Inhibition of indoleamine 2,3-dioxygenase activity enhances the anti-tumour effects of a Toll-like receptor 7 agonist in an established cancer model

Kynurenine production mediated by indoleamine 2,3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis

(2014) Hirofumi Ohtaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Induction of hepatitis B virus surface antigen-specific cytotoxic T lymphocytes can be up-regulated by the inhibition of indoleamine 2, 3-dioxygenase activity

(2014) Hiroyasu Ito et al.   IMMUNOLOGY

Role of TNF-  Produced by Nonantigen-Specific Cells in a Fulminant Hepatitis Mouse Model

(2014) H. Ito et al.   JOURNAL OF IMMUNOLOGY

Long-term survival after adoptive bone marrow T cell therapy of advanced metastasized breast cancer: follow-up analysis of a clinical pilot trial

(2013) Christoph Domschke et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Generation of Tumor Antigen-Specific T Cell Lines from Pediatric Patients with Acute Lymphoblastic Leukemia--Implications for Immunotherapy

(2013) G. Weber et al.   CLINICAL CANCER RESEARCH

Effective Anti-Neu-Initiated Antitumor Responses Require the Complex Role of CD4+ T Cells

(2013) E. D. Mortenson et al.   CLINICAL CANCER RESEARCH

Toll-like Receptor agonists and alpha-galactosylceramide synergistically enhance the production of interferon-gamma in murine splenocytes

(2013) Tatsuya Ando et al.   Scientific Reports

Antitumor T-cell responses contribute to the effects of dasatinib on c-KIT mutant murine mastocytoma and are potentiated by anti-OX40

(2012) Y. Yang et al.   BLOOD

One-step simple assay to determine antigen-specific cytotoxic activities by single-color flow cytometry

(2011) Yohko Nakagawa et al.   BIOMEDICAL RESEARCH-TOKYO

Identification of IDO-Positive and IDO-Negative Human Dendritic Cells after Activation by Various Proinflammatory Stimuli

(2011) D. Von Bubnoff et al.   JOURNAL OF IMMUNOLOGY

Treatment Failure of a TLR-7 Agonist Occurs Due to Self-Regulation of Acute Inflammation and Can Be Overcome by IL-10 Blockade

(2010) H. Lu et al.   JOURNAL OF IMMUNOLOGY

Induction of IDO-1 by Immunostimulatory DNA Limits Severity of Experimental Colitis

(2010) M. A. Ciorba et al.   JOURNAL OF IMMUNOLOGY

The Absence of IDO Upregulates Type I IFN Production, Resulting in Suppression of Viral Replication in the Retrovirus-Infected Mouse

(2010) M. Hoshi et al.   JOURNAL OF IMMUNOLOGY

Ability of IDO To Attenuate Liver Injury in  -Galactosylceramide-Induced Hepatitis Model

(2010) H. Ito et al.   JOURNAL OF IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Interaction between LPS-induced NO production and IDO activity in mouse peritoneal cells in the presence of activated Vα14 NKT cells

(2009) Hirofumi Ohtaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes

(2009) M. D. Sharma et al.   BLOOD

IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism

(2008) Stefan Löb et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Role of V 14+ NKT cells in the development of Hepatitis B virus-specific CTL: activation of V 14+ NKT cells promotes the breakage of CTL tolerance

(2008) H. Ito et al.   INTERNATIONAL IMMUNOLOGY

HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase–dependent mechanism

(2008) Olivier Manches et al.   JOURNAL OF CLINICAL INVESTIGATION

TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours

(2008) H Conroy et al.   ONCOGENE