Article
Biochemical Research Methods
Serkan Sayin
Summary: In this study, a novel quinoline-functionalized calix [4] arene derivative (Quin-Calix) was successfully synthesized and characterized. The cation-binding property of Quin-Calix towards various metal ions was investigated, revealing a high affinity and selectivity, particularly for Cu2+ ion. The mechanism of quenching was elucidated using the Stern-Vohmer equation.
JOURNAL OF FLUORESCENCE
(2021)
Article
Chemistry, Physical
Zhengyan Zhao, Xiaolu Zhang, Xuedan Song, Ce Hao
Summary: Combining experimental and computational methods, this study investigated the recognition of Cu2+ ions by 9-hydroxyphenal-1-one carbon quantum dots (HPHN-CQDs), demonstrating their efficiency as a fluorescent probe with high selectivity and sensitivity. Analysis using density functional theory (DFT) and time-dependent density functional theory (TDDFT) revealed that Cu2+ affected the luminescence behavior of HPHN by altering its orbital distribution, leading to fluorescence quenching. The transfer of electrons from excited HPHN to Cu2+ hindered recombination of electron-hole pairs, explaining the decreased fluorescence rate constant of HPHN-Cu2+ compared to HPHN.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2021)
Article
Chemistry, Physical
Rongchuang Geng, Hanxiao Tang, Qiujuan Ma, Luping Liu, Weisheng Feng, Zhijuan Zhang
Summary: In this study, bimetallic Ag/Zn-ZIF-8 materials were developed for sensitive detection of Fe3+ and Cu2+. The synthesized materials showed high photoluminescence property and excellent fluorescence quenching responses to the target analytes, with detection limits comparable or better than reported sensors. The possible photoluminescence quenching mechanisms were studied in detail, with competitive absorption and resonance energy transfer identified as key factors.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Engineering, Environmental
Eun Hye Kwon, Hyejin An, Min Bum Park, Min Kim, Yeong Don Park
Summary: The research introduces a novel organic-inorganic hybrid gas sensor by combining zeolite and conjugated polymer, which enhances sensor's NO2 sensing performance while maintaining high responsivity and recovery rates. The study demonstrates that zeolite materials can protect the blend film from oxidation, ensuring the long-term stability of the sensor under ambient conditions.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Materials Science, Multidisciplinary
Tapas Goswami, Amarnath Bheemaraju, Aditya Kataria, Amit Nag, Kaja Sravani, Soni Mishra, Abhishek K. Mishra
Summary: A novel nanocluster PTCA/Capt-AgNC was designed in the research with significantly enhanced fluorescence, photostability and water solubility, showing great potential for highly efficient biosensors in the field of bio-sensing based on experimental and computational analyses.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Biology
Michael F. Priest, Elizabeth E. L. Lee, Francisco Bezanilla
Summary: The study revealed that the motion of charged residues R1 and R2 during activation involves rotation and tilted translation, with differences between the two. By observing the effect of amino acid mutations on a fluorescent positively charged derivative, the mechanism driving voltage sensor movement in response to membrane potential changes was elucidated.
Article
Chemistry, Physical
R. Kamal, M. Saif
Summary: In this study, Eu3+ doped Ba6Gd2W3O18 with nano-domain crystalline structure was successfully synthesized. The material, particularly BGWO: 0.10 mol Eu3+, exhibited strong red emission and long lifetime. It showed high selectivity and sensitivity towards copper ions compared to other metal ions. The sensitivity of copper ions was studied using the photoluminescence (PL) quenching method, and the optimized BGWO: 0.10 mol Eu3+ nanosensor demonstrated high recovery values in the detection of copper in drinking water and food samples.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2022)
Article
Biochemical Research Methods
Zengwei Yang, Yufei Yuan, Xiangfei Xu, Hongyu Guo, Fafu Yang
Summary: A novel AIE molecule (DHBB) with long-wavelength emission and good emission in aqueous media was prepared, which showed good sensing selectivity for Cu2+ and stable sensing ability at pH = 5-9. The recovery rate of cu2+ sensing in real samples was 96%. Moreover, DHBB exhibited good bio-imaging performance and sensing ability for Cu2+ in living cells.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Nanoscience & Nanotechnology
Rongjun Zhao, Zhezhe Wang, Xu Tian, Hui Shu, Yue Yang, Xuechun Xiao, Yude Wang
Summary: The study successfully prepared N-acetyl-L-cysteine modified CdS quantum dots for detecting metal ions in water systems. The fluorescence probe showed high sensitivity and selectivity for Cu2+ and exhibited an excellent linear relationship with the concentration of Cu2+ in a certain range.
Article
Chemistry, Inorganic & Nuclear
Yang Wang, Ya-Hui Su, Si-Min Gong, Jie-Ru Wang, Rui-Sha Zhou, Wei-Zhou Jiao, Jiang-Feng Song
Summary: In this study, five new coordination compounds with isomorphic frameworks were successfully synthesized and characterized. One of the compounds was found to be a multifunctional fluorescence probe.
JOURNAL OF SOLID STATE CHEMISTRY
(2022)
Article
Environmental Sciences
Yi Sun, Qingxiang Zhou, Xueying Sheng, Shuanying Li, Yayan Tong, Jinghan Guo, Boyao Zhou, Jingyi Zhao, Menghua Liu, Zhi Li, Yanhui Li, Tongxu Qu, Chunmao Chen
Summary: A fluorescent sensor was constructed using carbon quantum dots with high selectivity and sensitivity towards benzo[a]pyrene, showing great potential for practical application. The sensor exhibited excellent linearity and a low limit of detection, while also being simple, rapid, cost-effective, and stable.
Article
Polymer Science
Sultan Sacide Gelen, Tuvshinjargal Munkhbat, Zuale Rexhepi, Fatma Ozturk Kirbay, Hacer Azak, Dilek Odaci Demirkol
Summary: Conducting polymers can be used to prepare electrochemical and optical detection platforms for bioanalytical systems. In this study, a multifunctional monomer was synthesized for selective detection of H2O2, successfully immobilizing CAT on Poly(DTP-Trp) for target analyte detection. Surface characterization was done using SEM and EDX, confirming the presence of Poly(DTP-Trp)/CAT on ITO-PET surfaces.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Chemistry, Analytical
Evin Aysegul Simsir, Serkan Erdemir, Mustafa Tabakci, Begum Tabakci
Summary: A highly selective and sensitive MET detection method based on fluorescence quenching using a fluorescent calix[4]arene derivative has been reported. The probe showed great potential for practical applications, especially in pharmaceutical preparations, with fast and accurate detection of MET. The probe was successfully applied in pharmaceutical samples and as a paper-based sensor for MET detection.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Ranjithkumar Jakku, Steven H. Priver, Nedaossadat Mirzadeh, Ahmad E. Kandjani, Ylias Sabri, Stephen Kennedy, Ebtsam K. Alenezy, Salvy Russo, Igor Lyskov, Karen Wilson, Rajiv Trivedi, Suresh K. Bhargava
Summary: A new fluorescent organic molecular sensor based on bis(thienyl)imidazole was prepared and investigated for its sensing application towards metal ions in solution. Through the use of surface-enhanced Raman spectroscopy, successful detection of trace amounts of Cu(II) in aqueous media was achieved.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Inorganic & Nuclear
Ahmed Adel, Amr Abdelghany, Nabil Abdelmonem, Mona Elfiky, Osama Abuzalat
Summary: A sensitive fluorescence probe based on porous Lanthanum-1,4-benzenedicarboxylic frameworks (La-BDC) was developed for selective detection of 2-chloroethyl ethyl sulfide (2-CEES) at part per billion levels. The La-BDC particles were synthesized using the solvothermal method and characterized using FTIR spectroscopy, X-ray powder diffraction, scanning electron microscopy, UV-Vis spectrometry, and fluorescence spectroscopy. The LaBDC sensor showed a sensitive detection limit (LOD = 0.0521 nM, 0.0065 ppb) and a wide linear range of 25-400 ppb for 2-CEES, along with selectivity towards 2-CEES in the presence of dimethyl methyl phosphonate and hexane.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Plant Sciences
Li Wang, Hongtao Tu, Hui Hou, Zengqiang Zhou, Hongbo Yuan, Chaoxi Luo, Qinsheng Gu
Summary: Botryosphaeria dothidea was found to exhibit resistance to carbendazim, a devastating disease affecting apple crops. 19 isolates were found to have stable carbendazim resistance and a specific mutation in the beta-tubulin gene. A LAMP method was developed for rapid identification of this mutation, providing a valuable tool for monitoring and controlling resistance in apple crops.
Article
Engineering, Biomedical
Kaizheng Liu, Maury Wiendels, Hongbo Yuan, Changshun Ruan, Paul H. J. Kouwer
Summary: This article emphasizes the importance of three-dimensional hydrogel models in understanding and predicting cell behavior, highlighting the reciprocal interactions between cells and the extracellular matrix in regulating tissue functions. The structure, uses, advantages, and limitations of commonly used biopolymer networks, such as collagen, fibrin gels, and polyisocyanide gel, are discussed to provide guidance for tissue engineers and biophysicists in designing and utilizing these materials for 3D cell culture purposes.
BIOACTIVE MATERIALS
(2022)
Article
Agriculture, Multidisciplinary
Man Cheng, Hongbo Yuan, Qifan Wang, Zhenjiang Cai, Yueqin Liu, Yingjie Zhang
Summary: Animal behavior reflects health status and physiological stages. Automatic recognition of animal behavior improves breeding management and animal welfare. A deep learning model based on YOLO v5 network for sheep behavior recognition was proposed, showing that in structured scenarios with consistent training and test data characteristics, large amounts of training data are unnecessary.
COMPUTERS AND ELECTRONICS IN AGRICULTURE
(2022)
Article
Agriculture, Multidisciplinary
Qifan Wang, Man Cheng, Shuo Huang, Zhenjiang Cai, Jinlin Zhang, Hongbo Yuan
Summary: A convolution neural network model, YOLO-CBAM, is constructed in this paper for the detection of Solanum rostratum Dunal seedlings. High-resolution images are sliced using the overlap rate to construct datasets, and multiscale training methods are used to improve model performance. Comparison tests show that the proposed model outperforms the baseline model YOLO v5 in terms of precision and recall. Field trials demonstrate that the deployed model achieves high precision and recall for real-time recognition.
COMPUTERS AND ELECTRONICS IN AGRICULTURE
(2022)
Review
Public, Environmental & Occupational Health
Richard Wyss, Chen Yanover, Tal El-Hay, Dimitri Bennett, Robert W. Platt, Andrew R. Zullo, Grammati Sari, Xuerong Wen, Yizhou Ye, Hongbo Yuan, Mugdha Gokhale, Elisabetta Patorno, Kueiyu Joshua Lin
Summary: This paper surveys current approaches and recent advancements for high-dimensional proxy confounder adjustment in healthcare database studies, focusing on feature generation, covariate prioritization, selection, and adjustment, as well as diagnostic assessment. While there is a large literature on methods for high-dimensional confounder prioritization/selection, there is relatively little written on best practices for feature generation and diagnostic assessment, indicating particular limitations and challenges in these areas. Machine-learning algorithms are showing promise in supplementing investigator-specified variables to improve confounding control in pharmacoepidemiologic studies, but further research is needed on best practices for feature generation and diagnostic assessment in this context.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2022)
Article
Microbiology
Hongbo Yuan, Mengjia Yuan, Bingke Shi, Zhuoni Wang, Tianxiang Huang, Genhong Qin, Hui Hou, Li Wang, Hongtao Tu
Summary: This study revealed that the Paenibacillus polymyxa strain Nl4 has strong biocontrol efficacy against Valsa pyri, the causative agent of pear Valsa canker. Strain Nl4 exhibited inhibitory effects on the mycelial growth of V. pyri and caused hyphal malformation. Moreover, the culture filtrate of strain Nl4 showed protease, cellulase, and beta-1, 3-glucanase activity, which effectively suppressed the mycelial growth of V. pyri. Furthermore, strain Nl4 promoted plant growth and protected against pear Valsa canker symptoms. Transcriptomic analyses revealed that strain Nl4 regulated membrane- and energy metabolism-related genes in V. pyri, contributing to its biocontrol effects.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Energy & Fuels
Yanhong Luo, Hongbo Yuan, Xinying Wang, Ye Li, Jiangping Jing, Tao Da
Summary: This paper investigates the problem of energy planning in energy network and proposes an optimal scheduling strategy and a distributed cooperative control method. The proposed approach considers thermal inertia and renewable energy in the energy scheduling model, leading to economical and environmentally friendly operations in micro-energy networks. A real-time control using Linear Quadratic Gaussian (LQG) is used to ensure stable operation, and a dynamic stratification strategy is designed to optimize resource usage.
Review
Agriculture, Multidisciplinary
Zhenjiang Cai, Jialiang Cui, Hongbo Yuan, Man Cheng
Summary: Animal body temperature is closely related to its metabolism and life activities, reflecting the physiological and health status of animals. Infrared thermography (IRT) as a non-invasive measurement technology has been gradually applied in animal temperature measurement, allowing in-depth analysis of animal health and understanding of physiological changes. This paper summarized the research achievements of IRT in animal temperature detection and discussed its application cases, problems, and future development.
COMPUTERS AND ELECTRONICS IN AGRICULTURE
(2023)
Article
Polymer Science
Zhiyuan Si, Xinhai Zhao, Xinbo Ren, Chao Zheng, Hongbo Yuan, Ji Liu, Libin Song
Summary: In order to address the low transverse tensile strength issue of triaxial geogrid, a performance-optimized multi-axial geogrid (POMG) capable of withstanding larger transverse loads was designed. The forming equipment and process of POMG were designed, and through formability and mechanical property tests, POMG with good formability and mechanical properties, especially the one with circular and semicircular holes, achieved the highest average tensile strength exceeding 16 KN/m. Numerical simulation further validated the feasibility of the process and provided guidance on shape distribution and stress-strain behavior of POMG during the forming process.
Article
Microbiology
Hongbo Yuan, Mengjia Yuan, Bingke Shi, Zhuoni Wang, Tianxiang Huang, Jiahong Zhu, Hui Hou, Li Wang, Hongtao Tu
Summary: Apple ring rot, caused by Botryosphaeria dothidea, is a common postharvest disease of apple. This study investigated the biocontrol activity and mechanism of Bacillus halotolerans strain Pl7 against B. dothidea. Results showed that strain Pl7 exhibited strong inhibitory activity against B. dothidea and its culture filtrate possessed antifungal activity. Further analysis revealed that the culture filtrate of strain Pl7 could increase cell membrane permeabilization of B. dothidea. In apple fruit, strain Pl7 suppressed ring rot and showed the ability to colonize and thrive in fruit wounds. Transcriptome studies indicated that strain Pl7 mainly affected genes involved in plant secondary metabolite biosynthesis and plant-pathogen interaction. Overall, B. halotolerans strain Pl7 shows promise as a biocontrol agent against apple postharvest decay.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biochemical Research Methods
Yadong Liu, Hongbo Yuan, Xin Zhao, Caihu Fan, Man Cheng
Summary: The study presents a reconstruction method based on dual RGB-D cameras for quickly and accurately establishing a 3D model of the peanut plant. The method is 2.54 times faster than the widely used ICP algorithm with approximate accuracy. It offers a potential tool for improving traits and agronomic qualities of plants.
Article
Multidisciplinary Sciences
Hongbo Yuan, Kaizheng Liu, Mar Condor, Jorge Barrasa-Fano, Boris Louis, Johannes Vandaele, Paula de Almeida, Quinten Coucke, Wen Chen, Egbert Oosterwijk, Chengfen Xing, Hans Van Oosterwyck, Paul H. J. Kouwer, Susana Rocha
Summary: Cells sense external forces from the extracellular matrix (ECM) and generate contractile forces to stiffen and remodel the matrix. However, the underlying mechanisms of this bidirectional mechanical exchange are still poorly understood. This study uses a synthetic hydrogel based on polyisocyanide (PIC) polymers to investigate cell-matrix interactions and demonstrates the potential of PIC gels in studying mechanobiology and designing materials.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Review
Anesthesiology
Xianghong Lian, Yunzhu Lin, Ting Luo, Yang Jing, Hongbo Yuan, Yixin Guo
Summary: This study aimed to assess the efficacy and safety of esketamine as an adjunct to propofol for sedation during endoscopic procedures in patients. The results showed that the administration of esketamine reduced the recovery time compared to normal saline and required a lower propofol dosage. However, caution should be exercised due to the possibility of visual disturbance associated with esketamine use.
BMC ANESTHESIOLOGY
(2023)
Review
Medicine, General & Internal
Grammati Sarri, Elisabetta Patorno, Hongbo Yuan, Jianfei (Jeff) Guo, Dimitri Bennett, Xuerong Wen, Andrew R. Zullo, Joan Largent, Mary Panaccio, Mugdha Gokhale, Daniela Claudia Moga, M. Sanni Ali, Thomas P. A. Debray
Summary: This study developed a guidance using a mixed methods approach to direct researchers and healthcare decision-makers on when and how to combine evidence from non-randomised studies (NRS) and randomised controlled trials (RCTs) to enhance transparency and confidence. The framework consists of seven steps and offers recommendations on statistical approaches based on different healthcare decision-making scenarios.
BMJ EVIDENCE-BASED MEDICINE
(2022)
Article
Plant Sciences
Hongbo Yuan, Hui Hou, Zengqiang Zhou, Hongtao Tu, Li Wang
Summary: In this study, a simple LAMP approach was developed to rapidly detect the E198A mutation in apple bitter rot-causing C. gloeosporioides isolates. The optimized LAMP protocol allowed for the genotype determination of a given isolate within 60 minutes of incubation at 63 degrees C using four specific primers. The results of the reaction could be visually interpreted based on a fluorescent yellow-green color change and were further confirmed via gel electrophoresis. Importantly, this LAMP assay was capable of rapidly and reliably detecting apples infected with carbendazim-resistant isolates harboring the E198A mutation.
HORTICULTURAL PLANT JOURNAL
(2022)