REDD2 expression in rat skeletal muscle correlates with nutrient-induced activation of mTORC1: responses to aging, immobilization, and remobilization

Molecular mechanisms of ageing and related diseases

(2014) Jun-Ping Liu   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Application of the [γ-32P] ATP kinase assay to study anabolic signaling in human skeletal muscle

(2014) Chris McGlory et al.   JOURNAL OF APPLIED PHYSIOLOGY

Chronic α-hydroxyisocaproic acid treatment improves muscle recovery after immobilization-induced atrophy

(2013) Charles H. Lang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Alterations in human muscle protein metabolism with aging: Protein and exercise as countermeasures to offset sarcopenia

(2013) Tyler A. Churchward-Venne et al.   BIOFACTORS

RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells

(2013) Bradley S. Gordon et al.   CELLULAR SIGNALLING

Mitochondrial dysfunction and sarcopenia of aging: From signaling pathways to clinical trials

(2013) Emanuele Marzetti et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation of muscle protein synthesis and the effects of catabolic states

(2013) Bradley S. Gordon et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb

(2012) Andrew R. Kelleher et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis: Figure 1

(2012) Valentina Iadevaia et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Contrarily to whey and high protein diets, dietary free leucine supplementation cannot reverse the lack of recovery of muscle mass after prolonged immobilization during ageing

(2012) Hugues Magne et al.   JOURNAL OF PHYSIOLOGY-LONDON

Delayed Recovery of Skeletal Muscle Mass following Hindlimb Immobilization in mTOR Heterozygous Mice

(2012) Susan M. Lang et al.   PLoS One

Aging Affects the Transcriptional Regulation of Human Skeletal Muscle Disuse Atrophy

(2012) Charlotte Suetta et al.   PLoS One

mTOR: on target for novel therapeutic strategies in the nervous system

(2012) Kenneth Maiese et al.   TRENDS IN MOLECULAR MEDICINE

β-Hydroxy-β-methylbutyrate reduces myonuclear apoptosis during recovery from hind limb suspension-induced muscle fiber atrophy in aged rats

(2011) Yanlei Hao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Blunting of adaptive responses to resistance exercise training in women over 75y

(2011) C.A. Greig et al.   EXPERIMENTAL GERONTOLOGY

Mammalian Target of Rapamycin Complex 1 Activation Is Required for the Stimulation of Human Skeletal Muscle Protein Synthesis by Essential Amino Acids

(2011) Jared M. Dickinson et al.   JOURNAL OF NUTRITION

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Dietary fish oil alleviates soleus atrophy during immobilization in association with Akt signaling to p70s6k and E3 ubiquitin ligases in rats

(2010) Jae-Sung You et al.   Applied Physiology Nutrition and Metabolism

Pharmacological Vasodilation Improves Insulin-Stimulated Muscle Protein Anabolism but Not Glucose Utilization in Older Adults

(2010) K. L. Timmerman et al.   DIABETES

Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway

(2010) Mikael Altun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Excess Leucine Intake Enhances Muscle Anabolic Signaling but Not Net Protein Anabolism in Young Men and Women

(2010) Erin L. Glynn et al.   JOURNAL OF NUTRITION

Blunting of insulin inhibition of proteolysis in legs of older subjects may contribute to age-related sarcopenia

(2009) Emilie A Wilkes et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch

(2009) Mitsunori Miyazaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Anabolic resistance: the effects of aging, sexual dimorphism, and immobilization on human muscle protein turnoverThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

(2009) Michael J. Rennie   Applied Physiology Nutrition and Metabolism

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

(2009) Valérie Risson et al.   JOURNAL OF CELL BIOLOGY

Elevated Corticosterone Associated with Food Deprivation Upregulates Expression in Rat Skeletal Muscle of the mTORC1 Repressor, REDD1

(2009) Nora K. McGhee et al.   JOURNAL OF NUTRITION

A Moderate Serving of High-Quality Protein Maximally Stimulates Skeletal Muscle Protein Synthesis in Young and Elderly Subjects

(2009) T. Brock Symons et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Age-Related Deficit in Load-Induced Skeletal Muscle Growth

(2009) D. T. Hwee et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Human Muscle Gene Expression following Resistance Exercise and Blood Flow Restriction

(2009) MICAH J. DRUMMOND et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women

(2009) Arkan Abadi et al.   PLoS One

ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression

(2008) Michael L. Whitney et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

(2008) C. Florian Bentzinger et al.   Cell Metabolism

Effect of unloading followed by reloading on expression of collagen and related growth factors in rat tendon and muscle

(2008) K. M. Heinemeier et al.   JOURNAL OF APPLIED PHYSIOLOGY

Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis

(2008) Micah J. Drummond et al.   JOURNAL OF APPLIED PHYSIOLOGY