Intestinal Microbiota in Animal Models of Inflammatory Diseases

Food, Immunity, and the Microbiome

(2015) Herbert Tilg et al.   GASTROENTEROLOGY

Diet in the Pathogenesis and Treatment of Inflammatory Bowel Diseases

(2015) Dale Lee et al.   GASTROENTEROLOGY

The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

(2014) Dirk Gevers et al.   Cell Host & Microbe

A Maternal Gluten-Free Diet Reduces Inflammation and Diabetes Incidence in the Offspring of NOD Mice

(2014) C. H. F. Hansen et al.   DIABETES

Fermentable fibres condition colon microbiota and promote diabetogenesis in NOD mice

(2014) Raine K. Toivonen et al.   DIABETOLOGIA

Abnormal fibre usage in UC in remission

(2014) Sally L James et al.   GUT

Inflammatory Bowel Disease as a Model for Translating the Microbiome

(2014) Curtis Huttenhower et al.   IMMUNITY

Induction of Bacterial Antigen-Specific Colitis by a Simplified Human Microbiota Consortium in Gnotobiotic Interleukin-10-/- Mice

(2014) C. S. Eun et al.   INFECTION AND IMMUNITY

Transmission of Atherosclerosis Susceptibility with Gut Microbial Transplantation

(2014) Jill C. Gregory et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

(2014) Yael Haberman et al.   JOURNAL OF CLINICAL INVESTIGATION

Potential of fecal microbiota for early-stage detection of colorectal cancer

(2014) G. Zeller et al.   Molecular Systems Biology

An enteric virus can replace the beneficial function of commensal bacteria

(2014) Elisabeth Kernbauer et al.   NATURE

Dominant Effects of the Diet on the Microbiome and the Local and Systemic Immune Response in Mice

(2014) Jot Hui Ooi et al.   PLoS One

The Gut Microbiota Modulates Glycaemic Control and Serum Metabolite Profiles in Non-Obese Diabetic Mice

(2014) Thomas U. Greiner et al.   PLoS One

Beneficial effects of human milk oligosaccharides on gut microbiota

(2014) S. Musilova et al.   Beneficial Microbes

Decreased Bacterial Diversity Characterizes the Altered Gut Microbiota in Patients With Psoriatic Arthritis, Resembling Dysbiosis in Inflammatory Bowel Disease

(2014) Jose U. Scher et al.   Arthritis & Rheumatology

Structure of the gut microbiome following colonization with human feces determines colonic tumor burden

(2014) Nielson T Baxter et al.   Microbiome

Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study

(2013) Mora Murri et al.   BMC Medicine

Gut Microbiota Protects against Gastrointestinal Tumorigenesis Caused by Epithelial Injury

(2013) Y. Zhan et al.   CANCER RESEARCH

Promotion of Autoimmune Diabetes by Cereal Diet in the Presence or Absence of Microbes Associated With Gut Immune Activation, Regulatory Imbalance, and Altered Cathelicidin Antimicrobial Peptide

(2013) C. Patrick et al.   DIABETES

Diet alters probioticLactobacilluspersistence and function in the intestine

(2013) Sybille Tachon et al.   ENVIRONMENTAL MICROBIOLOGY

Complex Interactions Among Diet, Gastrointestinal Transit, and Gut Microbiota in Humanized Mice

(2013) Purna C. Kashyap et al.   GASTROENTEROLOGY

A decrease of the butyrate-producing speciesRoseburia hominisandFaecalibacterium prausnitziidefines dysbiosis in patients with ulcerative colitis

(2013) Kathleen Machiels et al.   GUT

Gender Bias in Autoimmunity Is Influenced by Microbiota

(2013) Leonid Yurkovetskiy et al.   IMMUNITY

Inflammation-Induced Acid Tolerance GenesgadABin Luminal Commensal Escherichia coli Attenuate Experimental Colitis

(2013) Sandrine Tchaptchet et al.   INFECTION AND IMMUNITY

Semisynthetic Diet Ameliorates Crohn’s Disease–Like Ileitis in TNFΔARE/WT Mice Through Antigen-Independent Mechanisms of Gluten

(2013) Stefan J. Wagner et al.   INFLAMMATORY BOWEL DISEASES

Phylogenetic Analysis of Dysbiosis in Ulcerative Colitis During Remission

(2013) Mirjana Rajilić-Stojanović et al.   INFLAMMATORY BOWEL DISEASES

Gut Microbiota Affects Sensitivity to Acute DSS-induced Colitis Independently of Host Genotype

(2013) Brigitta M. Brinkman et al.   INFLAMMATORY BOWEL DISEASES

A metabolomic view of how the human gut microbiota impacts the host metabolome using humanized and gnotobiotic mice

(2013) A Marcobal et al.   ISME Journal

The Absence of a Microbiota Enhances TSLP Expression in Mice with Defective Skin Barrier but Does Not Affect the Severity of their Allergic Inflammation

(2013) Laura J. Yockey et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Gut metagenome in European women with normal, impaired and diabetic glucose control

(2013) Fredrik H. Karlsson et al.   NATURE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

The hypersensitivity to colonic distension of IBS patients can be transferred to rats through their fecal microbiota

(2013) L. Crouzet et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Intestinal Microbiota Composition of Interleukin-10 Deficient C57BL/6J Mice and Susceptibility to Helicobacter hepaticus-Induced Colitis

(2013) Ines Yang et al.   PLoS One

Commensal Bacteria-Dependent Indole Production Enhances Epithelial Barrier Function in the Colon

(2013) Yosuke Shimada et al.   PLoS One

Effects of Lactobacillus kefiranofaciens M1 Isolated from Kefir Grains on Germ-Free Mice

(2013) Yen-Po Chen et al.   PLoS One

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity

(2013) A. P. Liou et al.   Science Translational Medicine

Microbiota of De-Novo Pediatric IBD: Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative Colitis

(2012) Richard Hansen et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Genetic deletion of dectin-1 does not affect the course of murine experimental colitis

(2012) Sigrid EM Heinsbroek et al.   BMC GASTROENTEROLOGY

Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota

(2012) Hachung Chung et al.   CELL

Lactocepin Secreted By Lactobacillus Exerts Anti-Inflammatory Effects By Selectively Degrading Proinflammatory Chemokines

(2012) Marie-Anne von Schillde et al.   Cell Host & Microbe

Outer Membrane Vesicles of a Human Commensal Mediate Immune Regulation and Disease Protection

(2012) Yue Shen et al.   Cell Host & Microbe

The biodiversity and composition of the dominant fecal microbiota in patients with inflammatory bowel disease

(2012) Sumei Sha et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Gut microbiota composition correlates with diet and health in the elderly

(2012) Marcus J. Claesson et al.   NATURE

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

The Colitis-Associated Transcriptional Profile of Commensal Bacteroides thetaiotaomicron Enhances Adaptive Immune Responses to a Bacterial Antigen

(2012) Jonathan J. Hansen et al.   PLoS One

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease

(2011) Alan W Walker et al.   BMC MICROBIOLOGY

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Germ-free status and altered caecal subdominant microbiota are associated with a high susceptibility to cow's milk allergy in mice

(2011) Bertrand Rodriguez et al.   FEMS MICROBIOLOGY ECOLOGY

Chronic Intestinal Inflammation Induces Stress-Response Genes in Commensal Escherichia coli

(2011) Laura G. Patwa et al.   GASTROENTEROLOGY

Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation

(2011) Natalie Steck et al.   GASTROENTEROLOGY

Twin Study Indicates Loss of Interaction Between Microbiota and Mucosa of Patients With Ulcerative Colitis

(2011) Patricia Lepage et al.   GASTROENTEROLOGY

Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

(2011) Markus B. Geuking et al.   IMMUNITY

Lactobacillus reuteri promotes Helicobacter hepaticus-associated typhlocolitis in gnotobiotic B6.129P2-IL-10tm1Cgn (IL-10−/−) mice

(2011) Mark T. Whary et al.   IMMUNOLOGY

Absence of Microbiota (Germ-Free Conditions) Accelerates the Atherosclerosis in ApoE-Deficient Mice Fed Standard Low Cholesterol Diet

(2011) Renata Stepankova et al.   Journal of Atherosclerosis and Thrombosis

Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism

(2011) Fang Yan et al.   JOURNAL OF CLINICAL INVESTIGATION

Extreme genome reduction in symbiotic bacteria

(2011) John P. McCutcheon et al.   NATURE REVIEWS MICROBIOLOGY

The Incidence of Type-1 Diabetes in NOD Mice Is Modulated by Restricted Flora Not Germ-Free Conditions

(2011) Cecile King et al.   PLoS One

Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice

(2011) M. A. Kriegel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enterobacteriaceae Act in Concert with the Gut Microbiota to Induce Spontaneous and Maternally Transmitted Colitis

(2010) Wendy S. Garrett et al.   Cell Host & Microbe

A Pyrosequencing Study in Twins Shows That Gastrointestinal Microbial Profiles Vary With Inflammatory Bowel Disease Phenotypes

(2010) Ben P. Willing et al.   GASTROENTEROLOGY

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

(2010) Hsin-Jung Wu et al.   IMMUNITY

Commensal gut flora reduces susceptibility to experimentally induced colitis via T-cell-derived interleukin-101

(2010) Marina C. Pils et al.   INFLAMMATORY BOWEL DISEASES

Milk sialyllactose influences colitis in mice through selective intestinal bacterial colonization

(2010) Andrea Fuhrer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

(2010) Y. K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation

(2010) L. Dethlefsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Succession of microbial consortia in the developing infant gut microbiome

(2010) J. E. Koenig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal microflora functions in laboratory mice claimed to harbor a “normal” intestinal microflora. Is the SPF concept running out of date?

(2009) Elisabeth Norin et al.   ANAEROBE

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Diversification of the gut symbiont Lactobacillus reuteri as a result of host-driven evolution

(2009) Phaik Lyn Oh et al.   ISME Journal

Role of Gut Commensal Microflora in the Development of Experimental Autoimmune Encephalomyelitis

(2009) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

Charles River altered Schaedler flora (CRASF®) remained stable for four years in a mouse colony housed in individually ventilated cages

(2009) Matthias Stehr et al.   LABORATORY ANIMALS

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Allergic Sensitization to Bovine β-Lactoglobulin: Comparison between Germ-Free and Conventional BALB/c Mice

(2008) S. Hazebrouck et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA