Secreted protein acidic and rich in cysteine facilitates age-related cardiac inflammation and macrophage M1 polarization

Cardiac aging is initiated by matrix metalloproteinase-9-mediated endothelial dysfunction

(2014) Andriy Yabluchanskiy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanistic Relationship Between Membrane Type-1 Matrix Metalloproteinase and the Myocardial Response to Pressure Overload

(2014) Michael R. Zile et al.   Circulation-Heart Failure

Modulation of Circulating Macrophage Migration Inhibitory Factor in the Elderly

(2014) Christos Rammos et al.   Biomed Research International

Secreted Protein Acidic and Rich in Cysteine (SPARC) Exacerbates Colonic Inflammatory Symptoms in Dextran Sodium Sulphate-Induced Murine Colitis

(2013) Yoke-Leng Ng et al.   PLoS One

Elevated Plasma SPARC Levels Are Associated with Insulin Resistance, Dyslipidemia, and Inflammation in Gestational Diabetes Mellitus

(2013) Lu Xu et al.   PLoS One

Matrix metalloproteinase-9 deletion attenuates myocardial fibrosis and diastolic dysfunction in ageing mice

(2012) Ying Ann Chiao et al.   CARDIOVASCULAR RESEARCH

Matrix Metalloproteinase-28 Deletion Exacerbates Cardiac Dysfunction and Rupture After Myocardial Infarction in Mice by Inhibiting M2 Macrophage Activation

(2012) Yonggang Ma et al.   CIRCULATION RESEARCH

Normal ageing is associated with an increase in Th2 cells, MCP-1 (CCL1) and RANTES (CCL5), with differences in sCD40L and PDGF-AA between sexes

(2012) A. S. Mansfield et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Transgenic overexpression of matrix metalloproteinase-9 in macrophages attenuates the inflammatory response and improves left ventricular function post-myocardial infarction

(2012) Rogelio Zamilpa et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Age-related divergent remodeling of the cardiac extracellular matrix in heart failure: Collagen accumulation in the young and loss in the aged

(2012) Margaux A. Horn et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

SPARC Oppositely Regulates Inflammation and Fibrosis in Bleomycin-Induced Lung Damage

(2011) Sabina Sangaletti et al.   AMERICAN JOURNAL OF PATHOLOGY

Fractalkine: a novel cardiac chemokine?

(2011) S. E. Altin et al.   CARDIOVASCULAR RESEARCH

CXCR3 in T cell function

(2011) Joanna R. Groom et al.   EXPERIMENTAL CELL RESEARCH

Identification of a sequence in the matricellular protein SPARC that interacts with the scavenger receptor stabilin-1

(2011) Gail Workman et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Impact of cellular senescence signature on ageing research

(2010) Ewa Sikora et al.   AGEING RESEARCH REVIEWS

Macrophage Migration Inhibitory Factor Provides Cardioprotection During Ischemia/Reperfusion by Reducing Oxidative Stress

(2010) Kiyokazu Koga et al.   ANTIOXIDANTS & REDOX SIGNALING

Cardiac Inflammation Contributes to Changes in the Extracellular Matrix in Patients With Heart Failure and Normal Ejection Fraction

(2010) Dirk Westermann et al.   Circulation-Heart Failure

Age-dependent alterations in fibrillar collagen content and myocardial diastolic function: role of SPARC in post-synthetic procollagen processing

(2009) Amy D. Bradshaw et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mediators of neutrophil recruitment in human abdominal aortic aneurysms

(2009) Xavier Houard et al.   CARDIOVASCULAR RESEARCH

An Update of the Oxidation-Inflammation Theory of Aging: The Involvement of the Immune System in Oxi-Inflamm-Aging

(2009) Monica Fuente et al.   CURRENT PHARMACEUTICAL DESIGN

Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma

(2009) S. A. Arnold et al.   Disease Models & Mechanisms

Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion

(2009) Dake Qi et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of SPARC in extracellular matrix assembly

(2009) Amy D. Bradshaw   Journal of Cell Communication and Signaling

Molecular inflammation: Underpinnings of aging and age-related diseases

(2008) Hae Young Chung et al.   AGEING RESEARCH REVIEWS

Age-related cardiac muscle sarcopenia: Combining experimental and mathematical modeling to identify mechanisms

(2008) Jing Lin et al.   EXPERIMENTAL GERONTOLOGY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY