Roles of cADPR and NAADP in pancreatic cells

Cytosolic CD38 Protein Forms Intact Disulfides and Is Active in Elevating Intracellular Cyclic ADP-ribose

(2011) Yong Juan Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic Adenosine Diphosphate Ribose Activates Ryanodine Receptors, whereas NAADP Activates Two-pore Domain Channels

(2011) Oluseye A. Ogunbayo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Connexin-43 Hemichannels Mediate Cyclic ADP-ribose Generation and Its Ca2+-mobilizing Activity by NAD+/Cyclic ADP-ribose Transport

(2011) Eun-Kyung Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Photoaffinity Labeling of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Targets in Mammalian Cells

(2011) Yaping Lin-Moshier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Photoaffinity Labeling of High Affinity Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Binding Proteins in Sea Urchin Egg

(2011) Timothy F. Walseth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of CD38 with intracellular enzymatic activity: a possible explanation for the insulin release induced by intracellular cADPR

(2011) Yasuhiko Ohta et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cyclic ADP-ribose and NAADP: fraternal twin messengers for calcium signaling

(2011) Hon Cheung Lee   Science China-Life Sciences

Store-Operated Calcium Channels: New Perspectives on Mechanism and Function

(2011) R. S. Lewis   Cold Spring Harbor Perspectives in Biology

An emerging role for NAADP-mediated Ca2+signaling in the pancreatic β-cell

(2011) Abdelilah Arredouani et al.   Islets

Ca2+ release induced by cADP-ribose is mediated by FKBP12.6 proteins in mouse bladder smooth muscle

(2010) Ji Zheng et al.   CELL CALCIUM

Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal Trafficking

(2010) Margarida Ruas et al.   CURRENT BIOLOGY

Acute Insulin Signaling in Pancreatic Beta-Cells Is Mediated by Multiple Raf-1 Dependent Pathways

(2010) Emilyn U. Alejandro et al.   ENDOCRINOLOGY

Generation of Cyclic ADP-ribose and Nicotinic Acid Adenine Dinucleotide Phosphate by CD38 for Ca2+Signaling in Interleukin-8-treated Lymphokine-activated Killer Cells

(2010) So-Young Rah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ecto-enzyme CD38 Is a Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Synthase That Couples Receptor Activation to Ca2+Mobilization from Lysosomes in Pancreatic Acinar Cells

(2010) François Cosker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca2+Currents in Isolated Lysosomes

(2010) Michael Schieder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin receptor signaling for the proliferation of pancreatic β-cells: Involvement of Ca2+second messengers, IP3, NAADP and cADPR

(2010) Asif Iqbal Shawl et al.   Islets

Dissociation of FKBP12.6 from ryanodine receptor type 2 is regulated by cyclic ADP-ribose but not β-adrenergic stimulation in mouse cardiomyocytes

(2009) Xu Zhang et al.   CARDIOVASCULAR RESEARCH

Cyclic ADP-ribose links metabolism to multiple fission in the dinoflagellate Crypthecodinium cohnii

(2009) Connie M.C. Lam et al.   CELL CALCIUM

An Ancestral Deuterostome Family of Two-pore Channels Mediates Nicotinic Acid Adenine Dinucleotide Phosphate-dependent Calcium Release from Acidic Organelles

(2009) Eugen Brailoiu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Cyclizing NAD to Cyclic ADP-ribose by ADP-ribosyl Cyclase and CD38

(2009) Richard Graeff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Enzymatic Evolution from a Dedicated ADP-ribosyl Cyclase to a Multifunctional NAD Hydrolase

(2009) Qun Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

(2009) Eugen Brailoiu et al.   JOURNAL OF CELL BIOLOGY

NAADP mobilizes calcium from acidic organelles through two-pore channels

(2009) Peter J. Calcraft et al.   NATURE

Identification of a chemical probe for NAADP by virtual screening

(2009) Edmund Naylor et al.   Nature Chemical Biology

The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores

(2009) Xiangang Zong et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist

(2009) W. Dammermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor-mediated signal transduction pathways and the regulation of pancreatic acinar cell function

(2008) John A Williams   CURRENT OPINION IN GASTROENTEROLOGY

Generation of Nicotinic Acid Adenine Dinucleotide Phosphate and Cyclic ADP-Ribose by Glucagon-Like Peptide-1 Evokes Ca2+ Signal That Is Essential for Insulin Secretion in Mouse Pancreatic Islets

(2008) B.-J. Kim et al.   DIABETES

Pancreas islets in metabolic signaling - focus on the beta-cell

(2008) Jakob Suckale   Frontiers in Bioscience-Landmark

Abscisic Acid Is an Endogenous Stimulator of Insulin Release from Human Pancreatic Islets with Cyclic ADP Ribose as Second Messenger

(2008) Santina Bruzzone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD38 is constitutively expressed in the nucleus of human hematopoietic cells

(2008) M. Orciani et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

NAADP: A Universal Ca2+ Trigger

(2008) A. H. Guse et al.   Science Signaling