Journal
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
Volume 35, Issue 2, Pages 287-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2015.01.007
Keywords
Anaphylaxis; Venom; Insect sting; Hymenoptera; Immunotherapy; Diagnostic tests; Mastocytosis
Categories
Funding
- Siemens
- Genentech
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Anaphylaxis to insect stings has occurred in 3% of adults and can be fatal even on the first reaction. Large local reactions are more frequent but rarely dangerous. The chance of a systemic reaction to a sting is 5% to 10% in large local reactors and in children with mild (cutaneous) systemic reactions, and varies between 30% and 65% in adults with previous systemic reactions, depending on the severity of previous sting reactions. Baseline serum tryptase level is increased in many patients with sting anaphylaxis. Venom immunotherapy is 75% to 98% effective in preventing sting anaphylaxis.
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