Article
Neurosciences
Julia Fietz, Dorothee Poehlchen, Florian P. Binder, Michael Czisch, Philipp G. Saemann, Victor Spoormaker
Summary: The diameter of the human pupil can track working memory processing, with recent research showing a connection to activity in both the frontoparietal network and the salience network. The combination of pupil measurements and fMRI can be a valuable tool for dissecting subprocesses related to working memory load and stimulus salience.
HUMAN BRAIN MAPPING
(2022)
Article
Neuroimaging
Antonia Kaiser, Liesbeth Reneman, Paul J. Lucassen, Taco J. de Vries, Anouk Schrantee, Anne Marije Kaag
Summary: The study examined the neural mechanisms underlying the interaction between working memory (WM) and emotional reactivity (ER) in adult ADHD participants, finding that taxing WM reduced reactivity to emotional stimuli in heavy drinkers but did not affect neural correlates of ER in ADHD participants. No impairments in WM or ER were found in the ADHD group, possibly due to the relatively unimpaired ADHD population and well-matched control group. Further investigation is needed to determine if targeting WM may be effective in participants with severe ER impairments in ADHD.
BRAIN IMAGING AND BEHAVIOR
(2022)
Article
Psychiatry
Norma Verdolini, Silvia Alonso-Lana, Pilar Salgado-Pineda, Salvador Sarro, Raymond Salvador, Teresa Maristany, Jose M. Goikolea, Caterina M. Bonnin, Ines Martin, Laura Salo, Ana Romaguera, Elena Rodriguez-Cano, Adriane R. Rosa, Eduard Vieta, Edith Pomarol-Clotet
Summary: This study aimed to assess the brain functional correlates of psychosocial functioning in individuals with bipolar disorder during a working memory task. The results revealed differences in brain activation between bipolar patients and healthy controls, particularly in the medial frontal cortex. In addition, the study found inverse correlations between psychosocial functioning and brain activation in several cortical regions, including the frontal, parietal, and temporo-occipital regions.
PSYCHIATRY RESEARCH
(2023)
Article
Neurosciences
Yu Xiao, Ying Lin, Junji Ma, Jiehui Qian, Zijun Ke, Liangfang Li, Yangyang Yi, Jinbo Zhang, Cam-CAN, Zhengjia Dai
Summary: This study utilized multimodal neuroimaging and machine learning to investigate the neural mechanism of visual working memory in a large cohort of 547 individuals. The findings revealed significant predictors within specific neural networks for VWM and confirmed the specificity of these predictors compared to emotional regulation and fluid intelligence. The results provide a solid foundation for understanding cognitive functions with a multimodal approach.
HUMAN BRAIN MAPPING
(2021)
Article
Clinical Neurology
Xenia Kobeleva, Judith Machts, Maria Veit, Stefan Vielhaber, Susanne Petri, Mircea Ariel Schoenfeld
Summary: This fMRI study on ALS patients found significantly increased brain activity in the frontotemporal and parietal regions during working memory tasks, which was associated with better neuropsychological function within the patient group. The results suggest a compensatory effect in ALS patients during working memory execution.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Biology
Andrea Ciorba, Stavros Hatzopoulos, Cristina Cogliandolo, Chiara Bianchini, Martina Renna, Luca Perrucci, Magdalena Skarzynska, Piotr Henryk Skarzynski, Paolo Campioni, Corrado Cittanti, Aldo Carnevale, Melchiore Giganti, Stefano Pelucchi
Summary: The study utilized fMRI to evaluate brain maps generated from healthy individuals' response to olfactory stimuli, revealing that the left anterior insula is primarily activated by odorous stimuli and other cortical areas are also involved.
Article
Neurosciences
Xin Zhang, Jiayue Liu, Yang Yang, Shijie Zhao, Lei Guo, Junwei Han, Xintao Hu
Summary: The study examined the test-retest reliability of dynamic functional connectivity (dFC) in functional magnetic resonance imaging (fMRI) under natural viewing condition, revealing significantly improved reliability compared to resting state. This suggests that naturalistic paradigms may enhance the study of functional brain networks using fMRI.
HUMAN BRAIN MAPPING
(2022)
Review
Behavioral Sciences
Sophia Linguiti, Jacob W. Vogel, Valerie J. Sydnor, Adam Pines, Nick Wellman, Allan Basbaum, Claudia R. Eickhoff, Simon B. Eickhoff, Robert R. Edwards, Bart Larsen, Andrew McKinstry-Wu, J. Cobb Scott, David R. Roalf, Vaishnavi Sharma, Eric C. Strain, Gregory Corder, Robert H. Dworkin, Theodore D. Satterthwaite
Summary: Functional magnetic resonance imaging (fMRI) is increasingly used to study the acute impact of psychedelics on the human brain. A systematic review of fMRI studies revealed substantial heterogeneity in design and methodology. However, the review identified consistent findings: psilocybin and LSD modulate connectivity in the sensorimotor-association cortical axis, while ketamine increases activation in the dorsomedial prefrontal cortex.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Neurosciences
Chia-Hsin Yin, Fan-Pei Gloria Yang
Summary: This study investigates the role of working memory capacity in metaphoric and metonymic processing in Mandarin-English bilinguals, as well as the neural correlations between metaphor and metonymy computations. The findings suggest that similar brain regions are activated during figurative language processing and that better working memory capacity bilinguals use more inhibitory control mechanisms in metonymic processing.
Review
Endocrinology & Metabolism
Ziqi Zhang, Yu Chen, Xiqiao Zhou, Su Liu, Jiangyi Yu
Summary: This study searched the literature on functional magnetic resonance imaging (fMRI) for the assessment of renal alterations in diabetic kidney disease. 24 publications were included in the study, with a total of 1550 subjects. The study found that renal blood flow (RBF) values were significantly lower in the DKD group compared to the HV group on ASL-MRI. The FA values were also significantly lower in the DKD group on DTI-MRI. There were no significant differences in the other parameters on BOLD-MRI or IVIM-DWI.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Behavioral Sciences
Shanna Kousaie, Jen-Kai Chen, Shari R. Baum, Natalie A. Phillips, Debra Titone, Denise Klein
Summary: This study examined the impact of language learning timing on bilinguals' phonological and non-verbal working memory performance and neural correlates. Despite similar behavioral performance, different groups showed differences in neural recruitment patterns during task performance, indicating a specific effect of language learning timing on executive function related to language.
Article
Neurosciences
Gabriele Russo, Xavier Helluy, Mehdi Behroozi, Denise Manahan-Vaughan
Summary: The study proposes a habituation strategy for awake rats undergoing fMRI, which enables stable image acquisition with low motion artifacts by gradually training the rats over a period of three weeks. Effective habituation results in low stress levels and minimal head motion artifacts during fMRI, allowing for precise brain mapping of BOLD signals and supporting the discrimination of cognitive processes without stress confounds.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Psychology, Clinical
Taylor Hatchard, Aziza Byron-Alhassan, Ola Mioduszewski, Katherine Holshausen, Stacey Correia, Allison Leeming, Gladys Ayson, Carley Chiasson, Peter Fried, Ian Cameron, Andra Smith
Summary: This study utilized fMRI to examine neural activation and performance on a working memory task in young adults. While there were no differences in performance, cannabis users showed significant differences in brain activation, including altered functional connectivity. This suggests potential compensatory mechanisms in the brain due to sustained cannabis use.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2021)
Article
Integrative & Complementary Medicine
Xingjie Li, Qiqi Liu, Rui Xia, Jun Liu, Dan Wang, Jiao Shi, Yuxing Kuang, Yalan Dai, Haoyu Huang, Wei Tang, Shangjie Chen
Summary: The objective of this study was to investigate the correlation between changes in brain activity associated with working memory and assessment scales of memory scores in amnestic mild cognitive impairment (aMCI) before and after moxibustion therapy. The results showed that moxibustion treatment improved memory in aMCI patients and was associated with the activation of specific brain regions, which may be an important mechanism by which moxibustion improves memory function.
JOURNAL OF TRADITIONAL CHINESE MEDICINE
(2023)
Article
Clinical Neurology
Maryam Alsameen, Mark W. DiFrancesco, Sean P. A. Drummond, Peter L. Franzen, Dean W. Beebe
Summary: Sleep deprivation can lead to disruptions in adolescents' working memory, with compensatory increased responses in brain networks when task performance degrades. Chronic sleep restriction may result in greater activation in the medial prefrontal cortex and weaker activation in the precuneus during the most difficult task conditions, along with compensatory functional responses in brain regions processing sensory input and vigilance. Adolescents under chronic sleep restriction show impaired performance and diminished brain responses during the most challenging task levels.
JOURNAL OF SLEEP RESEARCH
(2021)
Review
Biotechnology & Applied Microbiology
Shanquan Wang, Yixuan Wang, Xiaosong He, Qihong Lu
Summary: The fate of organic pollutants can be determined by degradation and humification. The potential of humification process for removal of resistant organic pollutants has been underestimated. The recent progress in synthesizing artificial humic substances has made targeted humification of recalcitrant organic pollutants possible.
TRENDS IN BIOTECHNOLOGY
(2022)
Article
Biology
Aswin Chari, Kiran K. Seunarine, Xiaosong He, Martin M. Tisdall, Christopher A. Clark, Dani S. Bassett, Rod C. Scott, Richard E. Rosch
Summary: Network control theory is used to model the neurophysiological dynamics of the brain based on the structural connectome constructed from diffusion MRI. This study explores the changes in average and modal controllability in children with drug-resistant epilepsy compared to healthy controls. The results suggest that increased thalamocortical connectivity may be responsible for the observed changes in controllability. The findings also indicate that controllability changes can be used as a manifestation of brain network dysfunction in epilepsy and may help in understanding the pathophysiology of the disease.
COMMUNICATIONS BIOLOGY
(2022)
Article
Environmental Sciences
Lei Jiang, Yi-Xuan Chu, Xuan Zhang, Jing Wang, Xiaosong He, Chen-Yang Liu, Ting Chen, Ruo He
Summary: This study investigated the anaerobic oxidation of methane (AOM) activity and communities of methane-oxidizing bacteria in three informal landfills. The AOM rate was highest in the landfill with aeration, and the NO2--N content was positively correlated with the AOM rate. Gamma-Proteobacteria methanotrophs, especially Methylobacter, were abundant in the landfilled waste. The relative abundance of various methanotrophs was positively correlated with the contents of NO2--N in the landfilled waste samples.
ENVIRONMENTAL RESEARCH
(2022)
Article
Oncology
Guangxu Xuan, Xin Zhang, Min Zhang, Minghang Yu, Yujie Zhou, Xiaosong He, Xiaopeng Hu, Xi Wang, Liangfa Liu
Summary: This study found that the expression of NTF2 was significantly increased in HNSCC tissue and high expression levels were associated with poor prognosis. NTF2 was found to be involved in epithelial cell growth, skin differentiation, keratosis, and estrogen metabolism. The expression of NTF2 was negatively correlated with immune infiltrations and correlated with immune checkpoint blockade responses. Experimental verifications confirmed the promoting effects of NTF2 on the proliferation and migration of tumor cells.
FRONTIERS IN ONCOLOGY
(2022)
Article
Environmental Sciences
Jiajun Ou, Junlin Wen, Wenbing Tan, Xiaoshan Luo, Jiexuan Cai, Xiaosong He, Lihua Zhou, Yong Yuan
Summary: Linear and nonlinear models were used to monitor the structure dependence of humic substances (HS) redox activities. The PLS model showed moderate ability, while the ANN model achieved higher performance. Sensitivity analysis confirmed the accuracy of the models and provided a potential approach for studying the structure-activity relationships of HS.
ENVIRONMENTAL RESEARCH
(2023)
Review
Environmental Sciences
Chenghao Huang, Nannan Yuan, Xiaosong He, Changhui Wang
Summary: The use of ceramsite as a filtration material in water treatment is popular, and the development of low-cost, high-performance, and environmentally friendly ceramsites has gained attention. This study focuses on exploring the use of drinking water treatment residue (DWTR) to make ceramsite for water treatment. The results show that DWTR-based ceramsites can be fabricated using sintering and non-sintering methods. Further research is needed to evaluate the performance and potential for pollution control of DWTR-based ceramsite-constructed filtration systems, as well as the stability and safety of raw DWTR-based ceramsite.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Neurosciences
Sana Hussain, Jason Langley, Aaron R. R. Seitz, Xiaoping P. P. Hu, Megan A. K. Peters
Summary: Hidden Markov Models (HMMs) are commonly used to analyze neuroimaging data and identify recurring patterns. However, most existing HMMs define states based on activity levels rather than functional connectivity patterns. In this study, we introduced a new HMM that defines states based on full functional connectivity profiles, which outperformed previous methods in accurately identifying connectivity states.
BRAIN CONNECTIVITY
(2023)
Article
Environmental Sciences
Xiaowei Wang, Hongwei Zhang, Xiaosong He, Jianfei Liu, Zhiliang Yao, Hongbin Zhao, Dayang Yu, Baosen Liu, Tianfu Liu, Weilong Zhao
Summary: Limited information on contamination of PFASs from agricultural activities in water sources. Investigated PFASs contamination in agricultural groundwater and nearby surface water in North China. Found higher PFAS concentrations in surface water, indicating migration from surface to groundwater. Found significant correlations between PFASs and organic carbon/nutrients in water. Health risk assessment showed no significant harm to residents in the studied area. Provided information on sources and migration characteristics of PFASs in a typical agricultural area of North China.
FRONTIERS IN ENVIRONMENTAL SCIENCE
(2023)
Review
Environmental Sciences
Qi Pan, Qing-Yu Liu, Jing Zheng, Yan-Hong Li, Song Xiang, Xiao-Jie Sun, Xiao-Song He
Summary: Gas emitted from landfills contains a large quantity of volatile organic compounds (VOCs) and semi-volatile organic compounds (SVOCs), some of which are carcinogenic, teratogenic, and mutagenic. The global hazards of VOCs and SVOCs in landfill gas to human health remain unclear. To quantify the global risk distributions of these pollutants, the composition and concentration data of VOCs and SVOCs from 72 landfills in 20 countries were collected and their human health risks were assessed. Organic compounds in landfill gas primarily result from the biodegradation of natural organic waste or the emissions and volatilization of chemical products. The respiratory system, particularly the lung, was found to be the major target organ of VOCs and SVOCs, with additional adverse health impacts ranging from headache and allergies to lung cancer. Aromatic and halogenated compounds were the primary sources of health risk, while ethyl acetate and acetone from the biodegradation of natural organic waste also exceeded the acceptable levels for human health. Overall, VOCs and SVOCs affected residents within 1,000 m of landfills. Air temperature, relative humidity, air pressure, wind direction, and wind speed were the major factors that influenced the health risks of VOCs and SVOCs. Currently, landfill risk assessments of VOCs and SVOCs are primarily based on respiratory inhalation, with health risks due to other exposure routes remaining poorly elucidated. In addition, potential health risks due to the transport and transformation of landfill gas emitted into the atmosphere should be further studied.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Neurosciences
Kaiqing Chen, Xiaoping Hu
Summary: Intranasal administration of creatine increases brain creatine levels and improves cognitive performance in rats, while oral administration and control groups did not show the same effect.
BRAIN RESEARCH BULLETIN
(2023)
Article
Multidisciplinary Sciences
Panagiotis Fotiadis, Matthew Cieslak, Xiaosong He, Lorenzo Caciagli, Mathieu Ouellet, Theodore D. Satterthwaite, Russell T. Shinohara, Dani S. Bassett
Summary: Recent work has found that the relationship between structural and functional connectivity in the human brain varies across different regions, with reduced connectivity observed in the sensory-association cortical hierarchy. This study suggests that intracortical myelination and excitation-inhibition balance play a role in mediating the heterogeneous expression and temporal variance of structure-function coupling.
NATURE COMMUNICATIONS
(2023)
Article
Neurosciences
Amanda L. McGowan, Linden Parkes, Xiaosong He, Ovidia Stanoi, Yoona Kang, Silicia Lomax, Mia Jovanova, Peter J. Mucha, Kevin N. Ochsner, Emily B. Falk, Dani S. Bassett, David M. Lydon-Staley
Summary: This study examines the relationship between brain structure and negative affect variability in daily life using network control theory. The results suggest that high average controllability of the cingulo-insular system is associated with increased negative affect variability.
BIOLOGICAL PSYCHIATRY: GLOBAL OPEN SCIENCE
(2022)
Proceedings Paper
Engineering, Industrial
Shangzhu Jin, Qingxia Li, Xiaosong He, Jun Peng, Ke Xu, Ning Chen, Haojun Dai
Summary: This paper proposes a personalized recommendation method based on heterogeneous information networks, which improves the performance of the recommender system by integrating multiple meta-paths. The experimental results demonstrate its superiority.
2022 IEEE 17TH CONFERENCE ON INDUSTRIAL ELECTRONICS AND APPLICATIONS (ICIEA)
(2022)
Meeting Abstract
Clinical Neurology
L. Caciagli, C. Paquola, X. He, C. Vollmar, M. Centeno, B. Wandschneider, U. Braun, K. Trimmel, S. B. Vos, M. K. Sidhu, P. J. Thompson, S. Baxendale, G. P. Winston, J. S. Duncan, D. S. Bassett, M. J. Koepp, B. C. Bernhardt
Article
Environmental Sciences
Bi-Cun Jiang, Ye-Chao Tian, Wen-Xiang Ji, Min-Hui Cai, Yu-Ze Han, Yan-Ting Zuo, Chen-Dong Shuang, Xiao-Song He, Fu-Qiang Liu, Wen-Tao Li, Ai-Min Li
Summary: This study identified a unique fluorescent tracer from landfill leachate that could be used for monitoring groundwater contamination. Through principal factor analysis, groundwater samples were successfully clustered into two groups, with Group II showing the characteristic fluorescence tracer of landfill leachate contamination, indicating pollution risks.