Use of Preclinical Dog Studies and Absorption Modeling to Facilitate Late Stage Formulation Bridging for a BCS II Drug Candidate

Case Studies for Practical Food Effect Assessments across BCS/BDDCS Class Compounds using In Silico, In Vitro, and Preclinical In Vivo Data

(2012) Tycho Heimbach et al.   AAPS Journal

Effective Absorption Modeling in Relative Bioavailability Study Risk Assessment

(2012) John P. Rose   AAPS Journal

Utility of Physiologically Based Absorption Modeling in Implementing Quality by Design in Drug Development

(2011) Xinyuan Zhang et al.   AAPS Journal

Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans

(2010) Yasushi Shono et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The Developability Classification System: Application of Biopharmaceutics Concepts to Formulation Development

(2010) James M. Butler et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Predicting Pharmacokinetics of Drugs Using Physiologically Based Modeling—Application to Food Effects

(2009) N. Parrott et al.   AAPS Journal

Prediction of Modified Release Pharmacokinetics and Pharmacodynamics from In Vitro, Immediate Release, and Intravenous Data

(2009) Viera Lukacova et al.   AAPS Journal

Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

(2009) Kiyohiko Sugano   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Understanding the Effect of API Properties on Bioavailability Through Absorption Modeling

(2008) Filippos Kesisoglou et al.   AAPS Journal