Low-density crystal packing of human protein kinase CK2 catalytic subunit in complex with resorufin or other ligands: a tool to study the unique hinge-region plasticity of the enzyme without packing bias

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Unprecedented Selectivity and Structural Determinants of a New Class of Protein Kinase CK2 Inhibitors in Clinical Trials for the Treatment of Cancer

(2011) Roberto Battistutta et al.   BIOCHEMISTRY

Structure of the Human Protein Kinase CK2 Catalytic Subunit CK2α′ and Interaction Thermodynamics with the Regulatory Subunit CK2β

(2011) Nils Bischoff et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural and functional analysis of the flexible regions of the catalytic α-subunit of protein kinase CK2

(2011) Elena Papinutto et al.   JOURNAL OF STRUCTURAL BIOLOGY

Enzymatic activity with an incomplete catalytic spine: insights from a comparative structural analysis of human CK2α and its paralogous isoform CK2α′

(2011) Nils Bischoff et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Structural and functional determinants of protein kinase CK2α: facts and open questions

(2011) Roberto Battistutta et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Emergence of protein kinase CK2 as a key target in cancer therapy

(2010) Janeen H. Trembley et al.   BIOFACTORS

CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy

(2010) A. Siddiqui-Jain et al.   CANCER RESEARCH

New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights

(2010) Miriam López-Ramos et al.   FASEB JOURNAL

Structural basis of CX-4945 binding to human protein kinase CK2

(2010) Andrew D. Ferguson et al.   FEBS LETTERS

Protein kinases: evolution of dynamic regulatory proteins

(2010) Susan S. Taylor et al.   TRENDS IN BIOCHEMICAL SCIENCES

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Resorufin: a lead for a new protein kinase CK2 inhibitor

(2009) Iben Skjøth Sandholt et al.   ANTI-CANCER DRUGS

Conformational plasticity of the catalytic subunit of protein kinase CK2 and its consequences for regulation and drug design

(2009) Karsten Niefind et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Protein Kinase CK2 in Health and Disease

(2009) K. Niefind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein Kinase CK2 in Health and Disease

(2009) R. Battistutta   CELLULAR AND MOLECULAR LIFE SCIENCES

First Inactive Conformation of CK2α, the Catalytic Subunit of Protein Kinase CK2

(2009) Jennifer Raaf et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2

(2009) WeiHong Zhou et al.   Science Bulletin

The CK2α/CK2β Interface of Human Protein Kinase CK2 Harbors a Binding Pocket for Small Molecules

(2008) Jennifer Raaf et al.   CHEMISTRY & BIOLOGY

Protein Kinase CK2 in Human Diseases

(2008) Barbara Guerra et al.   CURRENT MEDICINAL CHEMISTRY

The Catalytic Subunit of Human Protein Kinase CK2 Structurally Deviates from Its Maize Homologue in Complex with the Nucleotide Competitive Inhibitor Emodin

(2008) Jennifer Raaf et al.   JOURNAL OF MOLECULAR BIOLOGY

A helix scaffold for the assembly of active protein kinases

(2008) A. P. Kornev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrostatics-defying interaction between arginine termini as a thermodynamic driving force in protein-protein interaction

(2008) Deepa Pednekar et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS