Review
Medicine, General & Internal
Abhirup Chatterjee, Surinder Singh Rana
Summary: Embryological development of the pancreas can have multiple aberrations, but most ductal anomalies are asymptomatic. Accurate pre-operative diagnosis is important to prevent inadvertent duct injury during surgery. MRCP and EUS are effective tools for diagnosing ductal anomalies.
Article
Surgery
Christina J. Sperna Weiland, Evelien C. Verschoor, Alexander C. Poen, Xavier J. M. N. Smeets, Niels G. Venneman, Abha Bhalla, Ben J. M. Witteman, Hester C. Timmerhuis, Devica S. Umans, Jeanin E. van Hooft, Marco J. Bruno, P. Fockens, Robert C. Verdonk, Joost P. H. Drenth, Erwin J. M. van Geenen
Summary: Even with advanced imaging techniques, the presence of common bile duct sludge or stones can be missed during ERCP. Pre-procedural EUS or MRCP can reduce the proportion of unnecessary ERCPs. A shorter time interval between EUS or MRCP and ERCP increases the detection rate of suspected CBD stones during ERCP.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Gastroenterology & Hepatology
Masato Suzuki, Yusuke Sekino, Kunihiro Hosono, Kouji Yamamoto, Kenichi Kawana, Hajime Nagase, Kensuke Kubota, Atsushi Nakajima
Summary: This study compared the diagnostic accuracy of endoscopic ultrasound (EUS) and magnetic resonance cholangiopancreatography (MRCP) for suspected common bile duct stones (CBDS) missed on computed tomography (CT). The results showed that EUS had higher accuracy and detection rate for CBDS in the second examination.
DIGESTIVE ENDOSCOPY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhiyong Chen, Bin Sun, Yunjing Xue, Qing Duan, Enshuang Zheng, Yingying He, Guijin Li, Zhongshuai Zhang
Summary: This study compared the image quality and consistency of different MRCP methods in patients with suspected pancreaticobiliary diseases. The results showed that 3D-BH-CS-MRCP had significantly higher contrast ratio, SNR, and CNR for the CBD, while 3D-BH-PI-MRCP provided better visualization of the segment 2 and 3 branch of the intrahepatic duct.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Review
Gastroenterology & Hepatology
Keiji Hanada, Akihiro Shimizu, Keisuke Kurihara, Morito Ikeda, Takuya Yamamoto, Yasuhiro Okuda, Susumu Tazuma
Summary: Early diagnosis of pancreatic ductal adenocarcinoma (PDAC) is crucial for improving prognosis, but it is challenging to diagnose PDAC at an early stage. Pancreatic cystic lesions or main pancreatic duct (MPD) dilatation are important indirect findings for the initial diagnosis of HG-PanIN. Magnetic resonance cholangiopancreatography (MRCP) and endoscopic ultrasound (EUS) play significant roles in detecting abnormal image findings.
DIGESTIVE ENDOSCOPY
(2022)
Review
Gastroenterology & Hepatology
Jin Hui Yi, Zhao Shen Li, Liang Hao Hu
Summary: Pancreatic duct stenting is a widely used method for managing pancreatic diseases. Endoscopic stents are used to relieve pain, treat disruptions and narrowings, prevent complications, treat cancer, and locate stones. Recent advances in techniques and stent designs have expanded the indications for pancreatic duct stenting. This review outlines the types, procedures, efficacy, and complications of endoscopic stent placement, and summarizes their applications in surgery.
JOURNAL OF DIGESTIVE DISEASES
(2023)
Review
Gastroenterology & Hepatology
Masaki Kuwatani, Naoya Sakamoto
Summary: The dismal prognosis of pancreaticobiliary malignancies is mainly due to the difficulty in detecting early-stage lesions. Recent studies have focused on using liquid biopsy and proteomics/metabolomics analysis, in combination with artificial intelligence, for early cancer detection. Additionally, pathological analysis and innovative sampling methods have been developed to support early-stage cancer diagnosis.
DIGESTIVE ENDOSCOPY
(2022)
Review
Medicine, General & Internal
Yasutaka Ishii, Masahiro Serikawa, Tomofumi Tsuboi, Ryota Kawamura, Ken Tsushima, Shinya Nakamura, Tetsuro Hirano, Ayami Fukiage, Takeshi Mori, Juri Ikemoto, Yusuke Kiyoshita, Sho Saeki, Yosuke Tamura, Sayaka Miyamoto, Kazuaki Chayama
Summary: Endoscopic ultrasonography (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) play important roles in the diagnosis of pancreatic cancer. EUS has higher sensitivity for detecting small pancreatic cancer, while ERCP is essential for evaluating pancreatic duct stricture.
Review
Gastroenterology & Hepatology
Pradeep K. Siddappa, Fadi Hawa, Larry J. Prokop, M. Hassan Murad, Barham K. Abu Dayyeh, Vinay Chandrasekhara, Mark D. Topazian, Fateh Bazerbachi
Summary: Endoscopic pancreatic duct decompression may be an effective and safe option for managing obstructive-type pancreatic cancer pain in selected patients, with potential for partial or complete improvement in pain levels. However, further randomized controlled trials are needed to determine the specific role of this invasive practice.
GASTROENTEROLOGY REPORT
(2021)
Article
Gastroenterology & Hepatology
Jia Yu Zhang, Zhao Hui Deng, Biao Gong
Summary: In this study, we retrospectively analyzed the clinical characteristics of 148 pediatric patients with pancreatitis and pancreaticobiliary malformation. We found that pancreaticobiliary malformation was associated with the development of pancreatitis. Patients with pancreaticobiliary maljunction were younger and more likely to have jaundice and fever compared to those with pancreatic divisum. Genetic mutations were found in a significant proportion of patients with pancreatic divisum and annular pancreas. MRCP had limited diagnostic value for identifying pancreaticobiliary malformation in children. ERCP was effective and safe for the diagnosis and treatment of pediatric pancreatitis caused by pancreaticobiliary malformation.
JOURNAL OF DIGESTIVE DISEASES
(2022)
Article
Surgery
Chan Hyuk Park, Moon Jae Chung, Da Hae Park, Seonjeong Min, Se Woo Park
Summary: Fatty pancreas is a significant risk factor for the development of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP). Clinicians need to be aware of the risk of fatty pancreas for the development of PEP prior to performing ERCP.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Hirokazu Saito, Hajime Iwasaki, Hisashi Itoshima, Yoshihiro Kadono, Takashi Shono, Kentaro Kamikawa, Atsushi Urata, Jiro Nasu, Masayoshi Uehara, Ikuo Matsushita, Tatsuyuki Kakuma, Shuji Tada
Summary: High-risk patients with suspected common bile duct stones (CBDSs) based on the revised ASGE guideline 2019 have a high detection rate of CBDS during endoscopic retrograde cholangiopancreatography (ERCP). However, performing ERCP on patients with only clinical predictors often results in unnecessary procedures.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Gastroenterology & Hepatology
Jacob A. Mark, Robert E. Kramer
Summary: For pediatric patients undergoing ERCP with manipulation of the pancreatic duct, ketorolac was associated with a lower rate of PEP. Ketorolac was well tolerated without an increased risk of bleeding after ERCP. This study provides evidence of an association between intraoperative NSAID use and lower rates of PEP in specific pediatric patients.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2021)
Article
Medicine, General & Internal
Yajie Meng, Jiewen Ding, Chuan Tian, Min Wang, Kejiang Tang
Summary: For patients with WOPN and complete MPD disruption, endoscopic PTD with FCSEMSs and plastic stent placement may be an effective and safe treatment method.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Seong Chan Gong, Sanghyun An, In Sik Shin, Pil Young Jung
Summary: Pediatric trauma patients are on the rise, with trauma being the leading cause of death in children. Pancreatic injury is the fourth most common solid organ injury and often suffers from delayed diagnosis due to its retroperitoneal location and the limited accuracy of diagnostic tests. While endoscopic retrograde cholangiopancreatography (ERCP) is a valuable tool for diagnosing and treating various biliary and pancreatic diseases, its application in traumatic pancreatic injury cases in children has been rarely reported. This study aimed to assess the effectiveness of ERCP in diagnosing and managing traumatic pancreatic injury in children. The results showed that ERCP could be beneficial in diagnosing and treating such injuries without increasing complications.