Exacerbation of experimental autoimmune encephalomyelitis in ceramide synthase 6 knockout mice is associated with enhanced activation/migration of neutrophils

Regulation of ceramide synthase 6 in a spontaneous experimental autoimmune encephalomyelitis model is sex dependent

(2014) Max Eberle et al.   BIOCHEMICAL PHARMACOLOGY

PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis

(2013) Susanne Schiffmann et al.   BIOCHEMICAL PHARMACOLOGY

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

(2013) K. De Filippo et al.   BLOOD

Ceramide metabolism in mouse tissue

(2013) Susanne Schiffmann et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Inactivation of Ceramide Synthase 6 in Mice Results in an Altered Sphingolipid Metabolism and Behavioral Abnormalities

(2013) Philipp Ebel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipidN-acyl chain

(2013) Sandra N. Pinto et al.   JOURNAL OF LIPID RESEARCH

Myelin Repair Is Accelerated by Inactivating CXCR2 on Nonhematopoietic Cells

(2013) L. Liu et al.   JOURNAL OF NEUROSCIENCE

Altering the sphingolipid acyl chain composition prevents LPS/GLN-mediated hepatic failure in mice by disrupting TNFR1 internalization

(2013) M Ali et al.   Cell Death & Disease

Ceramide and Apoptosis: Exploring the Enigmatic Connections between Sphingolipid Metabolism and Programmed Cell Death

(2012) Thomas D. Mullen et al.   Anti-Cancer Agents in Medicinal Chemistry

Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes

(2012) Joo-Won Park et al.   HEPATOLOGY

Ceramide Synthase 6 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis

(2012) S. Schiffmann et al.   JOURNAL OF IMMUNOLOGY

Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain

(2012) F.-Xabier Contreras et al.   NATURE

The cyclooxygenase-2 pathway via the PGE2 EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination

(2011) Sara Palumbo et al.   JOURNAL OF NEUROCHEMISTRY

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Activation of ceramide synthase 6 by celecoxib leads to a selective induction of C16:0-ceramide

(2010) Susanne Schiffmann et al.   BIOCHEMICAL PHARMACOLOGY

The blood–brain barrier, chemokines and multiple sclerosis

(2010) David W. Holman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction

(2010) H. Nguyen-Jackson et al.   BLOOD

Developmentally Regulated Ceramide Synthase 6 Increases Mitochondrial Ca2+Loading Capacity and Promotes Apoptosis

(2010) Sergei A. Novgorodov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

(2010) Kyle J. Eash et al.   JOURNAL OF CLINICAL INVESTIGATION

The Role of the Ceramide Acyl Chain Length in Neurodegeneration: Involvement of Ceramide Synthases

(2010) Oshrit Ben-David et al.   NEUROMOLECULAR MEDICINE

Induction of reactive oxygen species in bovine neutrophils is CD11b, but not dectin-1-dependent

(2010) I. Conejeros et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Sphingolipids in inflammation: pathological implications and potential therapeutic targets

(2009) Graeme F. Nixon   BRITISH JOURNAL OF PHARMACOLOGY

Ceramide synthases and ceramide levels are increased in breast cancer tissue

(2009) Susanne Schiffmann et al.   CARCINOGENESIS

The Protein Kinase IKKɛ Regulates Energy Balance in Obese Mice

(2009) Shian-Huey Chiang et al.   CELL

Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis

(2009) N. Nath et al.   JOURNAL OF IMMUNOLOGY

Therapeutic targeting of chemokine signaling in Multiple Sclerosis

(2008) Isabell Hamann et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TNFα blockade in human diseases: An overview of efficacy and safety

(2007) Jan Lin et al.   CLINICAL IMMUNOLOGY