Article
Cell Biology
Mengjia Li, Penglei Jiang, Kai Cheng, Zehui Zhang, Shuyu Lan, Xiaoxia Li, Lirong Zhao, Yucheng Wang, Xiang Wang, Jing Chen, Tao Ji, Bingshe Han, Junfang Zhang
Summary: The enhancer elements at -34k are crucial for MYB expression, with transcription factor binding and epigenetic modifications playing key roles in this process.
CELL DEATH & DISEASE
(2021)
Article
Plant Sciences
Xiaojuan Yin, Yibing Zhang, Li Zhang, Baohua Wang, Yidi Zhao, Muhammad Irfan, Lijing Chen, Yulong Feng
Summary: The study revealed that LvMYB5 plays a promoting role in flower color formation in lilies, while LvMYB1 acts as an inhibitor. These findings provide a theoretical basis for improving flower color through genetic engineering and offer a new direction for further research on the mechanisms of flower color formation in lilies.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Rebecca Harris, Suzanne Randle, Heike Laman
Summary: Fbxo7 plays a key role in the differentiation and function of various blood cell types, neurons, oligodendrocytes, and spermatocytes. Transcription factors such as ELF4, Pax5, and c-Myb have been identified to regulate FBXO7 expression, with Pax5 binding to the FBXO7 promoter in pre-B cells and repressing Fbxo7 transcription in early pro-B cells.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2021)
Article
Plant Sciences
Junsub Lim, Chae Woo Lim, Sung Chul Lee
Summary: CaDIM1, a MYB transcription factor, acts as a positive regulator of drought stress response by modulating ABA-mediated gene expression and enhancing drought tolerance.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Huiting Xi, Yaru Zhu, Wenwen Sun, Nan Tang, Zhengqin Xu, Xiaohong Shang, Yansheng Zhang, Huabing Yan, Changfu Li
Summary: Pueraria lobata, a traditional Chinese herb, produces puerarin, an isoflavone C-glucoside with medicinal properties. This study found that puerarin biosynthesis occurs in the roots and stems of P. lobata. RNA-sequencing analysis identified several genes involved in puerarin biosynthesis.
Article
Agronomy
Yue Cao, Xufeng Fang, Shi Liu, Feishi Luan
Summary: Watermelon is an economically important crop with rich antioxidant carotenoids in its pulp. This study identified critical sequence variations in the promoter region of the ClPsy1 gene, which is the rate-limiting enzyme for carotenoid synthesis. Further analysis revealed a transcription factor (Cla97C10G196920) that positively regulates the expression of ClPsy1 and carotenoid synthesis.
Review
Plant Sciences
Francesca Cappellini, Alessandra Marinelli, Marta Toccaceli, Chiara Tonelli, Katia Petroni
Summary: Anthocyanins are important red, purple, and blue pigments in plants with health-promoting properties against chronic diseases. Understanding the biosynthetic pathway and regulatory mechanisms of anthocyanins has led to the production of enriched foods and highlighted their health benefits in combating diseases.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Chitra Bhatia, Subhash Reddy Gaddam, Ashutosh Pandey, Prabodh Kumar Trivedi
Summary: Flavonols, a type of protective compounds, are regulated by light and other environmental factors. MYB12 has been identified as a key gene in Arabidopsis that regulates flavonol accumulation in response to light.
Review
Biochemistry & Molecular Biology
Huiling Yan, Xiaona Pei, Heng Zhang, Xiang Li, Xinxin Zhang, Minghui Zhao, Vincent L. Chiang, Ronald Ross Sederoff, Xiyang Zhao
Summary: Anthocyanins play a crucial role in providing different visual effects to plants through various biosynthetic pathways, attracting pollinators and seed dispersers. MYB transcription factors are key regulators in anthocyanin biosynthesis, controlling the enrichment and sedimentation of anthocyanins. The study discusses the regulation of anthocyanin biosynthetic mechanisms by MYB-TFs and analyzes the role of the environment in controlling the anthocyanin biosynthesis network.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Declan J. Lafferty, Richard Espley, Cecilia H. Deng, Catrin S. Gunther, Blue Plunkett, Janice L. Turner, Laura Jaakola, Katja Karppinen, Andrew C. Allan, Nick W. Albert
Summary: Members of the Vaccinium genus, such as blueberry and bilberry, have different concentrations and localization of anthocyanins due to the expression of key regulatory genes MYBPA1.1 and MYBA1. Blueberry lacks VcMYBA1 expression, resulting in insufficient VcMYBPA1.1 for anthocyanin regulation, while bilberry expresses VmMYBA1 which up-regulates VmMYBPA1.1 for coordinated regulation of flavonoid biosynthesis genes and anthocyanin accumulation.
JOURNAL OF EXPERIMENTAL BOTANY
(2022)
Article
Biochemistry & Molecular Biology
Congcong Wang, Kunying Hao, Lixia Dong, Jingnan Wang, Linchun Zhao, Lijun Xu, Yin Xia, Qing Jiang, Jinzhong Qin
Summary: This study using CRISPR/Cas9 genome editing demonstrated that deficiency of Lin54 or Lin52 components of the cell cycle regulatory MuvB complex in ESCs leads to G2/M arrest, loss of pluripotency, and spontaneous differentiation, with activation of mesoendodermal lineage-specifying genes. Furthermore, abnormalities in Lin54-null ESCs were partially rescued by ectopic coexpression of genes encoding G2/M proteins Cyclin B1 and Cdk1. These findings provide new insights into how the MuvB complex determines cell fate through regulation of the cell cycle machinery.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2022)
Article
Biotechnology & Applied Microbiology
Songtao Jiu, Le Guan, Xiangpeng Leng, Kekun Zhang, Muhammad Salman Haider, Xiang Yu, Xudong Zhu, Ting Zheng, Mengqing Ge, Chen Wang, Haifeng Jia, Lingfei Shangguan, Caixi Zhang, Xiaoping Tang, Muhammad Abdullah, Hafiz Umer Javed, Jian Han, Zhigang Dong, Jinggui Fang
Summary: This study elucidates the roles of VvMYBA2r and VvMYBA2w alleles in grape skin coloration, with VvMYBA2r positively regulating anthocyanin biosynthesis while VvMYBA2w showing limited efficacy. Different MYB haplotypes and ploidy levels also influence the grape skin color.
PLANT BIOTECHNOLOGY JOURNAL
(2021)
Review
Cell Biology
Sara S. Procknow, Beth A. Kozel
Summary: Elastin provides elasticity to tissues such as the lung, blood vessels, and skin, but the mechanisms regulating its production are not fully understood. Studying the expression of the ELN gene may help intervene in rare diseases and potentially replace age-related losses by re-initiating elastin production.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Yanfei Liu, Kangxun Ma, Yingwei Qi, Guowen Lv, Xiaolin Ren, Zhande Liu, Fengwang Ma
Summary: This study reveals the involvement of an MYB-bHLH-WD40 complex and multiple regulators in the regulation of anthocyanin synthesis in kiwifruit, including a complex that directly targets anthocyanin synthetic genes and another complex that indirectly regulates anthocyanin accumulation signal amplification.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Review
Biotechnology & Applied Microbiology
Xiaohan Huang, Qiaoqiao Song, Shuqi Guo, Qiang Fei
Summary: This review summarizes several transcription regulation strategies applied in methylotrophs and discusses their applications and prospects.
BIORESOURCES AND BIOPROCESSING
(2022)
