Regulatory T cells in B-cell-deficient and wild-type mice differ functionally and in expression of cell surface markers

Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4+CD25+FoxP3+ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells

(2014) X. Chen et al.   JOURNAL OF IMMUNOLOGY

B Lymphocytes Promote Expansion of Regulatory T Cells in Oral Tolerance: Powerful Induction by Antigen Coupled to Cholera Toxin B Subunit

(2014) J.-B. Sun et al.   JOURNAL OF IMMUNOLOGY

Peripheral CD4+T-cell tolerance is induced in vivo by rare antigen-bearing B cells in follicular, marginal zone, and B-1 subsets

(2013) Susan E. Murray et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Modulation of Treg cells/T effector function by GITR signaling is context-dependent

(2013) Amal Ephrem et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transient depletion of CD4+ CD25+regulatory T cells results in multiple autoimmune diseases in wild-type and B-cell-deficient NOD mice

(2013) Jason S. Ellis et al.   IMMUNOLOGY

Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells

(2013) Wing-hong Kwan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reduced Effectiveness of CD4+Foxp3+ Regulatory T Cells in CD28-Deficient NOD.H-2h4 Mice Leads to Increased Severity of Spontaneous Autoimmune Thyroiditis

(2013) J. S. Ellis et al.   JOURNAL OF IMMUNOLOGY

Follicular B Cells in Thyroids of Mice with Spontaneous Autoimmune Thyroiditis Contribute to Disease Pathogenesis and Are Targets of Anti-CD20 Antibody Therapy

(2013) S.-H. Hong et al.   JOURNAL OF IMMUNOLOGY

IL-10-producing regulatory B cells (B10 cells) in autoimmune disease

(2013) Ioannis Kalampokis et al.   ARTHRITIS RESEARCH & THERAPY

Activation of CD4+Foxp3+regulatory T cells proceeds normally in the absence of B cells during EAE

(2012) Kai Hoehlig et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

An N-Terminal Mutation of the Foxp3 Transcription Factor Alleviates Arthritis but Exacerbates Diabetes

(2012) Jaime Darce et al.   IMMUNITY

Loss of Epigenetic Modification Driven by the Foxp3 Transcription Factor Leads to Regulatory T Cell Insufficiency

(2012) Matthew L. Bettini et al.   IMMUNITY

Transient depletion of B cells in young mice results in activation of regulatory T cells that inhibit development of autoimmune disease in adults

(2012) S. Yu et al.   INTERNATIONAL IMMUNOLOGY

A Novel IL-10-Independent Regulatory Role for B Cells in Suppressing Autoimmunity by Maintenance of Regulatory T Cells via GITR Ligand

(2012) A. Ray et al.   JOURNAL OF IMMUNOLOGY

The Dual Effects of B Cell Depletion on Antigen-Specific T Cells in BDC2.5NOD Mice

(2012) Y. Xiang et al.   JOURNAL OF IMMUNOLOGY

CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients

(2012) A. J. Rech et al.   Science Translational Medicine

The effect of regulatory T-cell depletion on the spectrum of organ-specific autoimmune diseases in nonobese diabetic mice at different ages

(2011) Mami Nakahara et al.   AUTOIMMUNITY

Targeting Regulatory T Cells in Cancer

(2011) W. L. Byrne et al.   CANCER RESEARCH

Loss of Intra-Islet CD20 Expression May Complicate Efficacy of B-Cell–Directed Type 1 Diabetes Therapies

(2011) David V. Serreze et al.   DIABETES

Induction of Autoimmune Thyroiditis by Depletion of CD4+CD25+Regulatory T Cells in Thyroiditis-Resistant IL-17, But Not Interferon-γ Receptor, Knockout Nonobese Diabetic-H2h4Mice

(2011) Ichiro Horie et al.   ENDOCRINOLOGY

TNFR2 on non-haematopoietic cells is required for Foxp3+Treg-cell function and disease suppression in EAE

(2011) Niki Tsakiri et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The phenotypic and functional consequences of tumour necrosis factor receptor type 2 expression on CD4+ FoxP3+ regulatory T cells

(2011) Xin Chen et al.   IMMUNOLOGY

Resolving the identity myth: Key markers of functional CD4+FoxP3+ regulatory T cells

(2011) Xin Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

CD8+ T Cells Induce Thyroid Epithelial Cell Hyperplasia and Fibrosis

(2011) S. Yu et al.   JOURNAL OF IMMUNOLOGY

Natural but Not Inducible Regulatory T Cells Require TNF-  Signaling for In Vivo Function

(2011) W. J. Housley et al.   JOURNAL OF IMMUNOLOGY

B Cell Depletion Enhances T Regulatory Cell Activity Essential in the Suppression of Arthritis

(2011) K. M. Hamel et al.   JOURNAL OF IMMUNOLOGY

Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points

(2011) K. K. Dietze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Depletion of Foxp3+ Regulatory T Cells Improves Effective Therapeutic Vaccination against Established Melanoma

(2010) K. Klages et al.   CANCER RESEARCH

Conditional Regulatory T-Cell Depletion Releases Adaptive Immunity Preventing Carcinogenesis and Suppressing Established Tumor Growth

(2010) M. W. L. Teng et al.   CANCER RESEARCH

Regulatory B cells in autoimmunity: developments and controversies

(2010) Claudia Mauri et al.   Nature Reviews Rheumatology

CD4+CD25+ T-Cells Control Autoimmunity in the Absence of B-Cells

(2009) E. Marino et al.   DIABETES

Control of Regulatory T Cell Lineage Commitment and Maintenance

(2009) Steven Z. Josefowicz et al.   IMMUNITY

How Punctual Ablation of Regulatory T Cells Unleashes an Autoimmune Lesion within the Pancreatic Islets

(2009) Markus Feuerer et al.   IMMUNITY

Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells

(2009) Hélène Bour-Jordan et al.   IMMUNOLOGICAL REVIEWS

TCR Repertoire and Foxp3 Expression Define Functionally Distinct Subsets of CD4+ Regulatory T Cells

(2009) M. Kuczma et al.   JOURNAL OF IMMUNOLOGY

Resting B cells expand a CD4+CD25+Foxp3+ Treg population via TGF-β3

(2008) Shivanee Shah et al.   EUROPEAN JOURNAL OF IMMUNOLOGY