Lamin A/C deficiency reduces circulating tumor cell resistance to fluid shear stress

Surfactant functionalization induces robust, differential adhesion of tumor cells and blood cells to charged nanotube-coated biomaterials under flow

(2015) Michael J. Mitchell et al.   BIOMATERIALS

Immobilized surfactant-nanotube complexes support selectin-mediated capture of viable circulating tumor cells in the absence of capture antibodies

(2015) Michael J. Mitchell et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Fluid Shear Stress Increases Neutrophil Activation via Platelet-Activating Factor

(2014) Michael J. Mitchell et al.   BIOPHYSICAL JOURNAL

Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments

(2014) Patricia M. Davidson et al.   Cellular and Molecular Bioengineering

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

TRAIL-coated leukocytes that kill cancer cells in the circulation

(2014) M. J. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physical Biology in Cancer. 3. The role of cell glycocalyx in vascular transport of circulating tumor cells

(2013) Michael J. Mitchell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Differential drug responses of circulating tumor cells within patient blood

(2013) Andrew D. Hughes et al.   CANCER LETTERS

Nuclear Mechanics and Mechanotransduction in Health and Disease

(2013) Philipp Isermann et al.   CURRENT BIOLOGY

Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling

(2013) Monika Zwerger et al.   HUMAN MOLECULAR GENETICS

Nuclear Envelope Composition Determines the Ability of Neutrophil-type Cells to Passage through Micron-scale Constrictions

(2013) Amy C. Rowat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lamin A/C and emerin regulate MKL1–SRF activity by modulating actin dynamics

(2013) Chin Yee Ho et al.   NATURE

Fluid shear stress sensitizes cancer cells to receptor-mediated apoptosis via trimeric death receptors

(2013) Michael J Mitchell et al.   NEW JOURNAL OF PHYSICS

Stem Cell Enrichment with Selectin Receptors: Mimicking the pH Environment of Trauma

(2013) Thong Cao et al.   SENSORS

Broken nuclei – lamins, nuclear mechanics, and disease

(2013) Patricia M. Davidson et al.   TRENDS IN CELL BIOLOGY

Computational and Experimental Models of Cancer Cell Response to Fluid Shear Stress

(2013) Michael J. Mitchell et al.   Frontiers in Oncology

Shear-Induced Resistance to Neutrophil Activation via the Formyl Peptide Receptor

(2012) Michael J. Mitchell et al.   BIOPHYSICAL JOURNAL

Lamins at a glance

(2012) C. Y. Ho et al.   JOURNAL OF CELL SCIENCE

E-selectin liposomal and nanotube-targeted delivery of doxorubicin to circulating tumor cells

(2012) Michael J. Mitchell et al.   JOURNAL OF CONTROLLED RELEASE

Nanostructured Surfaces to Target and Kill Circulating Tumor Cells While Repelling Leukocytes

(2012) Michael J. Mitchell et al.   Journal of Nanomaterials

Resistance to Fluid Shear Stress Is a Conserved Biophysical Property of Malignant Cells

(2012) J. Matthew Barnes et al.   PLoS One

Cancer biology and the nuclear envelope: A convoluted relationship

(2012) Jose I. de las Heras et al.   SEMINARS IN CANCER BIOLOGY

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Nanobiotechnology for the capture and manipulation of circulating tumor cells

(2011) Andrew D. Hughes et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

The lamin protein family

(2011) Travis A Dittmer et al.   GENOME BIOLOGY

TAN lines

(2011) G.W. Gant Luxton et al.   Nucleus

Loss of A-type lamin expression compromises nuclear envelope integrity in breast cancer

(2011) Callinice D. Capo-chichi et al.   Chinese Journal of Cancer

MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity

(2010) Martina Weber et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lamins as cancer biomarkers

(2010) Clare R. Foster et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement

(2010) E. S. Folker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphoaspirin (MDC-43), a novel benzyl ester of aspirin, inhibits the growth of human cancer cell lines more potently than aspirin: a redox-dependent effect

(2009) W. Zhao et al.   CARCINOGENESIS

Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins

(2009) C. Ostlund et al.   JOURNAL OF CELL SCIENCE

Expression, purification and use of recombinant annexin V for the detection of apoptotic cells

(2009) Susan E Logue et al.   Nature Protocols

Lamin A/C Is a Risk Biomarker in Colorectal Cancer

(2008) Naomi D. Willis et al.   PLoS One