Article
Chemistry, Multidisciplinary
Ikuya Matsumoto, Ryo Sekiya, Takeharu Haino
Summary: By decorating nanographenes with alkyl chains and controlling concentration, solvent polarity, temperature, and sonication, it is possible to achieve self-assembly and formation of stacked structures. Optical measurements and AFM images confirm the presence of stacked structures, while molecular mechanics calculations model the interactions within the aggregates. The nanographenes exhibit concentration-dependent morphologies, forming stacked structures at low concentrations and polymer-like network structures at higher concentrations on mica.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Polymer Science
Alexandra Croitoriu, Loredana Elena Nita, Alina Gabriela Rusu, Alina Ghilan, Maria Bercea, Aurica P. Chiriac
Summary: This study focuses on the preparation of a bionic hydrogel stabilized with a physiologically occurring, bifunctional biomolecule, L-lysine, co-assembled with other amino acids or peptides. The co-assembled supramolecular structure shows good rheological characteristics and has the potential to support tissue repair.
Article
Chemistry, Multidisciplinary
Mitsuaki Yamauchi, Seiya Yamamoto, Sadahiro Masuo
Summary: The study demonstrates a novel supramolecular coassembly system that forms highly ordered QD arrangement structures via self-assembly, enabling photocontrollable photoluminescence properties. The assembled system undergoes structural changes under light, but recovers its original structure and properties over time.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Mikiko Vazquez-Nakagawa, Laura Rodriguez-Perez, Nazario Martin, M. Angeles Herranz
Summary: This study describes a method for preparing new chiral graphene quantum dots through chemical functionalization, and examines their supramolecular assembly using microscopy. Fluorescence studies show that the fibers stem from the pi-pi stacking of pyrenes and GQDs, along with the hydrogen bonding interactions of the amide groups.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Kil Ho Lee, Megan Ireland, Brandon L. Miller, Barbara E. Wyslouzil, Jessica O. Winter
Summary: This paper investigates whether electrospray via interfacial instability self-assembly method can produce high-quality nanocomposites made of block co-polymers and organic nanoparticles. The findings show that surfactant-free approaches may increase encapsulation efficiency, product uniformity, and simplify downstream product purification processes.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Zheng Xing, Kaituo Dong, Nick Pavlopoulos, Yuexing Chen, Lilac Amirav
Summary: The study reports on a unique irradiation-triggered self-assembly and recrystallization phenomenon of crystalline carbon nitride quantum dots. Unlike conventional self-assembly of nanocrystals into ordered superstructures, this photoinduced self-assembly resembles a click reaction process of macromolecules, initiated by activated functional groups along the perimeters.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Chemistry, Physical
Qun Hao, Hongyu Lv, Haifei Ma, Xin Tang, Menglu Chen
Summary: Quantum dot materials, as zero-dimensional materials, have unique photophysical properties and potential applications in encryption, display, solar cells, and biomedical fields. However, their reliability and utility are greatly limited by chemical instability and low carrier transport efficiency due to the large surface to volume ratio. In this review, the self-assembly methods for quantum dots are discussed, analyzing their advantages and disadvantages. Furthermore, the challenges and improvements in the self-assembly method of quantum dots are prospectively discussed.
Article
Chemistry, Multidisciplinary
Madison Monahan, Micaela Homer, Shuai Zhang, Renyu Zheng, Chun-Long Chen, James De Yoreo, Brandi M. Cossairt
Summary: Self-assembled organic nanomaterials and inorganic nanoparticles can be combined to form hybrid structures. The assembly pathways and structural outcomes in these hybrid systems can be controlled by changing the solubility and size of the components. Quantum dots (QDs) and reversibly binding peptoids were used as the components in this study. In aqueous conditions, QDs stabilized certain morphologies of peptoid intermediates and generated multilayers of small peptoid sheets linked by QDs. In organic solvents, the assembly was facilitated or inhibited by the relative hydrophobicity of the QD surface ligands. Increasing the size of the QDs led to large hybrid sheets with highly ordered square-packed QDs. Additionally, binary hybrid lattices could be created by integrating smaller QD species. These findings provide design principles for controlling the structure and structural evolution of hybrid peptoid-QD assemblies.
Article
Chemistry, Multidisciplinary
Yonghong Song, Yueqiang Zhu, Kun Jiang, Xingyu Liu, Liang Dong, Dongdong Li, Sheng Chen, Hanye Xing, Xu Yan, Yang Lu, Xianzhu Yang, Junxia Wang, Yunjun Xu
Summary: Multifunctional magnet-fluorescent nanocomposites have wide applications in biomedical field. In this study, highly ferrimagnetic magnetic nanoparticles and ZnS/InP quantum dots were encapsulated in an amphiphilic block copolymer to obtain ferrimagnetic fluorescent micelles (FMFM) with uniform diameter and long-term stability. The FMFM showed excellent magnetic heating effect and magnetic resonance imaging capability, achieving improved magnetic hyperthermia therapy efficacy both in vitro and in vivo.
Article
Chemistry, Multidisciplinary
Chang Liu, Qing Li, Haopeng Wang, Gefei Wang, Haixia Shen
Summary: This work presents a self-healing assembly method for preparing various fluorescent quantum dots (QDs)-loaded gels. The as-prepared gels exhibit pH sensitivity, satisfactory mechanical properties, and excellent self-healing properties. The integration of QDs with gels enables the fabrication of fluorescent composites, which show potential applications in LED devices. Additionally, the self-healing assembly method using QDs-loaded gels as building blocks allows for the construction of complex structures with different fluorescence, which can be used for sensing and encoding purposes.
Article
Physics, Multidisciplinary
Julliany Louise Silva Hurbano Carvalho, Gustavo Fernandes Galli, Lucas Natalio Chavero, Lara Fernandes dos Santos
Summary: This study aimed to produce and study the morphology and optical properties of self-assembled structures based on carbon quantum dots. The carbon quantum dots were obtained by electrochemical exfoliation of a graphite electrode, and self-assembled structures were formed using the induced evaporation method. The study found that changes in temperature and solution volume significantly affected the characteristics of the self-assembled structures.
Article
Chemistry, Multidisciplinary
Sudipta Mondal, Pavel Rehak, Nandita Ghosh, Petr Kral, Ehud Gazit
Summary: This study demonstrates the formation of high persistence length one-dimensional arrays templated by self-assembling peptide fibers with asymmetrically distributed charged surfaces. The asymmetric nature of the peptide fibers allows charge-dependent deposition of nanoparticles, resulting in the formation of 1D arrays with higher persistence lengths.
Article
Chemistry, Applied
Yucun Liu, Yuan Wang, Lei Chen, Guangbo Che
Summary: Selective detection of nitroaromatics is still a major concern in national security and environmental protection. A new low molecular weight gelator based on the diphenyl imidazole group has been designed and characterized, and it can form stable organogels in DMSO and n-butanol solvents. Furthermore, this gelator works as a selective chemosensor for picric acid in solution and gel states with a fluorescence quenching mechanism.
Article
Chemistry, Multidisciplinary
Mona Atabakhshi-Kashi, Monica Carril, Hossein Mahdavi, Wolfgang J. Parak, Carolina Carrillo-Carrion, Khosro Khajeh
Summary: The successful conjugation of antibodies onto a fluorescent NP assembly demonstrated that the NP assembly retained the targeting ability of the antibodies in cellular uptake, while also preserving its intrinsic properties such as fluorescence.
Article
Multidisciplinary Sciences
Qing Zhang, Ruoyu Wang, Bowen Feng, Xiaoxia Zhong, Kostya (Ken) Ostrikov
Summary: The research successfully prepared Carbon Dots with high color purity fluorescence emission through amino protonation treatment, changing the molecular state of Carbon Dots and triggering red fluorescence emission, providing a new way for predicting and controlling the photoluminescence properties of Carbon Dots.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Myriam Roy, Veronika Berezhnaia, Marco Villa, Nicolas Vanthuyne, Michel Giorgi, Jean-Valere Naubron, Salome Poyer, Valerie Monnier, Laurence Charles, Yannick Carissan, Denis Hagebaum-Reignier, Jean Rodriguez, Marc Gingras, Yoann Coquerel
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2020)
Article
Biochemistry & Molecular Biology
Punit Saraon, Jamie Snider, Yannis Kalaidzidis, Leanne E. Wybenga-Groot, Konstantin Weiss, Ankit Rai, Nikolina Radulovich, Luka Drecun, Nika Vuckovic, Adriana Vucetic, Victoria Wong, Brigitte Theriault, Nhu-An Pham, Jin H. Park, Alessandro Datti, Jenny Wang, Shivanthy Pathmanathan, Farzaneh Aboualizadeh, Anna Lyakisheva, Zhong Yao, Yuhui Wang, Babu Joseph, Ahmed Aman, Michael F. Moran, Michael Prakesch, Gennady Poda, Richard Marcellus, David Uehling, Miroslav Samarzija, Marko Jakopovic, Ming-Sound Tsao, Frances A. Shepherd, Adrian Sacher, Natasha Leighl, Anna Akhmanova, Rima Al-awar, Marino Zerial, Igor Stagljar
NATURE CHEMICAL BIOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Nardin Nano, Francisca Ugwu, Thiago Seraphim, Tangzhi Li, Gina Azer, Methvin Isaac, Michael Prakesch, Leandro R. S. Barbosa, Carlos H. Ramos, Alessandro Datti, Walid A. Houry
Article
Biochemistry & Molecular Biology
Ganna Posternak, Xiaojing Tang, Pierre Maisonneuve, Ting Jin, Hugo Lavoie, Salima Daou, Stephen Orlicky, Theo Goullet de Rugy, Lauren Caldwell, Kin Chan, Ahmed Aman, Michael Prakesch, Gennady Poda, Pavel Mader, Cassandra Wong, Stefan Maier, Julia Kitaygorodsky, Brett Larsen, Karen Colwill, Zhe Yin, Derek F. Ceccarelli, Robert A. Batey, Mikko Taipale, Igor Kurinov, David Uehling, Jeff Wrana, Daniel Durocher, Anne-Claude Gingras, Rima Al-Awar, Marc Therrien, Frank Sicheri
NATURE CHEMICAL BIOLOGY
(2020)
Article
Chemistry, Multidisciplinary
Peng Liu, Xiaoze Bao, Jean-Valere Naubron, Sara Chentouf, Stephane Humbel, Nicolas Vanthuyne, Marion Jean, Laurent Giordano, Jean Rodriguez, Damien Bonne
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2020)
Article
Multidisciplinary Sciences
Jiangkun Ouyang, Anne Swartjes, Marc Geerts, Pieter J. Gilissen, Danni Wang, Paula C. P. Teeuwen, Paul Tinnemans, Nicolas Vanthuyne, Sara Chentouf, Floris P. J. T. Rutjes, Jean-Valere Naubron, Jeanne Crassous, Johannes A. A. W. Elemans, Roeland J. M. Nolte
NATURE COMMUNICATIONS
(2020)
Article
Chemistry, Organic
Isita Banerjee, Keshab Ch Ghosh, Emmanuel Oheix, Marion Jean, Jean-Valere Naubron, Marius Reglier, Olga Iranzo, Surajit Sinha
Summary: 3,4-Dimercaptophenylalanines and 2,3-dimercaptophenylalanines have been successfully synthesized for the first time, with the absolute configuration determined by X-ray crystallography and VCD/DFT measurements. Optically pure L-Fmoc-protected 3,4-analogue was incorporated into a decapeptide using standard solid-phase peptide synthesis, providing new molecular tools for research in catalysis, diagnostics, and nanotechnology.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Plant Sciences
Isabelle Pouny, Christophe Long, Muriel Batut, Yannick Aussagues, Naubron Jean Valere, Gaston Achoundong, Bruno David, Catherine Lavaud, Georges Massiot
Summary: Five new quinolizidine alkaloids, named cylicomorphins A-E, were isolated from the leaves of Cylicomorpha solmstii. They are all ester derivatives of the same basic quinolizidine skeleton and exhibit cytotoxicity against HCT-116 cell line.
JOURNAL OF NATURAL PRODUCTS
(2021)
Article
Chemistry, Medicinal
David E. Uehling, Babu Joseph, Kim Chan Chung, Andrew X. Zhang, Spencer Ler, Michael A. Prakesch, Gennady Poda, Julie Grouleff, Ahmed Aman, Taira Kiyota, Chungyee Leung-Hagesteijn, John David Konda, Richard Marcellus, Carly Griffin, Ratheesh Subramaniam, Ayome Abibi, Craig A. Strathdee, Methvin B. Isaac, Rima Al-Awar, Rodger E. Tiedemann
Summary: The study reveals that targeting GRK6 with small molecule inhibitors is a promising therapeutic approach for multiple myeloma, and identifies a potential novel compound, 18, with potent efficacy.
JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Enzo Olivieri, Guilhem Quintard, Jean-Valere Naubron, Adrien Quintard
Summary: The study introduces a fueling method using trichloroacetic acid to create dissipative gelating materials that can switch between different acid/base states. The system is robust and resilient, with the chiral nature of amino acid gelator contributing to chiroptical switching properties.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Correction
Chemistry, Medicinal
David E. Uehling, Babu Joseph, Kim Chan Chung, Andrew X. Zhang, Spencer Ler, Michael A. Prakesch, Gennady Poda, Julie Grouleff, Ahmed Aman, Taira Kiyota, Chungyee Leung-Hagesteijn, John David Konda, Richard Marcellus, Carly Griffin, Ratheesh Subramaniam, Ayome Abibi, Craig A. Strathdee, Methvin B. Isaac, Rima Al-Awar, Rodger E. Tiedemann
JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Punit Saraon, Jamie Snider, Wiebke Schormann, Ankit Rai, Nikolina Radulovich, Maria Sanchez-Osuna, Jasmin Coulombe-Huntington, Caroline Huard, Mohammed Mohammed, Evelyne Lima-Fernandes, Brigitte Theriault, Levon Halabelian, Manuel Chan, Dhananjay Joshi, Luka Drecun, Zhong Yao, Shivanthy Pathmanathan, Victoria Wong, Anna Lyakisheva, Farzaneh Aboualizadeh, Li Niu, Fengling Li, Taira Kiyota, Ratheesh Subramanian, Babu Joseph, Ahmed Aman, Michael Prakesch, Methvin Isaac, Ahmed Mamai, Gennady Poda, Masoud Vedadi, Richard Marcellus, David Uehling, Natasha Leighl, Adrian Sacher, Miroslav Samarzija, Marko Jakopovic, Cheryl Arrowsmith, Mike Tyers, Ming-Sound Tsao, David Andrews, Rima Al-awar, Igor Stagljar
Summary: The small molecule EM166 was identified to inhibit mutant EGFR signalling and growth in NSCLC cells via a novel mechanism. EM166 affects the expression and signalling of certain proteins, alters subcellular localization, and modulates the ER stress response pathway in mutant EGFR lung cancer cells.
JOURNAL OF MOLECULAR BIOLOGY
(2021)
Article
Nanoscience & Nanotechnology
Enzo Olivieri, Baptiste Gasch, Guilhem Quintard, Jean-Valere Naubron, Adrien Quintard
Summary: This article reports the use of trichloroacetic acid (TCA) as fuel to create time-controlled materials that can reversibly switch between gel and solution states. These materials have interesting time-dependent properties and can be used in the generation of remoldable objects, erasing ink, chiroptical switches, and new types of electrical systems.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Guillaume Dauvergne, Jean-Valere Naubron, Michel Giorgi, Xavier Bugaut, Jean Rodriguez, Yannick Carissan, Yoann Coquerel
Summary: The synthetic equivalents of enantiopure binaphthyl bis(aryne) atropisomers derived from BINOL have been generated in a solution for the first time. These atropisomers can be prepared enantiospecifically in high enantiomeric purity using various reactions, leading to potential applications in nanographene design.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Morgane Mauduit, Stephane Greff, Gaetan Herbette, Jean-Valere Naubron, Sara Chentouf, Trung Huy Ngo, Joo-Won Nam, Sacha Molinari, Fathi Mabrouki, Elnur Garayev, Beatrice Baghdikian, Thierry Perez, Charlotte Simmler
Summary: Sponges are prolific producers of specialized metabolites with unique structural scaffolds, inspiring natural product chemists in drug discovery. This study aimed to determine the proportion and diversity of specialized metabolites released by the sponge Aplysina cavernicola, revealing the presence of brominated alkaloids in this sponge.
