Article
Nutrition & Dietetics
Konstantin Tziridis, Holger Schulze
Summary: This study investigated the preventive and curative effects of Ginkgo biloba extract EGb 761(R) on noise-induced synaptopathy, hearing loss, and tinnitus development. The results showed that EGb 761(R) had a clear preventive effect on ribbon synapse loss and reduced hearing loss and tinnitus. However, it did not have a curative effect on ribbon synapse loss and did not significantly affect tinnitus development.
Article
Plant Sciences
Zarko Kulic, Thomas Ritter, Birgit Roeck, Jens Elsaesser, Heike Schneider, Stefan Germer
Summary: The Ginkgo extract EGb 761, produced with leaves of Ginkgo biloba, is a clinically proven remedy for improving age-associated cognitive impairment and quality of life in patients with mild dementia. The study focused on the structural class of proanthocyanidins in EGb 761, showing that it contains delphinidin and cyanidin as main building blocks.
Review
Pharmacology & Pharmacy
Zarko Kulic, Martin D. Lehner, Gunnar P. H. Dietz
Summary: The phytochemical composition of extracts derived from the same plant can vary significantly, affecting their pharmacokinetic and pharmacodynamic properties, and ultimately their clinical efficacy and safety. Regulating active constituent levels and reducing undesired substances is vital for ensuring the quality and consistency of herbal extracts. The heterogeneity of extracts should be carefully considered when evaluating the efficacy and safety of plant-derived remedies.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Chemistry, Medicinal
Carlo Tomino, Sara Ilari, Vincenzo Solfrizzi, Valentina Malafoglia, Guglielmo Zilio, Patrizia Russo, Stefania Proietti, Federica Marcolongo, Giovanni Scapagnini, Carolina Muscoli, Paolo Maria Rossini
Summary: Ginkgo biloba leaf special extract EGb 761(R) has demonstrated effectiveness in improving cognitive function and neuropsychiatric symptoms in patients with age-related cognitive decline, MCI, and mild to moderate dementia, reducing caregiver stress and maintaining patient autonomy. Further evidence is needed to evaluate the role of EGb 761(R) in combination therapy with anti-dementia drugs.
Article
Neurosciences
Ishak Suat Ovey, Ahmet Ozsimsek, Halil Aziz Velioglu, Ozlem Altay, Adil Mardinoglu, Burak Yulug
Summary: This study aimed to investigate the effects of EGb 761 on a controlled model of pentylenetetrazole-induced generalized epilepsy. The results showed that EGb 761 reduced Ca release, restored apoptosis, ROS changes, mitochondrial depolarization and caspase levels, suggesting its prophylactic and therapeutic effects. It is the first study to investigate the combined effects of EGb 761 and pentylenetetrazole on TRP channels in a relevant model of human epileptic diseases.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2023)
Article
Plant Sciences
Rania A. Abdel-Emam, Ahmed M. Abd-Eldayem
Summary: This study compared the effects of Egb-761 and dexamethasone on carrageenan-induced hind paw inflammation in rats, showing that both treatments significantly reduced paw edema and tissue levels of MDA, NO, and TNF-alpha. Dexamethasone demonstrated slightly superior anti-inflammatory and antioxidant efficacy compared to Egb-761.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Pharmacology & Pharmacy
Robert Hoerr, Andrea Zimmermann, Friedeborg Seitz, Angelika Dienel
Summary: The study confirmed that both single and repeated doses of EGb 761 (R) do not impact the plasma concentrations of rivaroxaban or anti-Factor Xa activity in healthy subjects, and the treatments are safe and well-tolerated.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Pharmacology & Pharmacy
Mei Cui, Tongyao You, Yuwu Zhao, Ruozhuo Liu, Yangtai Guan, Jianren Liu, Xueyuan Liu, Xin Wang, Qiang Dong
Summary: This study investigated the cognitive effects of EGb 761 (R) treatment in patients after acute ischemic stroke. The results showed that EGb 761 (R) treatment significantly improved overall cognitive function, especially in language learning and shape tracking. This suggests that EGb 761 (R) treatment has a positive effect on improving cognitive function in stroke patients.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Medicine, Research & Experimental
Dina F. Mansour, Dalia O. Saleh, Omar A. Ahmed-Farid, Mona Rady, Rofanda M. Bakeer, Ingy M. Hashad
Summary: Experimental results confirmed the protective effect of Ginkgo biloba extract (EGb 761) on MTX-induced testicular injury, as evidenced by reduced oxidative stress, improved energy functions, alleviated sperm abnormalities, and preserved spermatogenesis.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Biochemistry & Molecular Biology
Ahmed M. Abd-Eldayem, Sulaiman Mohammed Alnasser, Hanan H. Abd-Elhafeez, Soha A. Soliman, Rania A. Abdel-Emam
Summary: The standardized Ginkgo biloba leaf extract (EGb 761) has antioxidant and anti-inflammatory properties, providing both preventative and therapeutic benefits for indomethacin-induced gastric ulcers. EGb 761 reduces ulcer damage, oxidative and inflammatory damage, and decreases inflammation in the gastric mucosa.
Article
Plant Sciences
Jiajia Zhao, Kun Li, Yingying Wang, Dan Li, Qianwen Wang, Shengsheng Xie, Jianxin Wang, Zhong Zuo
Summary: The study found that co-treatment of EGb 761 and donepezil significantly improved cognitive function, increased brain levels of superoxide dismutase, and decreased brain levels of acetylcholinesterase and malondialdehyde in scopolamine-induced cognitive impairment rats. Despite these beneficial pharmacodynamic outcomes, the co-treatment did not alter the plasma pharmacokinetics and brain uptake of donepezil or bilobalide.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Review
Food Science & Technology
Xuan Chen, Hongyan Li, Bing Zhang, Zeyuan Deng
Summary: Frequent intake of whole foods and dietary food variety is recommended for health benefits, as it can help prevent various chronic diseases. The interactive effects of phytochemicals in whole foods are more effective for health than individual dietary supplements, but the specific mechanisms of interaction are still unclear.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Afsheen Ayaz, QurratUlAin Jamil, Musaddique Hussain, Fayyaz Anjum, Adeel Sarfraz, Taha Alqahtani, Nadia Hussain, Reem M. Gahtani, Ayed A. Dera, Hanan M. Alharbi, Shahid M. Iqbal
Summary: Sf.Cr, an extract from Suaeda fruticosa, shows significant gastroprotective activity by reducing gastric ulcer severity and increasing ulcer inhibition rate, along with antioxidant, anti-secretory, and cytoprotective effects.
Review
Clinical Neurology
Jakub Hort, Thomas Duning, Robert Hoerr
Summary: This systematic review aimed to provide an overview of clinical trials of Ginkgo biloba extract EGb 761 in patients with mild Neurocognitive Disorder (mild NCD) according to DSM-5 criteria. The results showed that EGb 761 had beneficial effects on cognitive deficits and neuropsychiatric symptoms in patients with mild NCD. The drug was found to be safe and well tolerated.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2023)
Article
Chemistry, Analytical
Likun Huang, Jingshi Yang, Zhishan Liang, Ruilian Liang, Hui Luo, Zhonghui Sun, Dongxue Han, Li Niu
Summary: Sesamol (SM) is a natural antioxidant that can improve memory and cognitive impairment in Alzheimer's disease patients. A ternary heterojunction photoelectrochemical (PEC) sensor was constructed to detect SM and its synergistic interactions with other antioxidants.
Article
Chemistry, Applied
Ziwen Luo, Shanshan Wang, Dongmei Wang
NATURAL PRODUCT RESEARCH
(2016)
Article
Pharmacology & Pharmacy
Hao Lu, Feng Ma, Huan Wang, Peng-shuai Geng, Shan-shan Wang, Jian-guo Wang, Chen-chen Wu, Bao-yu Zhao
Article
Integrative & Complementary Medicine
Shan-Shan Wang, Dong-Mei Wang, Wen-Jun Pu, Deng-Wu Li
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2013)
Article
Veterinary Sciences
Hao Lu, Liang Zhang, Shan-shan Wang, Wen-long Wang, Bao-yu Zhao
BMC VETERINARY RESEARCH
(2013)
Review
Environmental Sciences
Wu Chenchen, Wang Wenlong, Liu Xiaoxue, Ma Feng, Cao Dandan, Yang Xiaowen, Wang Shanshan, Geng Pengshuai, Lu Hao, Zhao Baoyu
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2014)
Article
Agriculture, Multidisciplinary
Hao Lu, Shan-shan Wang, Wen-long Wang, Liang Zhang, Bao-yu Zhao
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2014)
Review
Ecology
Hao Lu, Dan Dan Cao, Feng Ma, Shan Shan Wang, Xiao Wen Yang, Wen Long Wang, Qi Wu Zhou, Bao Yu Zhao
Article
Ecology
Tianli Bao, Yunge Zhao, Xueqin Yang, Wei Ren, Shanshan Wang
JOURNAL OF ARID ENVIRONMENTS
(2019)
Article
Agronomy
Xueqin Yang, Mingxiang Xu, Yunge Zhao, Liqian Gao, Shanshan Wang
PLANT SOIL AND ENVIRONMENT
(2019)
Article
Agronomy
Tianli Bao, Liqian Gao, Shanshan Wang, Xueqin Yang, Wei Ren, Yunge Zhao
Article
Environmental Sciences
Bo Ma, Shanshan Wang, Christophe Mupenzi, Haoran Li, Jianye Ma, Zhanbin Li
Summary: Vegetation changes in the Upper White Nile River (UWNR) are relatively stable, but degradation is significant in some areas, particularly in agricultural land. The future trend analysis shows that vegetation in the UWNR will mainly degrade, with human activities being the main driving force.
Article
Soil Science
Shanshan Wang, Baoyuan Liu, Yunge Zhao, Liqian Gao, Bing Yin, Kai Yang, Jingyi Ji
Summary: The study found that the types of biocrust logarithmically increased with increasing plot sizes. Plot sizes larger than 0.25 m(2) supported mixed biocrusts of multiple patch types. The coverage of mixed biocrusts logarithmically decreased with increasing plot sizes, maintaining a constant value after reaching a critical plot size.
Article
Agronomy
D. M. Wang, Y. J. Zhang, S. S. Wang, D. W. Li
ALLELOPATHY JOURNAL
(2013)
Article
Agricultural Engineering
Jingmo Zhou, Shubin Wu, Ying Liu
Summary: Expenditure isolation of lignin and the understanding of its structural variations during different isolation processes are crucial for the high-value utilization of lignin. This study proposed a green deep eutectic solvent (DES) consisting of choline chloride, ethylene glycol, and 4-chlorobenzene sulfonic acid for rapid lignin separation from poplar. The structural variations of DES lignin and its relationship with alkali pre-extraction of hemicellulose were investigated. The results showed that alkali pretreatment enhanced the DES separation of lignin and promoted the cleavage of specific linkages, resulting in reduced molecular weight and thermal stability of isolated DES lignin. Moreover, DES lignin obtained from integrated utilization displayed higher purity and S/G ratio compared to lignin obtained from direct DES treatment.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Yuping Li, Ziyan Xie, Yun Huang, Jiangyi Zeng, Chao Yang, Ling Yuan, Ying Wang, Yongqing Li
Summary: In this study, the characteristic flavonoids (CFs) of three licorice species were identified through integrated metabolic and transcriptomic analysis. The key regulators of CF biosynthesis were also identified. These findings provide valuable information for understanding the biosynthesis of CFs and future breeding of Glycyrrhiza varieties.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Xianjie Pan, Zhaoyi Luo, Fanqi Liu, Quanqian Yi, Yanning Zeng
Summary: This study presents a novel strategy for fabricating fully bio-based epoxy vitrimers using peach gum and itaconic acid, which exhibit superior mechanical properties and thermostability. The materials were characterized and the self-healing and recycling capabilities were evaluated. The results demonstrate the potential of using these materials for sustainable industrial applications.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Mohsen Sabzi-Nojadeh, Mohammad Pouresmaeil, Mina Amani, Mehdi Younessi-Hamzekhanlu, Filippo Maggi
Summary: This study shows that inoculating Summer savory plants with endophytic fungus Trichoderma harzianum can improve plant growth and increase salt tolerance. The fungus enhances growth, restores chlorophyll and antioxidant levels, reduces harmful substances, and increases proline and soluble sugar levels, thereby increasing crop productivity in saline conditions.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Yu Liu, Lei Li, Aichen Zhao, Xiuming Song, Lulu Wei, Mengdi Fang, Chuchu Zheng, Xiaodong Zhu
Summary: This study investigates the impact of peppermint essential oil microcapsules on the unpleasant odor emissions from wax oil coated wood products. The results show that microcapsules can improve the time and stability of odor release.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Mesut Budak, Mirac Kilic, Hikmet Guenal, Ismail Velik, Mesut Sirri
Summary: This study assessed land suitability for rapeseed production using topography, climate, and soil data by analytical hierarchy process (AHP) and the Mamdani Fuzzy Inference System (MFIS). The study area covered land in the Diyarbakir province of southeastern Turkiye. The results indicated the proportions of different land suitability classes and showed the compatibility of AHP and MFIS methods in assessing suitability.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Rui Tian, Yue Liu, Chao Wang, Weikun Jiang, Srinivas Janaswamy, Guihua Yang, Xingxiang Ji, Gaojin Lyu
Summary: In this study, hollow and solid lignin nanoparticles were synthesized through self-assembly and their application in PVA nanocomposite films was investigated. The results showed that the presence of hollow lignin nanoparticles in the films resulted in a room-like network structure, while the solid lignin nanoparticles induced different structural changes. The inclusion of LNPs improved the mechanical properties of the films, and both types of LNPs exhibited good hydrophobicity.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Marcos Vinicius Silva de Andrade, Simone Ribeiro Lucho, Renato Delmondez de Castro, Paulo Roberto Ribeiro
Summary: Stevia rebaudiana Bertoni, commonly known as stevia, is a widely cultivated shrub with highly sweetening metabolites. It has gained significant interest in the food and beverage industries due to its extremely sweet taste and various health benefits. Researchers are currently focused on studying biotechnological strategies to enhance the biosynthesis of stevia plant metabolites for improved cultivation and production.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Eleonora Cintura, Paulina Faria, Luisa Molari, Luca Barbaresi, Dario D'Orazio, Lina Nunes
Summary: This study investigated the properties of Arundo donax as a building material and found that it has strong adaptability, high hygroscopicity, and unique sound absorption behavior. The mechanical tests also demonstrated the applicability of the Arundo donax-based composite. This opens up new possibilities for the further application of Arundo donax-based materials.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Stiina Kotiranta, Juha-Matti Pihlava, Titta Kotilainen, Pauliina Palonen
Summary: The effect of light spectra, particularly far-red and short wavelength radiation, on the growth and secondary metabolites of cannabis is significant. Altering the R:FR ratio can increase the concentration and yield of secondary metabolites, while short wavelength radiation does not significantly affect plant morphology and secondary metabolite concentrations.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Xuze Liu, Fangmin Liang, Jinyuan Cheng, Xuelian Zhou, Jia Wang, Guigan Fang, Kuizhong Shen, Xianzhi Meng, Chen Huang, Arthur J. Ragauskas
Summary: A novel Na2S-facilitated DES pretreatment method was proposed to fractionate moso bamboo, which achieved high lignin removal and preserved most cellulose and hemicellulose with excellent enzymatic digestibility.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Zechun Ren, Xinyuan Zhou, Kejiao Ding, Tong Ji, Hao Sun, Xiang Chi, Yunzhao Wei, Min Xu
Summary: This study prepared a thermal/magnetic/light-triggered multi-stimuli responsive shape memory polymer composite with excellent properties by adding magnetic nanoparticles into a polyurethane composite. The composite showed high shape recovery rate, fast response behavior, and suitability for 3D printing. Controllable external stimuli allowed for dynamic, remote, and precise control of 4D transformations. This work is significant for the design of smart materials and devices.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Yurany Camacho Ardila, Jaiver Efren Jaimes Figueroa, Maria Regina Wolf Maciel
Summary: The higher heating value (HHV) and elemental composition are important properties of biomass, and their prediction using proximate and ultimate analysis is accurate.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Xiaohan Chen, Xianke Wang, Lili Shang, Xinxin Ma, Changhua Fang, Benhua Fei, Huanrong Liu, Shuqin Zhang
Summary: This study focuses on the comprehensive characterization of the three-dimensional (3D) structure of bamboo parenchyma and the evaluation of its tensile and compressive properties, as well as the analysis of its failure mechanisms. The study found that the measured tensile strength and elastic modulus of the parenchyma tissue are 48.81 MPa and 706.48 MPa, respectively. Compression failure modes in parenchyma tissue encompass compression bending and cell fracture, shear failure of the middle lamella, and detachment and debonding of the cell wall.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Tianfeng Liu, Yuxin Liu, Yunlin Fu, Mengji Qiao, Penglian Wei, Zhigao Liu, Yingjian Li
Summary: This study explored the formation mechanism of agarwood induced by fungus and its potential application in high-quality and high-yielding agarwood production. The results showed that the transition layer played a critical role in the continuous accumulation of agarwood, and the parenchyma cells of the xylem rays and interxylary phloem were the main action site of fungus. The accumulation and distribution of chemical composition in different layers were also investigated. The study identified the drivers of specific compounds and provided a theoretical foundation for future agarwood production.
INDUSTRIAL CROPS AND PRODUCTS
(2024)