CB1R antagonist increases hepatic insulin clearance in fat-fed dogs likely via upregulation of liver adiponectin receptors

Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity

(2014) Joseph Tam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hepatic insulin clearance is the primary determinant of insulin sensitivity in the normal dog

(2013) Marilyn Ader et al.   Obesity

CEACAM1 loss links inflammation to insulin resistance in obesity and non-alcoholic steatohepatitis (NASH)

(2013) Sonia M. Najjar et al.   Seminars in Immunopathology

CB1 antagonism restores hepatic insulin sensitivity without normalization of adiposity in diet-induced obese dogs

(2012) Stella P. Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hepatic Cannabinoid Receptor-1 Mediates Diet-Induced Insulin Resistance via Inhibition of Insulin Signaling and Clearance in Mice

(2012) Jie Liu et al.   GASTROENTEROLOGY

Glucagon and lipid interactions in the regulation of hepatic AMPK signaling and expression of PPARα and FGF21 transcripts in vivo

(2010) Eric D. Berglund et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors

(2010) John T. Heiker et al.   BIOLOGICAL CHEMISTRY

A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents

(2010) NL Cluny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

(2010) Joseph Tam et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C

(2010) Carmelo García-Monzón et al.   JOURNAL OF HEPATOLOGY

Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet

(2009) Mélissa Flamment et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Rimonabant prevents additional accumulation of visceral and subcutaneous fat during high-fat feeding in dogs

(2009) Joyce M. Richey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adiponectin is required to mediate rimonabant-induced improvement of insulin sensitivity but not body weight loss in diet-induced obese mice

(2009) Stéphanie Migrenne et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Depot-Specific Differences in Adipogenic Progenitor Abundance and Proliferative Response to High-Fat Diet

(2009) Aaron W.B. Joe et al.   STEM CELLS

Effect of Rimonabant on the High-Triglyceride/ Low–HDL-Cholesterol Dyslipidemia, Intraabdominal Adiposity, and Liver Fat

(2008) Jean-Pierre Després et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1: A Link Between Insulin and Lipid Metabolism

(2008) A. M. DeAngelis et al.   DIABETES

Improved mitochondrial function and increased life span after chronic melatonin treatment in senescent prone mice

(2008) María I. Rodríguez et al.   EXPERIMENTAL GERONTOLOGY

Increased Liver Fat, Impaired Insulin Clearance, and Hepatic and Adipose Tissue Insulin Resistance in Type 2 Diabetes

(2008) Anna Kotronen et al.   GASTROENTEROLOGY

Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury

(2008) Mingyan Zhou et al.   HEPATOLOGY

Animal models of NASH: Getting both pathology and metabolic context right

(2008) Claire Z Larter et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Toward a Global View of Alcohol, Tobacco, Cannabis, and Cocaine Use: Findings from the WHO World Mental Health Surveys

(2008) Louisa Degenhardt et al.   PLOS MEDICINE