Journal
ACS APPLIED MATERIALS & INTERFACES
Volume 2, Issue 4, Pages 1206-1210Publisher
AMER CHEMICAL SOC
DOI: 10.1021/am100045v
Keywords
nanoparticles; monolayers; cooperative adsorption; surface modification; silver; antibacterial
Funding
- Pew Scholarship in the Biomedical Sciences
- NIH [1R21CA137707-01]
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Cooperative electrostatic adsorption (CELA) is used to deposit monolayer coatings of silver nanoparticles on relatively chemically inert polymers, polypropylene, and Tygon. Medically relevant components (tubing, vials, syringes) coated by this method exhibit antibacterial properties over weeks to months with the coatings being stable under constant-flow conditions. Antibacterial properties of the coatings are due to a slow release of Ag+ from the particles. The rate of this release is quantified by the dithiol-precipitation method coupled with inductively coupled plasma optical emission spectrometer (ICP-OES) analysis.
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