Structural insights into the specific anti-HIV property of actinohivin: structure of its complex with the α(1–2)mannobiose moiety of gp120

Crystallographic study of the interaction of the anti-HIV lectin actinohivin with the α(1–2)mannobiose moiety of gp120 HMTG

(2012) Kaoru Suzuki et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Construct optimization for studying protein complexes: obtaining diffraction-quality crystals of the pseudosymmetric PSPC1–NONO heterodimer

(2011) Mihwa Lee et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The high mannose-type glycan binding lectin actinohivin: dimerization greatly improves anti-HIV activity

(2011) Atsushi Takahashi et al.   JOURNAL OF ANTIBIOTICS

Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy

(2011) Alex Sigal et al.   NATURE

Prevention of HIV-1 Infection with Early Antiretroviral Therapy

(2011) Myron S. Cohen et al.   NEW ENGLAND JOURNAL OF MEDICINE

HIV Treatment as Prevention

(2011) J. Cohen   SCIENCE

Actinohivin, a Broadly Neutralizing Prokaryotic Lectin, Inhibits HIV-1 Infection by Specifically Targeting High-Mannose-Type Glycans on the gp120 Envelope

(2010) B. Hoorelbeke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Actinohivin: specific amino acid residues essential for anti-HIV activity

(2010) Atsushi Takahashi et al.   JOURNAL OF ANTIBIOTICS

HIV-1 Neutralization Profile and Plant-Based Recombinant Expression of Actinohivin, an Env Glycan-Specific Lectin Devoid of T-Cell Mitogenic Activity

(2010) Nobuyuki Matoba et al.   PLoS One

Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity

(2010) Tinoush Moulaei et al.   STRUCTURE

Mechanism by which the lectin actinohivin blocks HIV infection of target cells

(2009) H. Tanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 Å resolution

(2008) Raimund Fromme et al.   PROTEIN SCIENCE