Daniele et al.   ACTA DIABETOLOGICA

Insulin clearance is associated with carotid artery intima–media thickness

(2013) Maria A. Marini et al.   ATHEROSCLEROSIS

Serum irisin levels in new-onset type 2 diabetes

(2013) Yeon-Kyung Choi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Pioglitazone improves glucose metabolism and modulates skeletal muscle TIMP-3–TACE dyad in type 2 diabetes mellitus: a randomised, double-blind, placebo-controlled, mechanistic study

(2013) Devjit Tripathy et al.   DIABETOLOGIA

Circulating Irisin in Relation to Insulin Resistance and the Metabolic Syndrome

(2013) Kyung Hee Park et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin Resistance

(2013) José María Moreno-Navarrete et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Lower circulating irisin is associated with type 2 diabetes mellitus

(2013) Jian-Jun Liu et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Common Genetic Variation in the Human FNDC5 Locus, Encoding the Novel Muscle-Derived ‘Browning’ Factor Irisin, Determines Insulin Sensitivity

(2013) Harald Staiger et al.   PLoS One

Decreased Insulin Clearance in Individuals with Elevated 1-h Post-Load Plasma Glucose Levels

(2013) Maria Adelaide Marini et al.   PLoS One

Insulin Sensitivity,  -Cell Function, and Incretin Effect in Individuals With Elevated 1-Hour Postload Plasma Glucose Levels

(2012) M. A. Marini et al.   DIABETES CARE

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise

(2012) Joo Young Huh et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Is irisin a human exercise gene?

(2012) James A. Timmons et al.   NATURE

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Muscles, exercise and obesity: skeletal muscle as a secretory organ

(2012) Bente K. Pedersen et al.   Nature Reviews Endocrinology

Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity – Correlation with body mass index

(2012) Andreas Stengel et al.   PEPTIDES

Activation of PPARγ induces profound multilocularization of adipocytes in adult mouse white adipose tissues

(2010) Young Jun Koh et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Elevated one-hour post-load plasma glucose levels identifies subjects with normal glucose tolerance but early carotid atherosclerosis

(2009) E. Succurro et al.   ATHEROSCLEROSIS

Harmonizing the Metabolic Syndrome

(2009) K.G.M.M. Alberti et al.   CIRCULATION

Impact of Body Mass Index and the Metabolic Syndrome on the Risk of Cardiovascular Disease and Death in Middle-Aged Men

(2009) Johan Ärnlöv et al.   CIRCULATION

Single-Nucleotide Polymorphism rs7754840 ofCDKAL1Is Associated with Impaired Insulin Secretion in Nondiabetic Offspring of Type 2 Diabetic Subjects and in a Large Sample of Men with Normal Glucose Tolerance

(2008) Alena Stančáková et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM