NK cells: tuned by peptide?

ERAP1 Regulates Natural Killer Cell Function by Controlling the Engagement of Inhibitory Receptors

(2015) L. Cifaldi et al.   CANCER RESEARCH

A deep look at KIR–HLA in Amerindians: Comprehensive meta-analysis reveals limited diversity of KIR haplotypes

(2015) Danillo G. Augusto et al.   HUMAN IMMUNOLOGY

Relative Expression Levels of the HLA Class-I Proteins in Normal and HIV-Infected Cells

(2015) Richard Apps et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Identification and Characterization of Human Intrahepatic CD49a+NK Cells

(2015) Nicole Marquardt et al.   JOURNAL OF IMMUNOLOGY

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1

(2015) Geraldine M. O'Connor et al.   JOURNAL OF VIROLOGY

AKIR Bcentromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia

(2015) Annettee Nakimuli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired natural killer cell responses are associated with loss of the highly activated NKG2A+CD57+CD56dim subset in HIV-1 subtype D infection in Uganda

(2014) Prossy Naluyima et al.   AIDS

Peptide selectivity discriminates NK cells from KIR2DL2- and KIR2DL3-positive individuals

(2014) Sorcha Cassidy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Cellular Redox Environment Alters Antigen Presentation

(2014) Jonathan A. Trujillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-12–producing monocytes and HLA-E control HCMV-driven NKG2C+ NK cell expansion

(2014) Alexander Rölle et al.   JOURNAL OF CLINICAL INVESTIGATION

KIR2DL3+NKG2A− natural killer cells are associated with protection from productive hepatitis C virus infection in people who inject drugs

(2014) Christine Thoens et al.   JOURNAL OF HEPATOLOGY

Synergistic Polymorphism at Two Positions Distal to the Ligand-Binding Site Makes KIR2DL2 a Stronger Receptor for HLA-C Than KIR2DL3

(2014) A. K. Moesta et al.   JOURNAL OF IMMUNOLOGY

IL-12-Dependent Inducible Expression of the CD94/NKG2A Inhibitory Receptor Regulates CD94/NKG2C+ NK Cell Function

(2014) A. Saez-Borderias et al.   JOURNAL OF IMMUNOLOGY

A Single Amino Acid Change in Inhibitory Killer Cell Ig-like Receptor Results in Constitutive Receptor Self-Association and Phosphorylation

(2014) Santosh Kumar et al.   JOURNAL OF IMMUNOLOGY

Human NKG2E Is Expressed and Forms an Intracytoplasmic Complex with CD94 and DAP12

(2014) Gerasim A. Orbelyan et al.   JOURNAL OF IMMUNOLOGY

Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity

(2014) G. M. O'Connor et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: NKG2ChiCD57+ NK Cells Respond Specifically to Acute Infection with Cytomegalovirus and Not Epstein-Barr Virus

(2014) D. W. Hendricks et al.   JOURNAL OF IMMUNOLOGY

Translating DRiPs: MHC class I immunosurveillance of pathogens and tumors

(2014) L. C. Anton et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The nature and extent of contributions by defective ribosome products to the HLA peptidome

(2014) D. Bourdetsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11

(2014) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA Editing Facilitates Immune Elimination of HCMV Infected Cells

(2014) Daphna Nachmani et al.   PLoS Pathogens

Dimorphic HLA-B signal peptides differentially influence HLA-E- and natural killer cell-mediated cytolysis of HIV-1-infected target cells

(2013) A. M. Merino et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Yin-Yang of KIR3DL1/S1: Molecular Mechanisms and Cellular Function

(2013) Geraldine M. O'Connor et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Association of killer cell immunoglobulin-like receptor polymorphisms with chronic hepatitis C and responses to therapy in Brazil

(2013) Janaina Mota de Vasconcelos et al.   GENETICS AND MOLECULAR BIOLOGY

Innate immune responses in hepatitis C virus-exposed healthcare workers who do not develop acute infection

(2013) Jens Martin Werner et al.   HEPATOLOGY

Polymorphism in Human Cytomegalovirus UL40 Impacts on Recognition of Human Leukocyte Antigen-E (HLA-E) by Natural Killer Cells

(2013) Susan L. Heatley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Large Spectrum of HLA-C Recognition by Killer Ig-like Receptor (KIR)2DL2 and KIR2DL3 and Restricted C1 Specificity of KIR2DS2: Dominant Impact of KIR2DL2/KIR2DS2 on KIR2D NK Cell Repertoire Formation

(2013) G. David et al.   JOURNAL OF IMMUNOLOGY

A Peptide Antagonist Disrupts NK Cell Inhibitory Synapse Formation

(2013) G. Borhis et al.   JOURNAL OF IMMUNOLOGY

KIR, HLA, and IL28B Variant Predict Response to Antiviral Therapy in Genotype 1 Chronic Hepatitis C Patients in Japan

(2013) Yuichi Nozawa et al.   PLoS One

Synergistic inhibition of natural killer cells by the nonsignaling molecule CD94

(2013) K. S. Cheent et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence ofKIRgenes and their HLA ligands in susceptibility to dengue in a population from southern Brazil

(2013) L. M. Beltrame et al.   TISSUE ANTIGENS

Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

(2013) Paul J. Norman et al.   PLoS Genetics

Kinetics of Antigen Expression and Epitope Presentation during Virus Infection

(2013) Nathan P. Croft et al.   PLoS Pathogens

MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements

(2012) D. P. Granados et al.   BLOOD

Host Translation at the Nexus of Infection and Immunity

(2012) Ian Mohr et al.   Cell Host & Microbe

Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion

(2012) Dimitra Peppa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Degenerate Recognition of MHC Class I Molecules with Bw4 and Bw6 Motifs by a Killer Cell Ig-like Receptor 3DL Expressed by Macaque NK Cells

(2012) Sebastien M. Maloveste et al.   JOURNAL OF IMMUNOLOGY

Global Subcellular Characterization of Protein Degradation Using Quantitative Proteomics

(2012) Mark Larance et al.   MOLECULAR & CELLULAR PROTEOMICS

Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2

(2012) Margit H. Lampen et al.   MOLECULAR IMMUNOLOGY

Distinct distribution of killer-cell immunoglobulin-like receptor genes in the Mugil and Ilaita areas of Papua New Guinea

(2012) E. John et al.   TISSUE ANTIGENS

Natural killer cells in experimental and human leishmaniasis

(2012) Christian Bogdan   Frontiers in Cellular and Infection Microbiology

Origin and plasticity of MHC I-associated self peptides

(2011) Danielle de Verteuil et al.   AUTOIMMUNITY REVIEWS

CMV drives clonal expansion of NKG2C+NK cells expressing self-specific KIRs in chronic hepatitis patients

(2011) Vivien Béziat et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

KIR genes and their human leukocyte antigen ligands in the progression to cirrhosis in patients with chronic hepatitis C

(2011) Amanda Vansan Marangon et al.   HUMAN IMMUNOLOGY

CD94 Is Essential for NK Cell-Mediated Resistance to a Lethal Viral Disease

(2011) Min Fang et al.   IMMUNITY

HIV-1 adaptation to NK-cell-mediated immune pressure

(2011) Galit Alter et al.   NATURE

Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B

(2011) Julian P. Vivian et al.   NATURE

Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection

(2011) M. M. Dring et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contribution of a mutational bias in hepatitis C virus replication to the genetic barrier in the development of drug resistance

(2011) M. H. Powdrill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural killer cell responses during viral infections: flexibility and conditioning of innate immunity by experience

(2011) Silvia M Vidal et al.   Current Opinion in Virology

Unconventional Repertoire Profile Is Imprinted during Acute Chikungunya Infection for Natural Killer Cells Polarization toward Cytotoxicity

(2011) Caroline Petitdemange et al.   PLoS Pathogens

Analyses of HLA-C-specific KIR repertoires in donors with group A and B haplotypes suggest a ligand-instructed model of NK cell receptor acquisition

(2010) K. Schonberg et al.   BLOOD

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection

(2010) Nadia Wauquier et al.   IMMUNOGENETICS

Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2

(2010) Susan E. Hiby et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus

(2010) Niklas K. Björkström et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antagonizing inhibition gets NK cells going

(2010) S. Rajagopalan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action

(2010) A. Lev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptide antagonism as a mechanism for NK cell activation

(2010) L. Fadda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HLA class I molecules reflect an altered host proteome after influenza virus infection

(2009) Angela Wahl et al.   HUMAN IMMUNOLOGY

SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels

(2009) Ulrike Lorenz   IMMUNOLOGICAL REVIEWS

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C

(2009) Thorsten Graef et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fine characterization of intrahepatic NK cells expressing natural killer receptors in chronic hepatitis B and C

(2009) Paula Bonorino et al.   JOURNAL OF HEPATOLOGY

Effect of Killer Immunoglobulin-Like Receptors in the Response to Combined Treatment in Patients with Chronic Hepatitis C Virus Infection

(2009) J. R. Vidal-Castineira et al.   JOURNAL OF VIROLOGY

Adaptive immune features of natural killer cells

(2009) Joseph C. Sun et al.   NATURE

Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands

(2009) K. Gendzekhadze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

(2008) D. Pende et al.   BLOOD

MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

(2008) M. Yawata et al.   BLOOD

Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure

(2008) L Golden-Mason et al.   GUT

CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence

(2008) Emma J. Petrie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Influenza Virus Infection Augments NK Cell Inhibition through Reorganization of Major Histocompatibility Complex Class I Proteins

(2008) H. Achdout et al.   JOURNAL OF VIROLOGY

Interaction of NK inhibitory receptor genes with HLA-C and MHC class II alleles in Hepatitis C virus infection outcome

(2008) Viviana Romero et al.   MOLECULAR IMMUNOLOGY

Structural basis for NKG2A/CD94 recognition of HLA-E

(2008) B. K. Kaiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA